Results 41 to 50 of about 2,940 (175)

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

Oxidations of Benzhydrazide and Phenylacetic Hydrazide by Hexachloroiridate(IV): Reaction Mechanism and Structure–Reactivity Relationship

Molecules, 2020
Benz(o)hydrazide (BH) is the basic aryl hydrazide; aryl hydrazides have been pursued in the course of drug discovery. Oxidations of BH and phenylacetic hydrazide (PAH) by hexachloroiridate(IV) ([IrCl6]2−) were investigated by use of stopped-flow ...
Xiaolai Zhang
doaj   +1 more source

Defect Suppression via Tailoring Functionalized Additives for Efficient and Stable CsPbI3 Perovskite Solar Cells

Carbon Energy, EarlyView.
This study proposed a structure‐designed benzohydrazide derivative, namely 4‐methoxybenzohydrazide (MeOBH), as an additive to regulate crystallization, passivate defects, optimize energy‐level structure, and enhance phase stability of β‐CsPbI3 perovskite films.
Haiyan Zhao, Chunyan Li, Yao Zhang, Zhongxun Yu, Jixiang Zhang, Xiaoan Tang, Zi Ouyang, Haipeng Yin, Yang Sun, Hao Du, Han Chen   +10 more
wiley   +1 more source

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

Chemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda, Alan Pham, SreeNidhi Karnati, Natalia Soto Rodriguez, Alyssa Toner, Wenshe Ray Liu   +5 more
wiley   +1 more source

Synthesis and In Vitro Anticancer Activity of Pyrrolidone Derivatives Bearing 3,4,5-Trimethoxyphenyl Moiety as a Promising Anticancer Scaffold

Applied Sciences
A series of 5-oxo-1-(3,4,5-trimethoxyphenyl)pyrrolidine-3-carboxylic acid derivatives–hydrazones, N-ethylhydrazones, pyrrole, pyrazole, oxadiazole, and triazole were synthesized and evaluated for their anticancer activity using human A549 pulmonary ...
Povilas Kavaliauskas, Birutė Sapijanskaitė-Banevič, Birutė Grybaitė, Eglė Mickevičiūtė, Kazimieras Anusevičius, Andrew Garcia, Ethan Naing, Rūta Petraitienė, Vidmantas Petraitis, Ramunė Grigalevičiūtė, Vytautas Mickevičius   +10 more
doaj   +1 more source

A new class of dihaloquinolones bearing N'-aldehydoglycosylhydrazides, mercapto-1,2,4-triazole, oxadiazoline and a-amino ester precursors: synthesis and antimicrobial activity

Journal of the Brazilian Chemical Society, 2003
Reaction of the quinolones 6-8 with hydrazine afforded the hydrazide 9-11 in moderate yields. Condensation of 9 and 11 with CS2 /KOH furnished the potassium salts 13 and 14, respectively, which spontaneously afforded the 3-(1,2,4-triazolyl)-quinolones 15
Al-Soud Yaseen A., Al-Masoudi Najim A.
doaj  

Pemodelan Molekul Turunan p-Metoksi sinnamoil Hidrazida Sebagai Inhibitor Checkpoint Kinase 1 dan Inhibitor Aromatase secara In silico

Pharmaceutical Sciences and Research, 2017
The development of anticancer drugs from ethyl p-methoxycinnamate (EPMC) derivatives continues to obtain compounds that have high ability of cancer cells apoptosis and minimal side effects.
Galih Satrio Putra, Melanny Ika Sulistyowaty, Juni Ekowati   +2 more
doaj   +1 more source

Identification of Natural Isonitriles Through Ligation to an Azomethine Imine Probe

Chemistry – A European Journal, EarlyView.
The azomethine imine (AMI)–isonitrile (NC) ligation allowed for the chemoselective detection of natural isonitriles in bacteria and fungi. The reactivity‐based screening establishes a new stereogenic center, thereby allowing for facile distinction between chiral and achiral isonitriles. The work also unraveled a unique reactivity of isonitriles bearing
Maurice P. Biedermann, Alexander Brachmann, Shurui Mai, Athanasios Markos, Markus Künzler, Jörn Piel, Helma Wennemers   +6 more
wiley   +1 more source

Ultra‐High Strength and Environmentally Stable Fluorinated Solid‐State Ion‐Conductive Elastomers with Folding‐Paper‐Structured Triboelectric Nanogenerators for Wave Energy Harvesting

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
In this work, a polyurethane‐based fluorinated SICEs with excellent mechanical properties (7.35 MPa and 61.4 MJ m−3), conductivity (4.2 × 10−4 S cm−1), and harsh environmental resistance were prepared by a “three birds with one stone” strategy that combines multiple interactions with fluorine effects. The paper‐folding TENG is capable of harvesting not
Zequan Li, Fangyan Ou, Wei Tang, Fuqi Wang, Zhichao Zhang, Ting Xie, Chuang Ning, Wenyu Pan, Wei Gao, Shuangliang Zhao   +9 more
wiley   +1 more source

Hypervalent Iodine‐Mediated Synthesis of Sulfones Using Organozinc Pivalates and Sulfinate Salts

European Journal of Organic Chemistry, EarlyView.
A general protocol for sulfone synthesis via sulfonyl‐containing hypervalent iodine reagents and organozinc pivalates is described. The method is practical, provides a broad scope of sulfone in moderate to high yield. bicyclo[1.1.1]pentane‐sulfones are also disclosed and a one‐pot synthesis of Diels–Alder adduct is presented. Sulfones are key motifs in
José C. Cunha, Gabriel G. Rocha, Fábio M. F. Santos, Stefan Bräse, M. Manuel B. Marques   +4 more
wiley   +1 more source