Results 31 to 40 of about 976,699 (171)

MOESM1 of A promising antitumor activity of evodiamine incorporated in hydroxypropyl-β-cyclodextrin: pro-apoptotic activity in human hepatoma HepG2 cells

, 2016
Additional file 1: Table S1. 1HNMR chemical shift of evodiamine and its inclusion complex in DMSO-d6.
Qiu, Chao, Gao, Li-Na, Yan, Kuo, Yuan-Lu Cui, Zhang, Ye   +4 more
openaire   +1 more source

Preparation, characterization and in vitro dissolution study of Nitrazepam: Cyclodextrin inclusion complex

Journal of Pharmacy and Bioallied Sciences, 2012
The objectives of this research were to prepare and characterize inclusion complexes of Nitrazepam with Hydroxypropyl-β-cyclodextrin (HPβCD) and Sulfobutyl ether β-cyclodextrin (SBEβCD) to study the effect of complexation on the dissolution rate of ...
J S Patel, R P Patel
doaj   +1 more source

Physiochemical properties of the complex of myricetin and hydroxypropyl-β-cyclodextrin [PDF]

, 2014
Purpose: To improve the hydrophilic property of myricetin by complexing it with hydroxypropyl-β- cyclodextrin (HP-β-CD)Methods: The complexes of myricetin and HP-β-CD were prepared in both water and ethanol.
Zhan, R, Zhang, R, Ma, H, Nan, H
core   +1 more source

Design Strategy for Vulcanization Accelerator of Diphenylguanidine/Cyclodextrin Inclusion Complex for Natural Rubber Latex Foam with Enhancing Performance

Research, 2022
Vulcanization is an essential process to obtain high-performance rubber products. Diphenylguanidine (DPG) is often used as the secondary accelerator in the vulcanization process of natural rubber (NR) latex.
Wang Zhang, Liwei Lin, Junqiang Guo, Ming Wu, Sumin Park, Hang Yao, Sun Ha Paek, Guowang Diao, Yuanzhe Piao   +8 more
doaj   +1 more source

Buccal Resveratrol Delivery System as a Potential New Concept for the Periodontitis Treatment

Pharmaceutics, 2021
The health benefits of resveratrol have been proven to inhibit the development of numerous diseases. A frequent limitation in its use is a low bioavailability stemming from a poor solubility and fast enterohepatic metabolism.
Magdalena Paczkowska-Walendowska, Jakub Dvořák, Natalia Rosiak, Ewa Tykarska, Emilia Szymańska, Katarzyna Winnicka, Marek A. Ruchała, Judyta Cielecka-Piontek   +7 more
doaj   +1 more source

Solubility enhancement of etoricoxib using inclusion complexation with cyclodextrins: formulation of oro dispersible tablets by QbD approach

Journal of Applied Pharmaceutical Research
Background: The work was intended to enhance etoricoxib's solubility and dissolution rate and then develop oro-dispersible tablets for faster onset of action. Methodology: Inclusion complexes (ICs) of the drug were obtained with β-cyclodextrin (β-CD) and
Anjan Kumar Mahapatra, Siddharth Dora, Sanatan Parida, Usharani Bal, Bandana Rani Jena, Madhusmita Lenka   +5 more
doaj   +1 more source

Development and Characterization of Cyclodextrin-Based Nanogels as a New Ibuprofen Cutaneous Delivery System

Pharmaceutics, 2022
Nanogels combine the properties of hydrogels and nanocarrier systems, resulting in very effective drug delivery systems, including for cutaneous applications.
Marzia Cirri, Giulia Nerli, Natascia Mennini, Francesca Maestrelli, Paola Mura   +4 more
doaj   +1 more source

Modulation of Presynaptic Inhibitory Retinal Circuits for Retinal Ganglion Cell Neuroprotection in Glaucoma

Advanced Science, EarlyView.
Ocular hypertension induces early hyperactivity in inner retinal inhibitory circuitry before substantial retinal ganglion cell loss. Sustained pharmacological inhibition of GABAergic/glycinergic neurotransmission and Vgat‐targeted Lin28 expression suppress this hyperactivity and improve RGC survival without reducing intraocular pressure. These findings
Eunji Hong, Chen Lin, Wenjie Long, Ian Kim, Mengwen Xiong, Zuer Wu, Siyuan Rao, Qianbin Wang   +7 more
wiley   +1 more source

Host-Guest Interaction between Herbicide Oxadiargyl and Hydroxypropyl- β -Cyclodextrin

The Scientific World Journal, 2013
In the face of a growing human population and increased urbanization, the demand for pesticides will simply rise. Farmers must escalate yields on increasingly fewer farm acres.
Sofia Benfeito, Tiago Rodrigues, Jorge Garrido, Fernanda Borges, E. Manuela Garrido   +4 more
doaj   +1 more source

Arhgef1 Deletion Disrupts Early Cortical Neurogenesis via PAK1 Overactivation and Causes Motor Dysfunction in Adulthood

Advanced Science, EarlyView.
ARHGEF1 plays a pivotal role in both embryonic cortical neurogenesis and adult motor function. During early development, it governs genesis of deep‐layer cortical neurons by negatively regulating RAC1/CDC42‐PAK1‐Cofilin signaling. In adulthood, ARHGEF1 is important for the maintenance of neuronal morphology and activity in the motor cortex, ensuring ...
Liuren Li, Xuanyue Ma, Zhenyu Ding, Bang Sun, Linglin Liu, Hei Matthew Yip, Wei Wang, Tianying Wu, Yuan Guo, Yinghui Peng, Shiqing Zhang, Jacque Pak Kan Ip, Li Zhang, Keshen Li, Lei Shi   +14 more
wiley   +1 more source