Results 81 to 90 of about 976,699 (171)

Simvastatin dengan Senyawa Turunan Β-Siklodextrin [PDF]

This study aims to determine the profile of the inclusion complex formed between simvastatin and β-cyclodextrin and its derivatives. To determine the level of stability and determine the solubility level of the inclusion complex formed between ...
Cristy, Devina Wahyu Astaning, Mardiyono, Mardiyono, Harmastuti, Nuraini   +2 more
core   +1 more source

A superior preparation method for daidzein-hydroxypropyl-β-cyclodextrin complexes with improved solubility and dissolution: Supercritical fluid process

Acta Pharmaceutica, 2017
Advantages of the supercritical fluid (SCF) process compared to the conventional solution stirring method (CSSM) in the preparation of daidzein-hydroxypropyl-β-cyclodextrin (HPβCD) complexes were investigated.
Pan Hao, Wang Han-Bing, Yu Yi-Bin, Cheng Bing-Chao, Wang Xiao-Yu, Li Ying   +5 more
doaj   +1 more source

Host-Guest Interactions of Plumbagin with β-Cyclodextrin, Dimethyl-β-Cyclodextrin and Hydroxypropyl-β-Cyclodextrin: Semi-Empirical Quantum Mechanical PM6 and PM7 Methods

, 2018
Molecular interactions of plumbagin inclusion complexes with β-cyclodextrin (BCD), dimethyl--cyclodextrin (MBCD), and hydroxypropyl-β-cyclodextrin (HPBCD) were investigated by semi-empirical, Parameterization Method 6 and 7 (PM6, and PM7) in the aqueous ...
Pisanu Toochinda, Ornin Srihakulung, Apichart Intarapanich, and Luckhana Lawtrakul, Waree Kongprawechnon, Ryo Maezono   +5 more
core   +1 more source

Cyclodextrin/chitosan nanoparticles for oral ovalbumin delivery: Preparation, characterization and intestinal mucosal immunity in mice

Asian Journal of Pharmaceutical Sciences, 2019
A novel oral protein delivery system with enhanced intestinal penetration and improved antigen stability based on chitosan (CS) nanoparticles and antigen-cyclodextrin (CD) inclusion complex was prepared by a precipitation/coacervation method.
Muye He, Chen Zhong, Huibing Hu, Yu Jin, Yanzuo Chen, Kaiyan Lou, Feng Gao   +6 more
doaj   +1 more source

Enzymatic Activity Enhancement of Non-Covalent Modified Superoxide Dismutase and Molecular Docking Analysis

Molecules, 2012
The enzyme activity of superoxide dismutase was improved in the pyrogallol autoxidation system by about 27%, after interaction between hydroxypropyl-β-cyclo- dextrin and superoxide dismutase.
Fa-Jun Song, Yan-Zi Qiu, Zong-Hua Huang
doaj   +1 more source

Development of venetoclax with 2-hydroxypropyl-beta-cyclodextrin inclusion complex for improved bioavailability

Cyclodextrin complexes loaded with venetoclax for improved solubility and therapeutic efficacy as repurposed drug. The venetoclax-cyclodextrin inclusion complex was prepared using kneading method. Primarily in-silico molecular docking study was performed
Smalant Kishor Patil (17823756), Sarvan Maddipatla (17823762), Neelesh Kumar Mehra (17823774), Padakanti Sandeep Chary (17823759), Siva Singothu (11729315), Kuldeep Kumar Bansal (17823771), Y.V Madhavi (17823765), Ekta Pardhi (17823768), Vasundhra Bhandari (162788)   +8 more
core   +1 more source

Gd³⁺:DOTA-Modified 2‑Hydroxypropyl-β-Cyclodextrin/4-Sulfobutyl Ether-β-Cyclodextrin-Based Polyrotaxanes as Long Circulating High Relaxivity MRI Contrast Agents

, 2018
A family of five water-soluble Gd3+:1,4,7,10-tetraazacyclododecane-1,4,7-tetraacetic acid-modified polyrotaxane (PR) magnetic resonance contrast agents bearing mixtures of 2-hydroxypropyl-β-cyclodextrin and 4-sulfobutylether-β-cyclodextrin macrocycles ...
Christopher J. Collins, Yawo A. Mondjinou, Vivek Badwaik, Cheyenne Chaplain (5941724), Joseph Skulsky, Yawo A. Mondjinou (1492195), Asher Demoret, Asher Demoret (5941718), David H. Thompson (1431886), Christopher J. Collins (1492201), Vivek Badwaik (1859206), Bradley P. Loren, Seok-Hee Hyun, Cheyenne Chaplain, Bradley P. Loren (1799845), Joseph Skulsky (5941721), Seok-Hee Hyun (1431880), David H. Thompson   +17 more
core   +1 more source

Impact of Mixed β‑Cyclodextrin Ratios on Pluronic Rotaxanation Efficiency and Product Solubility

, 2015
Water-soluble polyrotaxanes have been prepared under heterogeneous conditions from mixtures of β-cyclodextrin (β-CD), 2-hydroxypropyl-β-cyclodextrin (HP-β-CD), methyl-β-cyclodextrin, or 6-monoazido-β-cyclodextrin with 4-sulfobutyl ether-β-cyclodextrin ...
Christopher J. Collins (1492201), Manxi Xiong (1492204), Pooi Ling Thong (1492198), Yawo A. Mondjinou (1492195), Seok-Hee Hyun (1431880), David H. Thompson (1431886)   +5 more
core   +1 more source

Comparative physicochemical investigation of the inclusion compounds of cyclodextrins with arginine and histidine stereoisomers

Macedonian Journal of Chemistry and Chemical Engineering
The inclusion complexes of α-, β-cyclodextrin and 2-hydroxypropyl-α-cyclodextrin with two amino acid stereoisomers (L-, D-arginine and L-, D-histidine) were studied by using differential scanning calorimetry, thermogravimetry, Fourier transform infrared
Andreea Neacsu
doaj   +1 more source

Lipase catalyzed esterification of free hydroxyl groups of β-cyclodextrin and its derivatives

, 2002
1025-1027Modification of hydroxyl groups of β-cyclodextrin (β-CD) and its methyl and hydroxypropyl derivatives through lipase catalyzed reaction using Rhizomucor miehei (Chirazyme) lipase in n-heptane at 50°C has been carried out with acetic ...
Pattekhan, H H, S. Divakar, H. H. Pattekhan, Divakar, S   +3 more
core   +1 more source