Inclusion complexes of 3-(3-(2-chlorophenyl)prop-2-enoyl)-4-hydroxycoumarin with 2-hydroxypropyl-(-cyclodextrin: solubility and antimicrobial activity [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2022 The aim of the present study is to improve the solubility and antimicrobial activity of 3-(3-(2-chlorophenyl)prop-2-enoyl)-4-hydroxycoumarin by formulating its inclusion complexes with 2-hydroxypropyl-β-cyclodextrin in solution and in solid state.
Jasmina Hadžiabdić +4 more
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Pharmaceutics, 2022 Curcumin is one of the most researched phytochemicals by pharmacologists and formulation scientists to unleash its potential therapeutic benefits and tackle inherent biopharmaceutic problems.
Hamdy Abdelkader +5 more
doaj +1 more source
Improving Lurasidone Hydrochloride's Solubility and Stability by Higher-Order Complex Formation with Hydroxypropyl-β-cyclodextrin. [PDF]
Pharmaceutics, 2023 The biopharmaceutical classification system groups low-solubility drugs into two groups: II and IV, with high and low permeability, respectively. Most of the new drugs developed for common pathologies present solubility issues.
Gamboa-Arancibia ME +6 more
europepmc +2 more sources
An Optimization Procedure for Preparing Aqueous CAR/HP-CD Aggregate Dispersions
Molecules, 2021 β-Carotene is a very important molecule for human health. It finds a large application in the food industry, especially for the development of functional foods and dietary supplements. However, β-carotene is an unstable compound and is sensitive to light,
Enrika Celitan +2 more
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Photostability of piroxicam in the inclusion complex with 2-hydroxypropyl-β-cyclodextrin [PDF]
Hemijska Industrija, 2014 The aim of this work is the protection of piroxicam from photodegradation by forming inclusion complex with 2-hydroxypropyl-β-cyclodextrin. Piroxicam:2-hydroxypropyl-β-cyclodextrin molecular inclusion complex was prepared by coprecipitation ...
Nikolić Vesna D. +6 more
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New Polymorph of β-Cyclodextrin with a Higher Bioavailability
Chemistry, 2023 A new polymorph of anhydrous β-cyclodextrin (polymorph III) was obtained and characterized for the first time using powder X-ray diffraction, infrared spectroscopy, and thermal analysis.
Askar K. Gatiatulin +4 more
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Pharmaceutics, 2022 This study aimed to design and fabricate novel hydroxypropyl-β-cyclodextrin-based hypercrosslinked polymers, called nanosponges, as carriers for anticancer hydrophobic agents and compare them with host–guest complexes of hydroxypropyl-β-cyclodextrin, a ...
Shohreh Peimanfard +5 more
doaj +1 more source
Insulin Complexation with Cyclodextrins—A Molecular Modeling Approach
Molecules, 2022 Around 5% of the population of the world is affected with the disease called diabetes mellitus. The main medication of the diabetes is the insulin; the active form is the insulin monomer, which is an instable molecule, because the long storage time, or ...
Pálma Bucur +2 more
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Supramolecular encapsulation of indigo with β-cyclodextrin and Hydroxypropyl-β-cyclodextrin: a sustainable strategy for enhanced solubility, stability, and reducing agent-free dyeing processes. [PDF]
Bioresour BioprocessIndigo, a ubiquitous vat dye in denim manufacturing, is characterized by its exceptionally low aqueous solubility, necessitating chemical reduction to its leuco form using hazardous agents such as sodium dithionite.
Devi KM, Krishnan N, Yeo CS, Choi KY.
europepmc +2 more sources
A molecular inclusion complex of atenolol with 2-hydroxypropyl-β-cyclodextrin: The production and characterization thereof [PDF]
Journal of the Serbian Chemical Society, 2007 The molecular inclusion complex of atenolol with 2-hydroxypropyl-β-cyclodextrin was synthesized using the coprecipitation method. The complex obtained was characterized by FT-IR, 1H-NMR, 13C-NMR spectroscopy, as well as by DSC and X-ray diffraction ...
Nikolić Vesna +5 more
doaj +1 more source