Results 71 to 80 of about 976,699 (171)

Solubilization of Hydroxypropyl-β-Cyclodextrin on Cholesterol in Aqueous Solution [PDF]

, 2014
Hydroxypropyl-β-Cyclodextrin (HP-β-CD), prepared via reaction of β-Cyclodextrin (β-CD) and propylene oxide (PO), is utilized to research solubilization of HP-β-CD on cholesterol in aqueous solution. HP-β-CD is characterized by Fourier Transform Infrared
Zhou, Lu, Wang, Yali, Li, Lu, Zou, Changjun   +3 more
core  

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, Volume 7, Issue 5, October 2026.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Inclusion complex of amiodarone hydrochloride with cyclodextrins: preparation, characterization and dissolution rate evaluation

Brazilian Journal of Pharmaceutical Sciences, 2017
This study aimed to improve the water solubility of amiodarone hydrochloride (AMH) via inclusion complexes with β-cyclodextrin, methyl-β-cyclodextrin and 2-hydroxypropyl-β-cyclodextrin.
Alexandre Machado Rubim, Jaqueline Bandeira Rubenick, Marcela Maurer, Luciane Varini Laporta, Clarice Madalena Bueno Rolim   +4 more
doaj   +1 more source

Inhibition of leucine‐rich kinase 2 (LRRK2) promotes peripheral axon regeneration via phosphorylation‐network remodelling

British Journal of Pharmacology, Volume 183, Issue 20, Page 6199-6224, October 2026.
Background and Purpose In contrast to neurons in the central nervous system, neurons in the peripheral nervous system can regenerate axons after injury via activation of a pro‐regenerative transcriptional programme. Pathogenic mutations in leucine‐rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson's disease, and several small ...
Eun‐Hae Jang, Eun Mo Yang, Gil Song, Seung Min Park, Harryn Choi, Jaeyong Kim, Chanil Kim, Yunho Gim, Hyuk‐Joo Jeon, Yewon Cho, Jong Bae Park, Eun‐Mi Hur   +11 more
wiley   +1 more source

Maternal and Foetal Cardiovascular Effects of the Anaesthetic Alfaxalone in 2-Hydroxypropyl-β-cyclodextrin in the Pregnant Ewe

The Scientific World Journal, 2013
The objective of this study was to determine the pharmacodynamics effects of the anaesthetic alfaxalone in 2-hydroxypropyl-β-cyclodextrin in pregnant sheep after the intravenous injection of a 2 mg/kg weight dose.
Anna Andaluz, Laura Santos, Félix García, Rosa I. Ferrer, Laura Fresno, Xavier Moll   +5 more
doaj   +1 more source

Molecular Mobility of N‐Acetylgalactosamine‐Modified Cyclodextrins on a Polyrotaxane for Highly Efficient Liver Targeting of Antibody Chimeras and Genome‐Editing Ribonucleoproteins

Advanced Science, Volume 13, Issue 49, 3 September 2026.
Monovalent N‐acetylgalactosamine (GalNAc)‐modified polyrotaxane enables efficient liver targeting by utilizing ligand mobility. The sliding and rotating cyclic components i.e., cyclodextrin in the polyrotaxane dynamically cluster GalNAc moieties, thereby mimicking trivalent interactions with asialoglycoprotein receptors.
Toru Taharabaru, Keiichi Motoyama, Yuting Wen, Zhongxing Zhang, Xuehao Tian, Jun Li, Taishi Higashi   +6 more
wiley   +1 more source

Adenosine Encapsulation and Characterization through Layer-by-Layer Assembly of Hydroxypropyl-β-Cyclodextrin and Whey Protein Isolate as Wall Materials

Molecules
Adenosine, as a water-soluble active substance, has various pharmacological effects. This study proposes a layer-by-layer assembly method of composite wall materials, using hydroxypropyl-β-cyclodextrin as the inner wall and whey protein isolate as the ...
Yudie Jin, Suning Zhang
doaj   +1 more source

Real‐Time Stress Visualization of Hydrogels Enabled by Supramolecularly Switched Stretch‐Induced Phase Separation

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Supramolecular hydrogels enable real‐time visualization of mechanical stress through supramolecular switching mechanotransduction. Adamantane‐modified cellulose functions as a responsive domain that undergoes an on–off transition between hydrated and dehydrated states via reversible β‐cyclodextrin–adamantane complexation and decomplexation.
Sooyeon Noh, Akihide Sugawara, Naoaki Ishihara, Takashi Konishi, Yuki Ueda, Ryuhei Motokawa, Yoshinori Takashima, Hiroshi Uyama   +7 more
wiley   +1 more source

Formulation of Berberine Hydrochloride and Hydroxypropyl-β-Cyclodextrin Inclusion Complex with Enhanced Dissolution and Reduced Bitterness [PDF]

, 2013
Purpose: To prepare and characterize inclusion complex of berberine hydrochloride with hydroxypropyl-β-cyclodextrin in order to achieve enhanced solubility and reduced bitterness of the former.
Shang, Xiaojun, Ma, Suying, Wang, Yong, Yan, Fulin   +3 more
core  

Spectral Characteristics of the Supramolecular Complexes of Polypyrrolic Sensitizers and Cyclodextrin Carriers: Usage in Photodynamic Therapy of Tumors

Acta Medica, 2004
The objective of our work was to describe the photophysical properties (absorption and fluorescence) of the sensitizers TPPS4, ZnTPPS4 a PdTPPS4 and above all the complexes of these sensitizers with cyclodextrin carriers HP-α-CD, HP-β-CD and HP-γ-CD (2 ...
doaj   +1 more source