Results 71 to 80 of about 5,842 (193)
ChemistryOpen, 2020 The optimization and modulation of the properties of photochromic compounds, such as their activation wavelengths and thermal relaxation half‐lives (τ1/2), are essential for their adaptation in various applications. In this work, we studied the effect of
Baihao Shao, Prof. Dr. Ivan Aprahamian
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Stimuli‐responsive hydrogels: An intelligent tool for wound management
Interdisciplinary Medicine, EarlyView.For chronic and complex wounds, this review focuses on intelligent hydrogels capable of responding to wound microenvironmental cues (e.g., pH, enzymes) or external stimuli (e.g., light, electricity). These advanced materials enable the dynamic regulation of drug release and real‐time monitoring of healing progression, thereby offering innovative ...
Debin Zheng +10 more
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C–H Trifluoromethylthiolation of aldehyde hydrazones
Beilstein Journal of Organic ChemistryThe selective C–H trifluoromethylthiolation of aldehyde hydrazones afforded interesting fluorinated building blocks, which could be used as a synthetic platform.
Victor Levet +3 more
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Recent progress on stimuli‐responsive chitosan‐based biomaterials as drug carriers
Interdisciplinary Medicine, EarlyView.This review discusses the recent progress in chitosan‐based drug delivery systems that respond to pH, redox, enzymes, reactive oxygen species, and combined stimuli. It examines design strategies, key mechanisms, and therapeutic applications, and also addresses current challenges while suggesting future approaches to enhance clinical translation and ...
Changlu Xu +4 more
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Journal of Applied Toxicology, EarlyView.ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu +6 more
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Studia Universitatis Moldaviae: Stiinte reale si ale naturii, 2012 Nine hydrazones have been obtained on the basis of 2-hydrazinobenzothiazole. The obtained hydrazones inhibits the growth of HL-60 cells of human leukemia myeloid within the concentrations of 10-5-10-6 mol/l.
USM ADMIN
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Macromolecular Rapid Communications, EarlyView.We report here a new methodology to prepare functional poly(acetylene)s under aqueous conditions. This methodology is underpinned by poly(O‐propargyl‐N‐amino carbamate) (P1), a reactive poly(acetylene) carrying acyl hydrazines. Thus, P1 reacts with aldehydes to give functional poly(acetylene)s, including cationic, hydrophobic, and sugar‐loaded poly ...
Tom Leigh +8 more
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One-Pot Synthesis of Novel Thiazoles as Potential Anti-Cancer Agents
Drug Design, Development and Therapy, 2020 Abdelwahed R Sayed,1,2 Sobhi M Gomha,3,4 Eman A Taher,5,6 Zeinab A Muhammad,5 Hesham R El-Seedi,6,7 Hatem M Gaber,5 Mahgoub M Ahmed8 1Department of Chemistry, Faculty of Science, KFU, Hofuf, Saudi Arabia; 2Department of Chemistry, Faculty of Science ...
Sayed AR +6 more
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The synthesis and characterization of some novel 5-chloro-2-(substituted alkoxy)-N-phenylbenzamide derivatives [PDF]
Journal of the Serbian Chemical Society, 2009 To obtain biologically active compounds, the synthesis of some new derivatives with an o-hydroxybenzamide structure was performed. The ethyl esters 4–6 were obtained by the reaction of 5-chloro-2-hydroxy-N-phenylbenzamide and chloro-substituted acid ...
IOANA M. C. IENAŞCU +4 more
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Macromolecular Rapid Communications, EarlyView.Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
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