Results 181 to 190 of about 65,627 (261)

The NF-κB Signalling Pathway: Mechanisms, Consequences and Therapeutic Targets. [PDF]

J Cell Mol Med
Pourdad B, Pourdad A.
europepmc   +1 more source

Hyperactivation and Tyrosine Phosphorylation of Cryopreserved Stallion Spermatozoa in Relation to Conventional In Vitro Fertilization Blastocyst Production

Andrology, EarlyView.
ABSTRACT Background Challenges in establishing clinical conventional in vitro fertilization (IVF) in horses include variation in sperm and oocyte quality, which can be affected by mare age. Extended preincubation of stallion spermatozoa has resulted in successful IVF.
Raul A. Gonzalez‐Castro, Carolina C. Porflidt, Alexandra L. Ash, Jacobo S. Rodriguez, Perla D. Fleury, Edward L. Squires, Elaine M. Carnevale   +6 more
wiley   +1 more source

PPP2R3C serves as a negative regulator associated with reduced T cell hyperactivation and renal protection in lupus. [PDF]

Clin Transl Med
Fang X, Qin Y, Tao J, Zhou Z, Cai M, Zhang H, Li X, Li X, Chen Z.   +8 more
europepmc   +1 more source

Improving ARTs: Microfluidics as a Tool for Sperm Selection

Andrology, EarlyView.
ABSTRACT Sperm selection is a critical step in assisted reproductive technology (ART), as sperm quality directly influences embryo quality. In vivo, the female reproductive tract imposes several physical and physiological barriers that favors only the most optimal spermatozoa reaching the fertilization site.
A. Pérez‐Gómez, A. Urriés, J. L. de Pablo, L. Serrano‐Ramón, S. Sanchez, R. Herrer, J. M. Morrell, C. Malo   +7 more
wiley   +1 more source

Hyperactivation of mTORC1 signaling mediates folliculin deficiency-induced pulmonary cyst formation in Birt-Hogg-Dubé syndrome. [PDF]

J Clin Invest
Cao K, Chen H, Chu L, Wang HJ, Zhang J, Luo Y, Chiu J, Khabibullin D, Alesi N, Thornton ME, Grubbs BH, Ataya A, Gupta N, McCormack FX, Wikenheiser-Brokamp KA, Henske EP, Shi W.   +16 more
europepmc   +1 more source

Screen Time Exposure and Children's and Adolescents' Health. A Position Paper from the European Academy of Paediatrics (EAP) and European Confederation of Primary Care Paediatricians (ECPCP)

Acta Paediatrica, EarlyView.
ABSTRACT Aim This position paper aims to synthesize current evidence on the effects of screen exposure on children's and adolescents' physical, mental and social health, critically review existing international and European guidelines, and propose coordinated, harmonized and age‐appropriate recommendations for policymakers, paediatric societies ...
Lorenza Onorati, Grigorios Papantoniou, Berthold Koletzko, Artur Mazur, Dominique Kyriaki Karafyllidou, Eugenio Baraldi, Laura Reali   +6 more
wiley   +1 more source

Polyethylene glycol loxenatide reduces NETosis and immunofluorescence hyperactivation in Behçet's disease. [PDF]

Eur J Med Res
Jia F, Wu X, Sheng H.
europepmc   +1 more source

Shame as a mediator of the association of childhood emotional abuse with aversive cognitive perseveration in adults

British Journal of Psychology, EarlyView.
Abstract Childhood emotional abuse (CEA) has been linked to response‐focused emotion regulation in adulthood. However, the underlying mechanisms remain unexplored. This pre‐registered study examined whether shame mediates the association between CEA history and aversive cognitive perseveration (ACP), including brooding rumination, experiential ...
Mohammadali Amini‐Tehrani, Michael Weinborn, Kenneth Sim, Jeneva L. Ohan, Kristin Naragon‐Gainey   +4 more
wiley   +1 more source

Nucleotide metabolism reprogramming in obesity-associated cardiovascular inflammation: a new perspective. [PDF]

Front Immunol
Qian T, Zhang M, Liu Y, Guo D, Jin J.
europepmc   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source