A review on bis-hydrazonoyl halides: Recent advances in their synthesis and their diverse synthetic applications leading to bis-heterocycles of biological interest. [PDF]
This review covers a summary of the literature data published on the chemistry of bis-hydrazonoyl halides over the last four decades. The biological activities of some of the bis-heterocyclic compounds obtained from these bis-hydrazonoyl halides are also
Shawali AS.
europepmc +3 more sources
Reactions with Hydrazonoyl Halides. 31. Synthesis of Some New Pyrrolidino[3,4-c]pyrazolines, Pyrazoles, and Pyrazolo[3,4-d]pyridazines [PDF]
Pyrrolidino[3,4-c]pyrazoline and pyrazole derivatives were synthesized via reactions of a substituted hydrazonoyl bromide with N-arylmaleimides and active methylene reagents, respectively. Synthesized pyrazoles were reacted with hydrazine hydrate to give
Nagla A. Ahmed+3 more
doaj +2 more sources
Reactions with hydrazonoyl halides 65: Synthesis of some new 1,3,4-thiadiazoles and triazolino[4,3-a]pyrimidines containing pyrazole moiety [PDF]
2,3-Dihydro-1,3,4-thiadiazoles, and triazolino[4,3-a]pyrimidines containing pyrazole moieties were prepared from the reaction of alkyl 2-[1-(4-cyano-1,5-diphenyl-1H-pyrazol-3-yl)ethylidene]hydrazinecarbodithioate and pyrimidine-2-thione derivatives with ...
Abdelhamid, Abdou Osman+2 more
core +3 more sources
Hydrazonoyl Halides: Their Versatile Biological Activities [PDF]
The various biological activities namely anthelmintic, antiarthropodal, antiviral, antimicrobial, herbicidal, antisarcoptic, acaricidal, insecticidal and miticidal activities exhibited by the hydrazonoyl halides are surveyed. Also, the uses of such halides as pesticides, weed controlling and antihypertensive agents as well as lipoxygenase and cyclo ...
Nevien Samy, Ahmad S. Shawali
openaire +3 more sources
Reactions with hydrazonoyl halides 66: Synthesis of some new 1,3,4-thiadiazoles, triazolino[4,3-a]pyrimidines and isoxazolo[3,4-d]pyridazines containing coumarin moiety [PDF]
2,3-Dihydro-1,3,4-thiadiazoles, triazolino[4,3-a]pyrimidines, isoxazoles and isoxazolo[3,4-d]pyridazines containing coumarin moities were synthesized from the reactions of methyl (or benzyl) carbodithioate, pyrimidine-2-thione and 3-(3-(dimethylamino ...
Abdelhamid, Abdou Osman+2 more
core +3 more sources
Hydrazonoyl Halides as Precursors for Synthesis of Novel Bioactive Thiazole and Formazan Derivatives [PDF]
A new series of substituted 4-methyl-5-(arylazo)-2-[ N‘-(6,7,8,9-tetrahydro-benzocyclohepten-5-ylidene)-hydrazino]-thiazoles and 5-(arylhydrazono)-2-[ N‘-(6,7,8,9-tetrahydro-benzocyclohepten-5-ylidene)-hydrazino]-thiazol-4-one were prepared by reaction of hydrazonoyl chlorides with a thiosemicarbazone derivative.
Eman M. H. Abbas, Thoraya A. Farghaly
openaire +3 more sources
Design, Synthesis, and Biological Evaluations of Novel Azothiazoles Based on Thioamide. [PDF]
Herein we studied the preparation of different thiazoles via the reaction of 2-(3,4-dimethoxybenzylidene)hydrazine-1-carbothioamide (1) with hydrazonoyl halides under base-catalyzed conditions.
Sayed AR+4 more
europepmc +2 more sources
Synthesis and In Silico Study of Some New bis-[1,3,4]thiadiazolimines and bis-Thiazolimines as Potential Inhibitors for SARS-CoV-2 Main Protease. [PDF]
A novel series of bis-[1,3,4]thiadiazolimines, and bis-thiazolimines, with alkyl linker, were synthesized through general routes from cyclization of 1,1′-(hexane-1,6-diyl)bis(3-phenylthiourea) and hydrazonoyl halides or α-haloketones, respectively ...
Gomha SM+7 more
europepmc +2 more sources
Synthesis and Molecular Docking of Some Novel 3-Thiazolyl-Coumarins as Inhibitors of VEGFR-2 Kinase. [PDF]
One crucial strategy for the treatment of breast cancer involves focusing on the Vascular Endothelial Growth Factor Receptor (VEGFR-2) signaling system. Consequently, the development of new (VEGFR-2) inhibitors is of the utmost importance. In this study,
Abolibda TZ+4 more
europepmc +2 more sources
Reactions with hydrazonoyl halides XXVIII*: Synthesis of some 2-thiazolylimino-2,3-dihydro-1,3,4-thiadiazoles [PDF]
Nabil M. Hassan+2 more
+5 more sources