Results 91 to 100 of about 770,621 (229)

Inclusion complex of amiodarone hydrochloride with cyclodextrins: preparation, characterization and dissolution rate evaluation

Brazilian Journal of Pharmaceutical Sciences, 2017
This study aimed to improve the water solubility of amiodarone hydrochloride (AMH) via inclusion complexes with β-cyclodextrin, methyl-β-cyclodextrin and 2-hydroxypropyl-β-cyclodextrin.
Alexandre Machado Rubim, Jaqueline Bandeira Rubenick, Marcela Maurer, Luciane Varini Laporta, Clarice Madalena Bueno Rolim   +4 more
doaj   +1 more source

Image_2_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.tif

, 2021
Lifestyle- and genetically induced disorders related to disturbances in cholesterol metabolism have shown the detrimental impact of excessive cholesterol levels on a plethora of pathological processes such as inflammation.
Dimitris Kapsokalyvas (11305455), Dieter Lütjohann (186632), Marit Westerterp (6178532), Tom Houben (3185082), David Leake (10747299), Marion J. J. Gijbels (9501749), Joost J. F. P. Luiken (4390150), Ronit Shiri-Sverdlov (186636), Tulasi Yadati (11145288), Jogchum Plat (302633), Robbin de Kruijf (11305452), Marc van Zandvoort (8349135)   +11 more
core   +1 more source

Validation and Application of an HPLC–UV Method for the Quantification of 3‐O‐Methylquercetin in Nasal Mucosa

ELECTROPHORESIS, Volume 47, Issue 6, Page 479-488, June 2026.
This study improved an HPLC–UV method for quantifying 3‐O‐methylquercetin in porcine nasal mucosa following ICH M10 and ANVISA (Brazil) guidelines, assessing selectivity, linearity, accuracy, precision, and robustness. The method was applied for the first time to evaluate release, permeation, and retention profiles of a nasal formulation.
Jeniffer Viviana Ramirez Hernández, Laura da Silva Machado, Flávia Nathiely Silveira Fachel, Sara Elis Bianchi, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +6 more
wiley   +1 more source

Guideline for the electrospinning of food biomacromolecules

Food Biomacromolecules, Volume 3, Issue 2, Page 406-417, June 2026.
Abstract Electrospinning, an efficient method for producing micro‐ and nanoscale fibers, has undergone a notable resurgence in recent decades since its origin in the early 20th century, largely driven by advances in nanotechnology. Subsequently, it has been extensively applied across various disciplines, including materials science, biomedicine ...
Manjun Kang, Shengyang Ji, Yucheng Zou
wiley   +1 more source

Maternal and Foetal Cardiovascular Effects of the Anaesthetic Alfaxalone in 2-Hydroxypropyl-β-cyclodextrin in the Pregnant Ewe

The Scientific World Journal, 2013
The objective of this study was to determine the pharmacodynamics effects of the anaesthetic alfaxalone in 2-hydroxypropyl-β-cyclodextrin in pregnant sheep after the intravenous injection of a 2 mg/kg weight dose.
Anna Andaluz, Laura Santos, Félix García, Rosa I. Ferrer, Laura Fresno, Xavier Moll   +5 more
doaj   +1 more source

Casein nanoparticles in combination with 2-hydroxypropyl-β-cyclodextrin improves the oral bioavailability of quercetin.

International journal of pharmaceutics, 2019
The aim of this work was to optimize the preparative process of quercetin loaded casein nanoparticles as well as to evaluate the pharmacokinetics of this flavonoid when administered orally in Wistar rats. Nanoparticles were obtained by coacervation after
Rebeca Peñalva, I. Esparza, J. Morales, C. J. González-Navarro, E. Larrañeta, J. Irache   +5 more
semanticscholar   +1 more source

Enhanced Antioxidant, Antiviral, and Anticancer Activities of the Extract of Fermented Egyptian Rice Bran Complexed with Hydroxypropyl-β-cyclodextrin

, 2022
Egyptian rice bran was fermented with baker’s yeast, and released phenolics were extracted with aqueous methanol to give fermented rice bran extract (FRBE).
Khaled A. Nematallah (3103674), Hassan Mohamed El-Said Azzazy (9689346), Hesham I. El-Askary (7826051), Noha Khalil Mahdy (12710055), Sherif Ashraf Fahmy (9689343), Meselhy Ragab Meselhy (10711927)   +5 more
core   +1 more source

Innovative Drug Delivery Systems for the Treatment of Glaucoma

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu, Junzhi Li, Zhenlin Chen, Jinyu Zhang, Siqi Feng, Jiaying Huang, Yawen Chu, Xue Zhou, Wei Wang, Shangsi Chen   +9 more
wiley   +1 more source

Adenosine Encapsulation and Characterization through Layer-by-Layer Assembly of Hydroxypropyl-β-Cyclodextrin and Whey Protein Isolate as Wall Materials

Molecules
Adenosine, as a water-soluble active substance, has various pharmacological effects. This study proposes a layer-by-layer assembly method of composite wall materials, using hydroxypropyl-β-cyclodextrin as the inner wall and whey protein isolate as the ...
Yudie Jin, Suning Zhang
doaj   +1 more source

Physicochemical Characterization and Antioxidant Activity Evaluation of Idebenone/Hydroxypropyl-β-Cyclodextrin Inclusion Complex †

Biomolecules, 2019
Idebenone (IDE) is an antioxidant drug active at the level of the central nervous system (CNS), whose poor water solubility limits its clinical application.
V. Venuti, V. Crupi, B. Fazio, D. Majolino, G. Acri, B. Testagrossa, R. Stancanelli, F. De Gaetano, Agnese Gagliardi, D. Paolino, G. Floresta, V. Pistarà, A. Rescifina, C. Ventura   +13 more
semanticscholar   +1 more source