Results 51 to 60 of about 976,699 (171)

Electrochemical Quantitative Assessment of Labetalol Hydrochloride in Pure Form and Combined Pharmaceutical Formulations

Acta Chimica Slovenica, 2020
This work describes how to utilize the electrochemical technique to determine labetalol hydrochloride (Lab) in pure form and combined pharmaceutical formulation for quality control purposes.
Maissa Yacoub Salem, Nagiba Yehia Hassan, Yasmin Mohamed Fayez, Samah Abd-EL Sabour Mohamed, ENAS Shabaan ALI   +4 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Resveratrol and resveratrol-hydroxypropyl-β-cyclodextrin complex recovered the changes of creatine kinase and Na+, K+-ATPase activities found in the spleen from streptozotocin-induced diabetic rats

, 2019
: Type 1 diabetes (T1D) is the result of the selective destruction of the pancreatic β-cells by T cells of the immune system. Although spleen is a secondary lymphoid organ, it is also involved in the T1D pathogenesis.
GUILHERME M. DO CARMO (7368854), VIRGINIA C. RECH (4681090), LUCIANE R. FEKSA (4681093), MATHEUS D. BALDISSERA (5838365), JANICE L. GIONGO (7368866), NATHANA J. MEZZOMO (4681081), JANAÍNA KOLLING (7368845), LIANA S. FERNANDES (7368857), CLÁUDIA G. PINTO (7368851), JENIFER KOLLING (7368842), VIVIAN S.K. NISHIHIRA (7368848), ANGELA T.S. WYSE (7368869), CLOVIS M.D. WANNMACHER (4681075), ITIANE D. DE FRANCESCHI (4681078), GILBERTO ORENGO (7368860), RODRIGO A. VAUCHER (7368863)   +15 more
core   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

Investigation of the complexation of pyrene and naphthalene with hydroxypropyl-β-cyclodextrin

, 1990
The complexation of the now commercially available chemically modified cyclodextrin hydroxypropyl-β-cyclodextrin with pyrene and naphthalene is compared against the unmodified β-cyclodextrin with the use of fluorescence measurements.
Warner, Isiah M., Ndou, Thilivhali T., Zung, Jonathan B.   +2 more
core   +1 more source

Physiologically Based Pharmacokinetic Modeling to Assess Transporter‐Mediated Drug–Drug Interactions in Support of Labeling Recommendations for Zavegepant Nasal Spray

Clinical Pharmacology &Therapeutics, Volume 120, Issue 5, Page 1402-1413, November 2026.
Zavegepant nasal spray, a calcitonin gene‐related peptide receptor antagonist indicated for acute treatment of migraine with or without aura in adults, is a substrate for organic anion transporting polypeptide 1B3 (OATP1B3), Na+/taurocholate cotransporting polypeptide (NTCP), P‐glycoprotein (P‐gp), and cytochrome P450 3A4 (CYP3A4).
Alice Ke, Ernesto Callegari, Manthena V.S. Varma, Mayur K Ladumor, Chieko Muto, Richard J. Bertz, Hannah M. Jones, Vaishali Sahasrabudhe, Jing Liu   +8 more
wiley   +1 more source

Manufacturing and Assessing the New Orally Disintegrating Tablets, Containing Nimodipine-hydroxypropyl-β-cyclodextrin and Nimodipine-methyl-β-cyclodextrin Inclusion Complexes

Molecules, 2022
The aim of the present study was to manufacture new orally disintegrating tablets containing nimodipine–hydroxypropyl-β-cyclodextrin and nimodipine–methyl-β-cyclodextrin inclusion complexes.
Marian Novac, Adina Magdalena Musuc, Emma Adriana Ozon, Iulian Sarbu, Mirela Adriana Mitu, Adriana Rusu, Daniela Gheorghe, Simona Petrescu, Irina Atkinson, Dumitru Lupuliasa   +9 more
doaj   +1 more source

Green Extraction Coupled With Spray‐Drying Encapsulation Enhances Stability and In Vitro Bioaccessibility of Phoenix dactylifera Seed Bioactives

Food Science &Nutrition, Volume 14, Issue 11, November 2026.
Alginate–xanthan encapsulation of HPAE30 date seed extract improved the retention of phenolic compounds during storage and enhanced their in vitro intestinal bioaccessibility. ABSTRACT The valorization of date seed by‐products as sources of bioactive compounds represents a promising strategy for supporting sustainable and circular food systems.
Olfa Rebai, Faten Raboudi, Malek Ben Temessek, Rafik Gatri, Sami Fattouch   +4 more
wiley   +1 more source

Preparation and characterization of artemether inclusion complexes with hydroxypropyl-β-cyclodextrin [PDF]

, 2017
Purpose: To investigate experimentally the inclusion of artemether into the cavity of  hydroxypropyl-β-cyclodextrin and examine its effect on the solubility and dissolution rate of the drug.Methods: Inclusion complexes of artemether with hydroxypropyl-β ...
Yahaya, Zwanden Sule, Ofokansi, Kenneth C., Bhatia, Pat G., Allagh, Suzane T., Zwanden Sule Yahaya, Kenneth C. Ofokansi, Pat G. Bhatia, Suzane T. Allagh   +7 more
core   +1 more source

Resveratrol and resveratrol-hydroxypropyl-β-cyclodextrin complex recovered the changes of creatine kinase and Na+, K+-ATPase activities found in the spleen from streptozotocin-induced diabetic rats

Anais da Academia Brasileira de Ciências
: Type 1 diabetes (T1D) is the result of the selective destruction of the pancreatic β-cells by T cells of the immune system. Although spleen is a secondary lymphoid organ, it is also involved in the T1D pathogenesis.
JENIFER KOLLING, JANAÍNA KOLLING, ITIANE D. DE FRANCESCHI, VIVIAN S.K. NISHIHIRA, MATHEUS D. BALDISSERA, CLÁUDIA G. PINTO, NATHANA J. MEZZOMO, GUILHERME M. DO CARMO, LUCIANE R. FEKSA, LIANA S. FERNANDES, GILBERTO ORENGO, RODRIGO A. VAUCHER, JANICE L. GIONGO, ANGELA T.S. WYSE, CLOVIS M.D. WANNMACHER, VIRGINIA C. RECH   +15 more
doaj   +1 more source