Results 41 to 50 of about 625 (114)

The IL‐10/IL‐6 Ratio and the Risk Score: Two Cytokines‐Based Predictors for Malignancy‐Associated Hemophagocytic Lymphohistiocytosis in Adults (M‐HLHa)

American Journal of Hematology, Volume 101, Issue 9, Page 2214-2224, September 2026.
ABSTRACT The predictive value of cytokines (CK) for malignancy‐associated adult hemophagocytic lymphohistiocytosis (M‐HLHa) remains uncertain. We evaluated a cytokine‐based Risk Score (RS) and the IL‐10/IL‐6 Ratio to predict M‐HLHa. Adult patients (n = 112) from the French HLH cohort (NCT02113917) with complete data for nine key HLH related CK measured
Coralie Bloch, Stephanie Chhun, Nanthara Sritharan, Marine Gil, Raphael Lhote, Marouane Boubaya, Olivier Lambotte, David Launay, Claire Larroche, Estibaliz Lazaro, Francois Liffermann, Marc Michel, Jean‐Marie Michot, Pierre Morel, Louis Terriou, Geoffrey Urbansk, Jean‐Francois Viallard, Morgane Cheminant, Felipe Suarez, Yves Lepelletier, Geneviève de Saint Basile, Olivier Hermine, the French HLH Study Group, Coralie Bloch, Jean Philippe Jais, Francois Liffermann, Pierre Morel, Morgane Cheminant, Felipe Suarez, Olivier Hermine, Fabrice Bonnet, Pascal Godemer, Damaj Gandhi, Olivier Fain, Olivier Lambotte, David Launay, Louis Terriou, Claire Larroche, Estibaliz Lazaro, Jean‐Francois Viallard, Francois Liffermann, Olivier Lortholary, Marc Michel, Jean‐Marie Michot, Pierre Morel, Frederic Pene, Antoinette Perlat, Geoffrey Urbanski   +47 more
wiley   +1 more source

Clinical and Laboratory Characteristics and Differential Diagnosis between Secondary Hemophagocytic Syndrome and Sepsis

Клиническая онкогематология, 2019
Background. Secondary hemophagocytic syndrome (SHPS) and sepsis, although very similar in their clinical manifestations and laboratory parameters, essentially differ in terms of methods of their treatment.
Vsevolod Gennad’evich Potapenko, M. Yu. Pervakova, A. V. Titov, O. V. Goloshchapov, S. V. Lapin, E. A. Surkov, A. V. Klimovich, O. P. Mironova, N. N. Petrova, N. Yu. Chernookaya, E. V. Karyagina, N. V. Skorobogatova, E. S. Pavlyuchenko, E. A. Karev, N. A. Potikhonova, V. A. Dubkova, A. Yu. Kaskov, A. V. Rysev, T. G. Kulibaba, N. V. Medvedeva   +19 more
doaj   +1 more source

Is there a connection between iron exchange and COVID-19?

Вестник анестезиологии и реаниматологии, 2020
The review analyzes possible epidemiological and molecular mechanisms responsible for hyperinflammation in patients with the severe course of COVID-19.Results: it highlights the similarities between this condition and hyperferritinemic syndrome which ...
Yu. P. Orlov, V. T. Dolgikh, E. I. Vereschagin, V. N. Lukach, N. V. Govorova, V. N. Kokhno, A. N. Shmakov, Ya. N. Patyukov   +7 more
doaj   +1 more source

Pediatric scrub typhus complicated by cytokine storm, hyperferritinemia, and cerebral infarcts: A case report

Journal of Pediatric Critical Care, 2022
Hyperferritinemia has been associated with increased mortality in severe sepsis and also described with scrub typhus. We describe a case of a 10-year-old child with acute febrile illness, altered sensorium, seizures, and left hemiparesis, along with ...
Ajay Gupta, Vidya B Ghosh, Anil K Singh
doaj   +1 more source

A Multifaceted Interplay Among Hemophagocytosis, Interleukin‐18, and Type I Interferon Distinguishes Still Disease From Other Autoinflammatory Diseases

Arthritis &Rheumatology, Volume 78, Issue 9, Page 1961-1974, September 2026.
Objective The unknown pathophysiology and the lack of specific features for systemic juvenile idiopathic arthritis and adult‐onset Still disease (collectively known as Still disease; SD) delay diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G. B. Grashof, Laurie Vaillant, Renske J. H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +16 more
wiley   +1 more source

A clinical predictive score of high liver iron content in metabolic hyperferritinemia: a retrospective cohort pilot study

BMC Gastroenterology
Background In metabolic hyperferritinemia, most patients do not require bloodletting as the liver iron content is mildly increased. We aimed to develop a clinical predictive score of high liver iron content in metabolic hyperferritinemia to guide the ...
Mohamed Lotfi Boughzala, Bruno Pereira, Marc Ruivard, Hervé Lobbes   +3 more
doaj   +1 more source

Síndrome hereditária hiperferritinemia-catarata: caso clínico

Acta Médica Portuguesa
Hereditary hyperferritinemia-cataract syndrome is an autosomal dominant genetic disorder that is characterized by high serum ferritin levels without iron overload and early-onset cataracts.
Carolina Fernandes, Cláudia Diogo, Cristiana Malhó, Filipa Alçada, Sónia Campos   +4 more
doaj   +1 more source

Hippocampal Volume Mediates the Association Between Serum Ferritin and Cognition in Non‐Dialysis End‐Stage Renal Disease Patients

Brain and Behavior, Volume 16, Issue 9, September 2026.
Cognitive impairment is a prevalent neurological complication of end‐stage renal disease (ESRD), yet the neuroanatomical pathway linking iron overload to cognitive decline remains unclear. This study enrolled 50 nondialysis ESRD patients and 48 demographically matched healthy controls, all of whom underwent 3.0T structural MRI for voxel‐based ...
Jingjing Si, Minghua Zhu, Mingzhe Dai
wiley   +1 more source

Association of Ferritin Levels With Cytokine Release Syndrome in CAR T‐Cell Therapy: A Systematic Review and Meta‐Analysis

Cancer Medicine, Volume 15, Issue 9, September 2026.
CAR T‐cell infusion can induce production of excessive cytokines resulting in cytokine release syndrome (CRS). Ferritin is elevated in severe CRS and both pre‐ and post‐infusion levels are associated with poor survival. ABSTRACT Background Ferritin elevation is frequently observed during cytokine release syndrome (CRS) following CAR T‐cell therapy ...
Ranjit Sah, Abhinav Bhattarai, Sangam Shah, Rachana Mehta, Sanjit Sah, Zeeshan Solangi, George P. Sorescu   +6 more
wiley   +1 more source

Vasopressor‐Associated Limb Ischemia Resulting in Quadruple Amputation in Suspected Septic Shock

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Vasopressor‐associated limb ischemia (VALI) is a rare but devastating complication of vasopressor therapy in septic shock. This case shows catastrophic four‐limb amputation in a 26‐year‐old obese male with suspected septic shock. This case illustrates the complex interplay between prolonged high‐dose vasopressor therapy, morbid obesity, and ...
Muni Rubens, Venkataraghavan Ramamoorthy, Krimal Shah, Ashley Rodriguez, Brian Murillo, Karelis Lopez Muniz, Anshul Saxena, Peter McGranaghan, Tina Sanjar   +8 more
wiley   +1 more source