Results 21 to 30 of about 770,621 (229)

Insulin Complexation with Cyclodextrins—A Molecular Modeling Approach

Molecules, 2022
Around 5% of the population of the world is affected with the disease called diabetes mellitus. The main medication of the diabetes is the insulin; the active form is the insulin monomer, which is an instable molecule, because the long storage time, or ...
Pálma Bucur, Ibolya Fülöp, Emese Sipos   +2 more
doaj   +1 more source

A molecular inclusion complex of atenolol with 2-hydroxypropyl-β-cyclodextrin: The production and characterization thereof [PDF]

Journal of the Serbian Chemical Society, 2007
The molecular inclusion complex of atenolol with 2-hydroxypropyl-β-cyclodextrin was synthesized using the coprecipitation method. The complex obtained was characterized by FT-IR, 1H-NMR, 13C-NMR spectroscopy, as well as by DSC and X-ray diffraction ...
Nikolić Vesna, Nikolić Ljubiša, Stanković Mihajlo, Kapor Agneš, Popsavin Mirjana, Cvetković Dragan   +5 more
doaj   +1 more source

Thiolated Hydroxypropyl-β-cyclodextrin: A Potential Multifunctional Excipient for Ocular Drug Delivery

International Journal of Molecular Sciences, 2022
The goal of this study was the design and evaluation of a thiolated cyclodextrin providing high drug solubilizing and mucoadhesive properties for ocular drug delivery.
B. Grassiri, P. Knoll, A. Fabiano, A. Piras, Y. Zambito, A. Bernkop‐Schnürch   +5 more
semanticscholar   +1 more source

Characterization, Stability, and Antibrowning Effects of Oxyresveratrol Cyclodextrin Complexes Combined Use of Hydroxypropyl Methylcellulose

Foods, 2022
Oxyresveratrol (Oxy) has attracted much attention by employing it as an antibrowning agent in fruits and vegetables. In this study, the formation of cyclodextrin (CD) inclusion exhibited a certain protective effect on Oxy oxidative degradation, while ...
Jianfei He, Huai-Yu Chen, Hongbin Chen, Baobei Wang, Fengxian Guo, Zong-Ping Zheng   +5 more
doaj   +1 more source

Thermodynamic properties of hydroxypropyl-β-cyclodextrin/guest interaction: a survey of recent studies

Journal of Thermal Analysis and Calorimetry, 2021
For many years, cyclodextrins (CDs) have been the object of attention for their capability of improving the stability, solubility and bioavailability of numerous molecules of interest, including drugs and nutraceuticals.
Federica D’Aria, Bruno Pagano, C. Giancola   +2 more
semanticscholar   +1 more source

Preparation and Properties of Cyclodextrin Inclusion Complexes of Hyperoside

Molecules, 2022
In order to improve the aqueous solubility and enhance the bioavailability of Hyperoside (Hyp), three inclusion complexes (ICs) of Hyp with 2-hydroxypropyl-β-cyclodextrin (2H-β-CD), β-cyclodextrin (β-CD), and methyl-β-cyclodextrin (M-β-CD) were prepared ...
Xinyu Zhang, Jianqing Su, Xiaoya Wang, Xueyan Wang, Ruixue Liu, Xiang Fu, Ying Li, Jiaojiao Xue, Xiaoli Li, Rui Zhang, Xiuling Chu   +10 more
doaj   +1 more source

Preparation, Properties and Sustained-release Properties of Naringin-loaded Cyclodextrin-polysaccharide-based Gel Spheres

Shipin gongye ke-ji, 2023
In order to make naringin have better water solubility and sustained release performance, hydroxypropyl-β-cyclodextrin was used to have strong adhectogenic ability for naringenin.
Wenjuan ZHANG, Meiyu ZHENG, Shengmin LU, Lu WANG, Yangguang WANG   +4 more
doaj   +1 more source

Inclusion complexes and self-assembled cyclodextrin aggregates for increasing the solubility of benzimidazoles

Brazilian Journal of Pharmaceutical Sciences, 2019
Albendazole and fenbendazole are imidazole derivatives that exhibit broad spectrum activity against parasites, but the low solubility of these drugs considerably reduces their effectiveness. Complexation of albendazole and fenbendazole with cyclodextrins
Leticia Norma Carpentieri Rodrigues, Anna Carollina Moraes Tavares, Beatriz Tavares Ferreira, Adriana Karla Cardoso Amorim Reis, Luciana Morita Katiki   +4 more
doaj   +1 more source

Enhanced Stability and Bioactivity of Natural Anticancer Topoisomerase I Inhibitors through Cyclodextrin Complexation

Pharmaceutics, 2021
The use of cyclodextrins as drug nano-carrier systems for drug delivery is gaining importance in the pharmaceutical industry due to the interesting pharmacokinetic properties of the resulting inclusion complexes.
Víctor González-Ruiz, Ángel Cores, Olmo Martín-Cámara, Karen Orellana, Víctor Cervera-Carrascón, Patrycja Michalska, Ana I. Olives, Rafael León, M. Antonia Martín, J. Carlos Menéndez   +9 more
doaj   +1 more source

INCLUSION COMPLEXES OF NICARDIPINE - HCl FOR ORAL ADMINISTRATION [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2005
Inclusion complexes of nicardipine HCl (NIC) with β-cyclodextrin (β-CD) and hydroxypropyl-β-cyclodextrin (HP-β-CD) were prepared using different methods: coevaporation, kneading and co-precipitation.
G. Atia, S. Ghareeb, M. Issa, H. El-Ghamry, O. Sammour, F. Ghazy   +5 more
doaj   +1 more source