Results 81 to 90 of about 50,011 (341)
Advanced Science, EarlyView.Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang +10 more
wiley +1 more source
Reaction of Nitrilimines and Nitrile Oxides with Hydrazines, Hydrazones and Oximes
Molecules, 2005 This review article discusses the reaction of nitrilimines and nitrile oxides with hydrazines, hydrazones, and oximes. Three reaction modes were observed.
Adel M. Awadallah +1 more
doaj +1 more source
Advanced Science, EarlyView.A universal ROR1 antibody‐engineered lipid nanoparticle (LNP) is constructed by sequential drug encapsulation and antibody conjugation. The LNP not only enables enhanced chemotherapeutic efficiency by targeting drug delivery and precise localization of deep‐seated tumors through NIR‐II fluorescence imaging, but also remodels immunosuppressive TME ...
Yeneng Dai +12 more
wiley +1 more source
MoleculesOur group has seen great promise in using substituted diaryl-hydrazones to alleviate oxidative stress in preeclampsia. Specifically, fluorinated diaryl-hydrazones have shown great efficacy, confirmed via antioxidant assays and animal trials using ...
Maximilian Costa +7 more
doaj +1 more source
Advanced Science, EarlyView.Random ssDNA–SWCNT(single strand DNA‐single walled carbon nanotube) library is functionally screened and evolved using high‐throughput 3D prostate tumor spheroids via iterative positive and negative selection, enabling the identification of NIR‐II fluorescent ssDNA‐SWCNT nanoprobe specific for prostate cancer.
Dakyeon Lee +8 more
wiley +1 more source
Preparation of organic hydrazides [PDF]
, 1959 Thesis (M.A.)--Boston UniversityDue to the actual high price of hydrazine, this chemical cannot be used in an economical preparation of organic hydrazides. A synthesis of such hydrazides can be envisaged by the reduction of N-nitroamides.
Amiel, Jean-Pierre L.
core +1 more source
Ugi post-condensation copper-triggered oxidative cascade towards pyrazoles
, 2011 International audiencePyrazolidinones were prepared in a two-step sequence starting from a-hydrazonocarboxylic acids. After a four-component Ugi coupling, the resulting hydrazone was engaged in a copper triggered [3 + 2] cycloaddition/aerobic oxidation ...
dos Santos, Aurélie +3 more
core +5 more sources
2,20-Dihydroxybenzophenones and their carbonyl N-analogues as inhibitor scaffolds for MDR-involved human glutathione transferase isoenzyme A1-1 [PDF]
, 2014 The MDR-involved human GSTA1-1, an important isoenzyme overexpressed in several tumors leading to chemotherapeutic-resistant tumour cells, has been targeted by 2,2′-dihydroxybenzophenones and some of their carbonyl N-analogues, as its potential ...
Clonis, Yannis D. +7 more
core +1 more source
Advanced Science, EarlyView.This study pioneers an aggregation‐induced resonance energy transfer mechanism by synergistically integrating aggregation‐induced emission (AIE), resonance energy transfer (RET), and thermally activated delayed fluorescence (TADF) within co‐reactant conjugated polymers to develop self‐enhanced ECL emitters, which achieves an ECL efficiency up to 92.6 ...
Chao Wang +6 more
wiley +1 more source
ChemistryOpen, 2020 A coumarin based probe for the efficient detection of hydrogen sulfide in aqueous medium is reported. The investigated coumarine‐based derivative forms spherical nanoparticles in aqueous media.
Dr. Joydev Hatai +3 more
doaj +1 more source