Results 171 to 180 of about 97,911 (299)

Podcast‐induced reflex seizures: A unique trigger

Epileptic Disorders, EarlyView.
David W. Cao, Roberto Gonzalez, Irfan S. Sheikh, Melissa Huynh Mabry   +3 more
wiley   +1 more source

Asprosin as a Potential Link Between Vascular Inflammation and Disease Activity in Behçet's Disease

Journal of Clinical Laboratory Analysis, EarlyView.
Serum asprosin levels are significantly elevated in patients with Behçet's disease compared to healthy controls. Asprosin concentrations increase progressively with disease activity and are strongly associated with vascular involvement and uveitis, suggesting a potential role as a biomarker of vascular inflammation and disease severity.
Zeynep Kaya, Mesude Seda Aydogdu, Cihat Ucar, Mehmet Nur Kaya, Sezgin Zontul, Elif Inanc, Servet Yolbas   +6 more
wiley   +1 more source

PTSD and Audio Vestibular Symptoms: A Two-Way Street Driven by the Amygdala? A Speculative Hypothesis. [PDF]

Brain Sci
Roccamatisi D, Indovina I, De Luca P, Ralli M, Kaski D, Di Stadio A.   +5 more
europepmc   +1 more source

Posttraumatic stress, perceived hostile intention and reactions to peer provocation: A longitudinal study in US inner‐city youth

JCPP Advances, EarlyView.
This longitudinal study examined how posttraumatic stress (PTS) affects adolescents' responses to peer provocation, using self‐reports from 2014 predominantly ethnic minority youth aged 12–14. Path analysis showed that higher PTS was linked to more aggression, greater perceived hostility, and a lower tendency to ignore provocation, especially among ...
Vladislav Ruchkin, Andrew Stickley, Mary Schwab‐Stone, Johan Isaksson   +3 more
wiley   +1 more source

Ccl5 establishes an autocrine high-grade glioma growth regulatory circuit critical for mesenchymal glioblastoma survival [PDF]

, 2017
Gutmann, David H, Hambardzumyan, Dolores, Ma, Yu, Pan, Yuan, Smithson, Laura J   +4 more
core   +2 more sources

Surveying immune and inflammatory alterations in periodontitis among individuals with Down syndrome: A preliminary cross‐sectional study

Journal of Periodontology, EarlyView.
Abstract Background Individuals with Down syndrome (DS) are particularly vulnerable to early‐onset and rapidly progressing periodontitis, yet the local immune‐inflammatory alterations that contribute to this susceptibility are not fully understood. This study aimed to characterize cytokine profiles in gingival crevicular fluid (GCF) from individuals ...
Leticia Helena Theodoro, João Victor Soares Rodrigues, Marta A. A. Nuernberg, Pedro Henrique Petrilli, Mabelle de Freitas Monteiro, Valdir Gouveia Garcia, Rafael Scaf de Molon, Renato Correa Viana Casarin   +7 more
wiley   +1 more source

Protein kinases regulate hyperactivated motility of human sperm

Chinese Medical Journal, 2021
Ya-Yan Wang, Pei-Bei Sun, Kun Li, Tian Gao, Dong-Wang Zheng, Fang-Ping Wu, A-juan Liu, Ya Ni, Peng Lyu   +8 more
openaire   +3 more sources

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

Med Research, EarlyView.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Hyperactivation of mTORC1 signaling mediates folliculin deficiency-induced pulmonary cyst formation in Birt-Hogg-Dubé syndrome. [PDF]

J Clin Invest
Cao K, Chen H, Chu L, Wang HJ, Zhang J, Luo Y, Chiu J, Khabibullin D, Alesi N, Thornton ME, Grubbs BH, Ataya A, Gupta N, McCormack FX, Wikenheiser-Brokamp KA, Henske EP, Shi W.   +16 more
europepmc   +1 more source

Ex Vivo LRRK2 Activation in Asian G2385R and R1628P Variant Carriers and Idiopathic Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Leucine‐rich repeat kinase 2 (LRRK2) kinase inhibition is a promising therapeutic strategy for Parkinson's disease (PD), but the functional impact of Asian‐prevalent LRRK2 p.G2385R and p.R1628P variants remains unclear. Robust patient stratification and target engagement markers are needed for global LRRK2‐targeted trials ...
Tzi Shin Toh, Lei Cheng Lit, Shen‐Yang Lim, Jia Wei Hor, Choey Yee Lew, Anis Nadhirah Khairul Anuar, Yi Wen Tay, Kirsten Black, Jia Lun Lim, Jannah Zulkefli, Kai Shi Lim, Hans Xing Ding, Shalini Padmanabhan, Azlina Ahmad‐Annuar, Eng King Tan, Dario R. Alessi, Esther Sammler, Ai Huey Tan   +17 more
wiley   +1 more source