Results 11 to 20 of about 976,699 (171)

Hydroxypropyl-β-cyclodextrin as an effective carrier of curcumin – piperine nutraceutical system with improved enzyme inhibition properties

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
The nutraceutical system of curcumin-piperine in 2-hydroxypropyl-β-cyclodextrin was prepared by using the kneading technique. Interactions between the components of the system were defined by X-ray powder diffraction (XRPD), differential scanning ...
Anna Stasiłowicz   +9 more
doaj   +2 more sources

Formation and Physico-Chemical Evaluation of Nifedipine-hydroxypropyl-β-cyclodextrin and Nifedipine-methyl-β-cyclodextrin: The Development of Orodispersible Tablets

open access: yesPharmaceuticals, 2022
The novelty in this study is the development of new orodispersible tablets containing nifedipine (NIF) as the active ingredient. Initially, the formation of inclusion complexes between nifedipine and two derivatives of beta-cyclodextrin, namely ...
Emma Adriana Ozon   +10 more
doaj   +2 more sources

Enhancement of norfloxacin solubility via inclusion complexation with β-cyclodextrin and its derivative hydroxypropyl-β-cyclodextrin

open access: yesAsian Journal of Pharmaceutical Sciences, 2016
The objectives of the study were to investigate the effects of β-cyclodextrin (βCD) and hydroxypropyl-β-cyclodextrin (HPβCD) on the solubility and dissolution rate of norfloxacin prepared using three different methods, at drug to cyclodextrin weight ...
Gabriel Onn Kit Loh   +2 more
doaj   +2 more sources

Structure of inclusion complex of disulfiram with hydroxypropyl-β-cyclodextrin [PDF]

open access: yesТонкие химические технологии, 2015
Disulfiram is an inhibitor of superoxide dismutase, reduced lipid peroxidation, and can be an effective pharmaceutical substance for the treatment of cataracts.
V. S. Tyukova   +4 more
doaj   +1 more source

Encapsulation Mechanism of Oxyresveratrol by β-Cyclodextrin and Hydroxypropyl-β-Cyclodextrin and Computational Analysis

open access: yesMolecules, 2017
In this study, the encapsulation mechanism of oxyresveratrol and β-cyclodextrin (β-CD) and hydroxypropyl-β-cyclodextrin (HP-β-CD) was studied. As this research shows, oxyresveratrol and two cyclodextrins (CDs) were able to form inclusion complexes in a 1:
Jianfei He   +4 more
doaj   +2 more sources

Space filling of β-cyclodextrin and β-cyclodextrin derivatives by volatile hydrophobic guests

open access: yesBeilstein Journal of Organic Chemistry, 2013
The inclusion of volatile derivatives of benzene and cyclohexane in β-cyclodextrin (β-CD), hydroxypropyl-β-CD, and hydrophilic β-CD-thioethers was investigated by static headspace gas chromatography (HS-GC) and molecular modelling.
Sophie Fourmentin   +3 more
doaj   +2 more sources

Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human african trypanosomiasis [PDF]

open access: yes, 2011
Human African trypanosomiasis (HAT), or sleeping sickness, results from infection with the protozoan parasites Trypanosoma brucei (T.b.) gambiense or T.b.rhodesiense and is invariably fatal if untreated.
McCabe, C.   +7 more
core   +5 more sources

Insulin Complexation with Cyclodextrins—A Molecular Modeling Approach

open access: yesMolecules, 2022
Around 5% of the population of the world is affected with the disease called diabetes mellitus. The main medication of the diabetes is the insulin; the active form is the insulin monomer, which is an instable molecule, because the long storage time, or ...
Pálma Bucur   +2 more
doaj   +1 more source

A molecular inclusion complex of atenolol with 2-hydroxypropyl-β-cyclodextrin: The production and characterization thereof [PDF]

open access: yesJournal of the Serbian Chemical Society, 2007
The molecular inclusion complex of atenolol with 2-hydroxypropyl-β-cyclodextrin was synthesized using the coprecipitation method. The complex obtained was characterized by FT-IR, 1H-NMR, 13C-NMR spectroscopy, as well as by DSC and X-ray diffraction ...
Nikolić Vesna   +5 more
doaj   +1 more source

Characterization, Stability, and Antibrowning Effects of Oxyresveratrol Cyclodextrin Complexes Combined Use of Hydroxypropyl Methylcellulose

open access: yesFoods, 2022
Oxyresveratrol (Oxy) has attracted much attention by employing it as an antibrowning agent in fruits and vegetables. In this study, the formation of cyclodextrin (CD) inclusion exhibited a certain protective effect on Oxy oxidative degradation, while ...
Jianfei He   +5 more
doaj   +1 more source

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