Results 31 to 40 of about 770,621 (229)

Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis [PDF]

, 2011
Human African trypanosomiasis (HAT), or sleeping sickness, results from infection with the protozoan parasites <i>Trypanosoma brucei</i> (<i>T.b.</i>) <i>gambiense</i> or <i>T.b.rhodesiense</i> and is ...
Jones, A., Michael P. Barrett, Peter G E Kennedy, Bradley Barbara, Bradley, Barbara, Barrett, M. P., McCabe Christopher, Peter G. E. Kennedy, Bradley, B., Rodgers, Jean, Gettinby, George, Gettinby George, Kennedy Peter G. E., McCabe, Chris, Amy Jones, Kennedy, Peter G. E., Barrett, Michael P., Michael P Barrett, Kennedy, Peter G.E., George Gettinby, Gibaud, Stephane, Barbara Bradley, McCabe, C., Mccabe, Christopher, Jean Rodgers, Kennedy, P. G. E., Gibaud, S., Stéphane Gibaud, Rodgers, J., Rodgers Jean, Jones Amy, Jones, Amy, Christopher McCabe, Barrett Michael P., Gibaud Stéphane, Gettinby, G.   +35 more
core   +1 more source

Hydroxypropyl-β-cyclodextrin as an effective carrier of curcumin – piperine nutraceutical system with improved enzyme inhibition properties

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
The nutraceutical system of curcumin-piperine in 2-hydroxypropyl-β-cyclodextrin was prepared by using the kneading technique. Interactions between the components of the system were defined by X-ray powder diffraction (XRPD), differential scanning ...
Anna Stasiłowicz, Ewa Tykarska, Kornelia Lewandowska, Maciej Kozak, Andrzej Miklaszewski, Joanna Kobus-Cisowska, Daria Szymanowska, Tomasz Plech, Jacek Jenczyk, Judyta Cielecka-Piontek   +9 more
doaj   +1 more source

Hyperglycosylated LAMP1 is regulated by 2-hydroxypropyl-β-cyclodextrin treatment.

, 2020
A. LAMP1 and β-tubulin Western blot of total cerebellar extract from 7-week-old Npc1+/+ and Npc1−/− mice treated with either 2-hydroxypropyl-β-cyclodextrin (HPβCD) or the vehicle control (PBS) every 3 days starting at 3 weeks of age. B.
Antony Cougnoux (8198772), Anna T. Lyons (8379309), Christopher A. Wassif (125679), Caitlin Sojka (8379306), Niamh X. Cawley (8379303), Elena‐Raluca Nicoli (8379312), Forbes D. Porter (125687)   +6 more
core   +1 more source

Intrathecal 2-hydroxypropyl-β-cyclodextrin decreases neurological disease progression in Niemann-Pick Disease, type C1: an ad-hoc analysis of a non-randomized, open-label, phase 1/2 trial

The Lancet, 2017
Background Niemann-Pick disease, type C1 (NPC1) is a lysosomal storage disorder characterized by progressive neurodegeneration. In preclinical testing 2-hydroxypropyl-β-cyclodextrins (HPβCD) significantly delayed cerebellar Purkinje cell loss, slowed ...
D. Ory, E. Ottinger, N. Farhat, K. King, Xuntian Jiang, L. Weissfeld, E. Berry-Kravis, Cristin D. Davidson, S. Bianconi, Lee Ann Keener, R. Rao, A. Soldatos, Rohini Sidhu, Kimberly A. Walters, Xin Xu, A. Thurm, B. Solomon, W. Pavan, Bernardus N. Machielse Drs, Mark L. Kao, S. Silber, J. McKew, C. Brewer, C. Vite, S. Walkley, C. Austin, F. Porter   +26 more
semanticscholar   +1 more source

Preparation, characterization and in vitro dissolution study of Nitrazepam: Cyclodextrin inclusion complex

Journal of Pharmacy and Bioallied Sciences, 2012
The objectives of this research were to prepare and characterize inclusion complexes of Nitrazepam with Hydroxypropyl-β-cyclodextrin (HPβCD) and Sulfobutyl ether β-cyclodextrin (SBEβCD) to study the effect of complexation on the dissolution rate of ...
J S Patel, R P Patel
doaj   +1 more source

MOESM1 of A promising antitumor activity of evodiamine incorporated in hydroxypropyl-β-cyclodextrin: pro-apoptotic activity in human hepatoma HepG2 cells

, 2016
Additional file 1: Table S1. 1HNMR chemical shift of evodiamine and its inclusion complex in DMSO-d6.
Qiu, Chao, Gao, Li-Na, Yan, Kuo, Yuan-Lu Cui, Zhang, Ye   +4 more
openaire   +1 more source

Video_4_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.mov

, 2021
Lifestyle- and genetically induced disorders related to disturbances in cholesterol metabolism have shown the detrimental impact of excessive cholesterol levels on a plethora of pathological processes such as inflammation.
Dimitris Kapsokalyvas (11305455), Dieter Lütjohann (186632), Marit Westerterp (6178532), Tom Houben (3185082), David Leake (10747299), Marion J. J. Gijbels (9501749), Joost J. F. P. Luiken (4390150), Ronit Shiri-Sverdlov (186636), Tulasi Yadati (11145288), Jogchum Plat (302633), Robbin de Kruijf (11305452), Marc van Zandvoort (8349135)   +11 more
core   +1 more source

Design Strategy for Vulcanization Accelerator of Diphenylguanidine/Cyclodextrin Inclusion Complex for Natural Rubber Latex Foam with Enhancing Performance

Research, 2022
Vulcanization is an essential process to obtain high-performance rubber products. Diphenylguanidine (DPG) is often used as the secondary accelerator in the vulcanization process of natural rubber (NR) latex.
Wang Zhang, Liwei Lin, Junqiang Guo, Ming Wu, Sumin Park, Hang Yao, Sun Ha Paek, Guowang Diao, Yuanzhe Piao   +8 more
doaj   +1 more source

Buccal Resveratrol Delivery System as a Potential New Concept for the Periodontitis Treatment

Pharmaceutics, 2021
The health benefits of resveratrol have been proven to inhibit the development of numerous diseases. A frequent limitation in its use is a low bioavailability stemming from a poor solubility and fast enterohepatic metabolism.
Magdalena Paczkowska-Walendowska, Jakub Dvořák, Natalia Rosiak, Ewa Tykarska, Emilia Szymańska, Katarzyna Winnicka, Marek A. Ruchała, Judyta Cielecka-Piontek   +7 more
doaj   +1 more source

Improvement of stilbenoid production by 2-hydroxypropyl-β-cyclodextrin in white mulberry (Morus alba L.) callus cultures

, 2018
Mulberroside A, oxyresveratrol and resveratrol, commonly found in Morus alba L., are potent anti-aging phytostilbenes. In this study, the effect of the addition of 2-hydroxypropyl-β-cyclodextrin on the levels of phytostilbenes in M.
Tharita Kitisripanya (6006191), Hiroyuki Tanaka (9428), Jukrapun Komaikul (6006188), Kittisak Likhitwitayawuid (2721406), Waraporn Putalun (6006194), Boonchoo Sritularak (4722669)   +5 more
core   +1 more source