New Route Synthesis of Thiadiazoles, Bisthiadiazoles, Thiadiazolotriazines, and Pyrazolothiadiazoles Based on Hydrazonoyl Halides and Dihydrazinylthiadiazole. [PDF]
Molecules, 2017 Synthesis and characterization of new thiadiazoles, bisthiadiazoles from the reaction of mono- and di-hydrazonoyl halides with various hydrazinecarbodithioate derivatives were studied. Treatment of hydrazonoyl halides with 2,5-dihydrazinyl-1,3,4-thiadiazole afforded new bistriazines containing thiadiazole; we also examined the reaction of 2,5 ...
Sayed AR, Al-Shihry SS.
europepmc +9 more sources
Synthesis and characterization of novel heterocycles based on tetrazine and hydrazonoyl halides [PDF]
European Journal of Chemistry, 2014 The present work describes the preparation and characterization of new pyridazine, thiohydrazonate, bis -pyrazole, bis -triazole and polypyrazoles based on tetrazine and hydrazonoyl halides. The structures of the newly synthesized were elucidated on the basis of their spectral data FT-IR, NMR, Mass and elemental analysis.
Abdelwahed R. Sayed +2 more
core +7 more sources
Angular Regioselective Synthesis of Varied Functionalized Hexahydro-1,2,4-triazolo[4,3-a]quinazolin-9-ones and Their Antiproliferative Action. [PDF]
Molecules, 2023 New 2-thioxopyrimidin-4-ones capable of participating in regioselective reactions with functionally diverse hydrazonoyl chlorides towards angular regioisomers, rather than linear ones, were designed and synthesized to form stereoisomeric cis- and trans ...
Said AI +4 more
europepmc +3 more sources
Reactions with Hydrazonoyl Halides. Part 21. Reinvestigation of the Reactions of Hydrazonoyl Bromides with 1,1-Dicyanothioacetanilide [PDF]
Journal of Chemical Research, 1999 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Hussein F. Zohdi +2 more
+6 more sources
Reaction of Nitrilimines with Pyruvaldehyde Hydrazones: Synthesis and Antimicrobial Evaluation of Some New 1,2,4‐Triazole Derivatives [PDF]
Journal of Chemistry, Volume 2015, Issue 1, 2015., 2015 A new series of 1,3,4,5,5‐pentasubstituted‐1,2,4‐triazoles (4a–j, 6a–j) have been synthesized by the 1,3‐dipolar cycloaddition of suitable nitrilimines 2 to pyruvaldehyde (2‐oxopropanal) hydrazones having (COPh, COOMe, COOEt, Me/Me, and Me/Ph) groups 3 and 5.
Hany M. Dalloul, Sevgi Kolaylı
wiley +3 more sources
Electrochemical Synthesis of Pyrazolines and Pyrazoles via [3+2] Dipolar Cycloaddition [PDF]
Angewandte Chemie International Edition, Volume 62, Issue 9, February 20, 2023., 2023 Electrochemically initiated [3 2] cycloaddition reactions of readily available and less toxic starting materials enable a facile synthesis of pyrazolines and pyrazoles. Application of a biphasic system and sodium iodide in a dual role as mediator and electrolyte allows for selective reactions with outstanding robustness towards scalability.
Martin Linden +5 more
wiley +3 more sources
Synthesis, Molecular Docking, and Dynamic Simulation Targeting Main Protease (Mpro) of New, Thiazole Clubbed Pyridine Scaffolds as Potential COVID-19 Inhibitors. [PDF]
Curr Issues Mol Biol, 2023 Many biological activities of pyridine and thiazole derivatives have been reported, including antiviral activity and, more recently, as COVID-19 inhibitors.
Alghamdi A +7 more
europepmc +3 more sources
European Journal of Organic Chemistry, Volume 26, Issue 47, December 13, 2023., 2023 1,3‐dipolar cycloaddition of cyclic enones with 2,5‐disubstituted nitrile‐imines obtained by photochemical activation of 2,5‐diaryl substituted tetrazoles leads to the formation of novel pyrazoles and pyrazolines. Reactions can be monitored using UV‐vis absorption and emission measurements.
Chiraz Labassi +4 more
wiley +1 more source
Synthetic Routes to Imidates and Their Applications in Organic Transformation: Recent Progress
European Journal of Organic Chemistry, Volume 26, Issue 39, October 16, 2023., 2023 Imidates are important organic intermediates used in several synthetic transformations towards N‐heterocycles, natural products and metal complexes with a potential catalytic effect. Herein, the recent synthetic approaches and diverse applications of imidates were categorized and summarized.
Andriani G. Chaidali, Ioannis N. Lykakis
wiley +1 more source
Different Synthetic Methods for the Preparation of Triazolopyrimidines and their Biological Profile
ChemistrySelect, Volume 8, Issue 23, June 20, 2023., 2023 This review aims to give a broad overview of the synthetic methods, starting from aminotriazoles and pyrimidines, leading to heterocyclic systems containing the triazolopyrimidine ring and presenting the reactivity of these derivatives. Additionally, we have summarized the most important biological activities.
Achraf Hibot +4 more
wiley +1 more source