Results 51 to 60 of about 770,621 (229)

Solubility Enhancement of Myricetin by Inclusion Complexation with Heptakis-O-(2-Hydroxypropyl)-β-Cyclodextrin: A Joint Experimental and Theoretical Study

International Journal of Molecular Sciences, 2020
Four cyclodextrins (CD) including β-cyclodextrin (β-CD), γ-cyclodextrin (γ-CD), heptakis-O-(2-hydroxypropyl)-β-cyclodextrin (HP-β-CD), and heptakis-O-(2, 6-di-O-methyl)-β-cyclodextrin (DM-β-CD) were used as solubilizer to study the solubility enhancement
Dongxu Han, Zhongbao Han, Liyan Liu, Ying Wang, Shi-gang Xin, Hongbo Zhang, Zhan Yu   +6 more
semanticscholar   +1 more source

Synergistic Dual Slip‐Link Toughening of a Water‐Rich Double Network Hydrogel Combining Slide‐Ring and Highly Entangled Networks

Advanced Science, EarlyView.
Two distinct slip‐link mechanisms – the slide‐ring pulley effect and highly entangled chains – are combined in a water‐rich double network hydrogel, achieving synergistic toughening, near‐complete reversibility, and exceptional friction tear resistance at >$>$91 wt.% water.
Subhankar Mandal, Saleh Assadi, Aseem Milind Visal, Ignacio Lorente Montero, Franck J. Vernerey, Carson J. Bruns   +5 more
wiley   +1 more source

Dual 2-Hydroxypropyl-β-Cyclodextrin and 5,10,15,20-Tetrakis (4-Hydroxyphenyl) Porphyrin System as a Novel Chiral-Achiral Selector Complex for Enantioseparation of Aminoalkanol Derivatives with Anticancer Activity in Capillary Electrophoresis

Molecules, 2021
In this study, a complex consisting of 2-hydroxypropyl-β-cyclodextrin and 5,10,15,20-tetrakis (4-hydroxyphenyl) porphyrin, (named dual chiral-achiral selector complex) was used for the determination of two novel potential anticancer agents of (I) and (II)
Błażej Grodner, Mariola Napiórkowska
doaj   +1 more source

Resveratrol and resveratrol-hydroxypropyl-β-cyclodextrin complex recovered the changes of creatine kinase and Na+, K+-ATPase activities found in the spleen from streptozotocin-induced diabetic rats

, 2019
: Type 1 diabetes (T1D) is the result of the selective destruction of the pancreatic β-cells by T cells of the immune system. Although spleen is a secondary lymphoid organ, it is also involved in the T1D pathogenesis.
GUILHERME M. DO CARMO (7368854), VIRGINIA C. RECH (4681090), LUCIANE R. FEKSA (4681093), MATHEUS D. BALDISSERA (5838365), JANICE L. GIONGO (7368866), NATHANA J. MEZZOMO (4681081), JANAÍNA KOLLING (7368845), LIANA S. FERNANDES (7368857), CLÁUDIA G. PINTO (7368851), JENIFER KOLLING (7368842), VIVIAN S.K. NISHIHIRA (7368848), ANGELA T.S. WYSE (7368869), CLOVIS M.D. WANNMACHER (4681075), ITIANE D. DE FRANCESCHI (4681078), GILBERTO ORENGO (7368860), RODRIGO A. VAUCHER (7368863)   +15 more
core   +1 more source

Video_3_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.mov

, 2021
Lifestyle- and genetically induced disorders related to disturbances in cholesterol metabolism have shown the detrimental impact of excessive cholesterol levels on a plethora of pathological processes such as inflammation.
Dimitris Kapsokalyvas (11305455), Dieter Lütjohann (186632), Marit Westerterp (6178532), Tom Houben (3185082), David Leake (10747299), Marion J. J. Gijbels (9501749), Joost J. F. P. Luiken (4390150), Ronit Shiri-Sverdlov (186636), Tulasi Yadati (11145288), Jogchum Plat (302633), Robbin de Kruijf (11305452), Marc van Zandvoort (8349135)   +11 more
core   +1 more source

Molecular Mobility of N‐Acetylgalactosamine‐Modified Cyclodextrins on a Polyrotaxane for Highly Efficient Liver Targeting of Antibody Chimeras and Genome‐Editing Ribonucleoproteins

Advanced Science, EarlyView.
Monovalent N‐acetylgalactosamine (GalNAc)‐modified polyrotaxane enables efficient liver targeting by utilizing ligand mobility. The sliding and rotating cyclic components i.e., cyclodextrin in the polyrotaxane dynamically cluster GalNAc moieties, thereby mimicking trivalent interactions with asialoglycoprotein receptors.
Toru Taharabaru, Keiichi Motoyama, Yuting Wen, Zhongxing Zhang, Xuehao Tian, Jun Li, Taishi Higashi   +6 more
wiley   +1 more source

Video_1_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.mov

, 2021
Lifestyle- and genetically induced disorders related to disturbances in cholesterol metabolism have shown the detrimental impact of excessive cholesterol levels on a plethora of pathological processes such as inflammation.
Dimitris Kapsokalyvas (11305455), Dieter Lütjohann (186632), Marit Westerterp (6178532), Tom Houben (3185082), David Leake (10747299), Marion J. J. Gijbels (9501749), Joost J. F. P. Luiken (4390150), Ronit Shiri-Sverdlov (186636), Tulasi Yadati (11145288), Jogchum Plat (302633), Robbin de Kruijf (11305452), Marc van Zandvoort (8349135)   +11 more
core   +1 more source

Real‐Time Stress Visualization of Hydrogels Enabled by Supramolecularly Switched Stretch‐Induced Phase Separation

Advanced Science, EarlyView.
Supramolecular hydrogels enable real‐time visualization of mechanical stress through supramolecular switching mechanotransduction. Adamantane‐modified cellulose functions as a responsive domain that undergoes an on–off transition between hydrated and dehydrated states via reversible β‐cyclodextrin–adamantane complexation and decomplexation.
Sooyeon Noh, Akihide Sugawara, Naoaki Ishihara, Takashi Konishi, Yuki Ueda, Ryuhei Motokawa, Yoshinori Takashima, Hiroshi Uyama   +7 more
wiley   +1 more source

Image_6_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.tif

, 2021
Lifestyle- and genetically induced disorders related to disturbances in cholesterol metabolism have shown the detrimental impact of excessive cholesterol levels on a plethora of pathological processes such as inflammation.
Dimitris Kapsokalyvas (11305455), Dieter Lütjohann (186632), Marit Westerterp (6178532), Tom Houben (3185082), David Leake (10747299), Marion J. J. Gijbels (9501749), Joost J. F. P. Luiken (4390150), Ronit Shiri-Sverdlov (186636), Tulasi Yadati (11145288), Jogchum Plat (302633), Robbin de Kruijf (11305452), Marc van Zandvoort (8349135)   +11 more
core   +1 more source

Development of immunocompetent models for primary and metastatic ER+ breast cancer

Animal Models and Experimental Medicine, EarlyView.
This study explores syngeneic, immunocompetent models of ER+ breast cancer in 129S6/SvEv mice, using trackable tumor cells to model both primary tumors and metastasis. The models show promise, while also revealing limitations for studying advanced disease and immune interactions.
Devon M. Bull, Jody Hazlett, Emily Schulpen, Sophie Tunnicliffe, Alexander D. McLellan, Anita K. Dunbier   +5 more
wiley   +1 more source