Results 41 to 50 of about 5,125,991 (297)

Blood, urine and cerebrospinal fluid analysis in TH and AADC deficiency and the effect of treatment

Molecular Genetics and Metabolism Reports, 2021
Background: Aromatic L-amino acid decarboxylase (AADC) deficiency and tyrosine hydroxylase (TH) deficiency are rare inherited disorders of monoamine neurotransmitter synthesis which are typically diagnosed using cerebrospinal fluid examination of ...
Tessa Wassenberg, Ben P.H. Geurtz, Leo Monnens, Ron A. Wevers, Michèl A. Willemsen, Marcel M. Verbeek   +5 more
doaj   +1 more source

Predicting Suicidal Behavior: Are We Really that Far Along? Comment on “Discovery and Validation of Blood Biomarkers for Suicidality” [PDF]

, 2013
A recent publication focused on biomarkers of future suicidal behaviors identifies several genes expressed in high-risk states among four samples. We discuss the implications of this study as well as the current state of research regarding biomarkers of ...
Baca-García, Enrique, Blasco-Fontecilla, Hilario, Giner Jiménez, Lucas, Lopez Castroman, Jorge, Oquendo, María   +4 more
core   +1 more source

Alterations in Monoamine Metabolites in Alzheimer's Disease: A Comprehensive Meta‐Analysis of Cerebrospinal Fluid Levels [PDF]

Alzheimers Dement
Abstract Background Alzheimer's disease (AD) is a neurodegenerative disorder marked by cognitive decline and neuropsychiatric symptoms. The monoaminergic system, crucial for mood, cognition, and behavior regulation, is implicated in AD pathology. Alterations in monoamine metabolites like 3,4‐dihydroxyphenylacetic acid (DOPAC), 5‐hydroxyindoleacetic ...
Muneer M, Agarwa H, Gowda P, Azmi M, Yadav P, Ghosh V, Hassan M, Kaur A, Suresh V, Azzam A, Bardhan M.   +10 more
europepmc   +4 more sources

Novel multimetabolite prediction of walnut consumption by a urinary biomarker model in a free-living population: the PREDIMED Study [PDF]

, 2017
The beneficial impact of walnuts on human health has been attributed to their unique chemical composition. In order to characterize the dietary walnut fingerprinting, spot urine samples from two sets of 195 (training) and 186 (validation) individuals ...
Andrés Lacueva, Ma. Cristina, Corella Piquer, Dolores, Estruch Riba, Ramon, Fitó Colomer, Montserrat, Garcia Aloy, Mar, Llorach, Rafael, Martínez-González, Miguel Ángel, 1957-, Ros Rahola, Emilio, Salas Salvadó, Jordi, Tulipani, Sara, Urpí Sardà, Mireia   +10 more
core   +1 more source

Thirty-Second Net Stressor Task in Adult Zebrafish

Bio-Protocol, 2015
Zebrafish have become a popular animal model for behavioral neuroscience (Gerlai, 2014). Recent studies have demonstrated that brief experimental handling prior to euthanizing animals can subsequently alter biological measures quantified post-mortem (e.g.
Steven Tran, Robert Gerlai
doaj   +1 more source

Tryptophan in banana peel (Musa paradisiaca) as an anti-dementia alternative treatment: A narrative review

JKKI (Jurnal Kedokteran dan Kesehatan Indonesia), 2021
As the prevalence of dementia increases from year to year, the discovery and invention of preventive measures are growing increasingly urgent. Banana peels contain tryptophan, an amino acid that plays a substantial role in the mechanism of dementia ...
Daffara Kinanthi Lustikaiswi, Sapto Yuliani, Rahmah Annura, Elmi Rahmadani   +3 more
doaj   +1 more source

Progression of Carcinoid Heart Disease in the Modern Management Era

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background The development of carcinoid heart disease (CaHD) is still relatively unclear. It is difficult to define an optimal follow‐up for patients without any cardiac involvement at baseline.
Emilie Baron, Catherine Szymanski, Hélène Hergault, Céline Lepère, Olivier Dubourg, Marie Hauguel‐Moreau, Nicolas Mansencal   +6 more
doaj   +1 more source

Biochemical and Genetic Studies of UBR3, a Ubiquitin Ligase with a Function in Olfactory and Other Sensory Systems [PDF]

, 2007
Our previous work identified E3 ubiquitin ligases, termed UBR1-UBR7, that contain the ~70-residue UBR box, a motif important for the targeting of N-end rule substrates.
Hellweg, Rainer, Hörtnagl, Heidi, Kwon, Yong Tae, Sohr, Reinhard, Tasaki, Takafumi, Varshavsky, Alexander, Xia, Zanxian   +6 more
core   +1 more source

Acute Inflammatory Bowel Disease Complicating Chronic Alcoholism and Mimicking Carcinoid Syndrome

Case Reports in Gastroenterology, 2012
We report the case of a woman with a history of chronic alcohol abuse who was hospitalized with diarrhea, severe hypokalemia refractory to potassium infusion, nausea, vomiting, abdominal pain, alternations of high blood pressure with phases of ...
Piercarlo Ballo, Pietro Dattolo, Giuseppe Mangialavori, Giuseppe Ferro, Francesca Fusco, Matteo Consalvo, Leandro Chiodi, Francesco Pizzarelli, Alfredo Zuppiroli   +8 more
doaj   +1 more source

Monoaminergic Neuropathology in Alzheimer's disease [PDF]

, 2016
Acknowledgments This work was supported by The Croatian Science Foundation grant. no. IP-2014-09-9730 (“Tau protein hyperphosphorylation, aggregation, and trans-synaptic transfer in Alzheimer’s disease: cerebrospinal fluid analysis and assessment of ...
Bažadona, Danira, Buée, Luc, Delalle, Ivana, Giovanni, Giuseppe Di, Harrington, Charles R., Hof, Patrick R., Jovanov-Milošević, Nataša, Leko, Mirjana Babić, Silva, Rohan de, Wischik, Claude M., Wray, Selina, Šimić, Goran   +11 more
core   +1 more source