Results 211 to 220 of about 9,958 (250)

Cortical hyperactivation at low working memory load: A primary processing abnormality in people with schizophrenia? [PDF]

NeuroImage: Clinical, 2020
A frequent finding when studying substrates of working memory (WM) deficits in people with schizophrenia (PSZ) is task-induced hyperactivation relative to healthy control subjects (HCS) when WM load is low.
Britta Hahn, Gi-Yeul Bae, Benjamin M Robinson   +2 more
exaly   +2 more sources

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Pentoxifylline stimulates hyperactivation in human spermatozoa

Human Reproduction, 1993
The effects of pentoxifylline on the movement characteristics of human spermatozoa incubated under capacitating conditions were examined using automated digital image analysis. Washed spermatozoa from cryopreserved and fresh normozoospermic, and fresh oligozoospermic semen were incubated in the presence of pentoxifylline (3.6 mM) for 30 min.
V J, Kay, J R, Coutts, L, Robertson
openaire   +2 more sources

Hyperactivated Motility in Sperm

Journal of Andrology, 1996
The functions of hyperactivation may fit together to create the following scenario. Sperm that enter the oviduct bind to the mucosal epithelium. Near the time of ovulation, hyperactivation helps them to detach from the epithelium, escape mucosal pockets, and move through oviductal mucus.
openaire   +2 more sources

Hyperactivated mitophagy in hematopoietic stem cells

Nature Immunology, 2017
Damaged mitochondria are targeted for mitophagy by the Pink–Parkin ubiquitin pathway. The mitochondrial ATPase Atad3a prevents aberrant activation of Pink and protects hematopoietic stem cells.
Chong, Yang, Toshio, Suda
openaire   +2 more sources

Cisplatin Resistance Associated with PARP Hyperactivation

Cancer Research, 2013
Abstract Non–small cell lung carcinoma patients are frequently treated with cisplatin (CDDP), most often yielding temporary clinical responses. Here, we show that PARP1 is highly expressed and constitutively hyperactivated in a majority of human CDDP-resistant cancer cells of distinct histologic origin.
Michels, J., Vitale, I., Galluzzi, L., Adam, J., Olaussen, K., Kepp, O., Senovilla, L., Talhaoui, I., Guegan, J., Enot, D., Talbot, M., Robin, A., Girard, Pascal, Orear, C., Lissa, D., Sukkurwala, A., Garcia, P., Behnam-Motlagh, P., Kohno, K., Wu, G., Brenner, Catherine, Dessen, P., Saparbaev, M., Soria, J.-C., Castedo, M., Kroemer, G.   +25 more
openaire   +3 more sources

Dissecting hyperactivation in AD

Science, 2019
Neurodegeneration Progressive accumulation of amyloid β (Aβ) in the brain is a defining feature of Alzheimer's disease (AD). At late stages of AD, pathological Aβ accumulations cause neurodegeneration and cell death. However, neuronal dysfunction, consisting of an excessively increased activity in a fraction of brain neurons, already occurs in early ...
openaire   +1 more source

Kinematic definition of ram sperm hyperactivation

Reproduction, Fertility and Development, 1999
Although it is known that ram spermatozoa exhibit hyperactivated motility under capacitating conditions, quantitative analyses of the head and flagellar movement of washed ram spermatozoa have not been published. Motile spermatozoa were recovered from semen by swim-up into HSOF medium, and their movement in 30-µm-deep chambers was videorecorded ...
S T, Mortimer, W M, Maxwell
openaire   +2 more sources

Hyperactivation of mammalian sperm.

Cellular and molecular biology (Noisy-le-Grand, France), 2004
Mammalian sperm commonly show hyperactivated motility just before fertilization. The movement of hyperactivated sperm appears different in fluids of different viscosity and elasticity and in different species, but basically it involves an increase in flagellar bend amplitude and, usually, beat asymmetry.
S S, Suarez, H C, Ho
openaire   +1 more source

156 Effect of human tubal fluid medium and hyperactivation inducers on stallion sperm capacitation and hyperactivation

Reproduction, Fertility and Development, 2018
Conventional IVF has not yet been implemented in the equine species. One of the main reasons has been the inability to develop a culture medium and incubation conditions supporting high levels of stallion sperm capacitation and hyperactivation in vitro.
R. Felmer, C. Arroyo-Salvo, F. Fuentes, P. Cabrera, F. Treulen, M. Silva, M. E. Arias   +6 more
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[CatSper and sperm hyperactivation].

Zhonghua nan ke xue = National journal of andrology, 2007
Elevation of sperm Ca2+ seems to be responsible for an asymmetric form of motility called hyperactivation, which is first seen near the time of fertilization. CatSper family proteins are putative cation channels expressed exclusively in the membranes of the sperm flagellum.
Li-juan, Kong, Yuan-yuan, Yang, Gen-lin, Wang   +2 more
openaire   +1 more source