Results 31 to 40 of about 4,383 (214)
Molecules, 2020 St. John’s wort (Hypericum perforatum L.) is a medicinal plant that alleviates depression and other disorders due to its abundance of active ingredients. Hyperforin, rutin, and melatonin are the main active, and important, ingredients in St.
Chia-Hung Kuo +4 more
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In silico study of the toxicity of hyperforin and its metabolites [PDF]
Pharmacia, 2023 St. John’s wort is a medicinal herb well-known for its antidepressant, anti-inflammatory, antimycotic, and wound-healing properties. Hyperforin, the major phloroglucinol derivative, has been implicated as one of the main contributors to these therapeutic
Ivelin Iliev +3 more
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The Total Synthesis of Hyperforin [PDF]
Synlett, 2016 Hyperforin has remained a popular and challenging synthetic target since its isolation over forty years ago. As a result, numerous synthetic strategies and ring-forming reactions have been developed to address its formidable molecular architecture. Herein we describe our contributions to this area resulting in a ten-step synthetic pathway enabled by a ...
Thomas Maimone, Chi Ting
openaire +1 more source
Abnormal expression, localization and interaction of canonical transient receptor potential ion channels in human breast cancer cell lines and tissues: a potential target for breast cancer diagnosis and therapy [PDF]
, 2009 Background Ca2+ is known to be involved in a number of metastatic processes including motility and proliferation which can result in store-depletion of Ca2+.
Christopher Palmer +3 more
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Frontiers in Cellular Neuroscience, 2019 Hyperforin has been shown to be capable of promoting angiogenesis and functional recovery after ischemic stroke in our previous study. However, the exact mechanisms involved are not fully elucidated.
Hua Yao +16 more
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The antidepressant hyperforin increases the phosphorylation of CREB and the expression of TrkB in a tissue-specific manner. [PDF]
, 2012 International audienceHyperforin is one of the main bioactive compounds that underlie the antidepressant actions of the medicinal plant Hypericum perforatum (St. John's wort).
Abrous, Djoher Nora +5 more
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BIOLOGICAL ACTIVITY OF HYPERICUM PERFORATUM L. (HYPERICACEAE): A REVIEW
Фармация и фармакология (Пятигорск), 2021 Hypericum perforatum L. (St. John's wort) is a medicinal plant that has been intensivly studied by clinicians, pharmacologists, and chemists. It has resulted in the publication of both original articles and a number of, reviews devoted to the general ...
A. L. Budantsev +3 more
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Lavender oil-potent anxiolytic properties via modulating voltage dependent calcium channels [PDF]
, 2013 Recent clinical data support the clinical use of oral lavender oil in patients suffering from subsyndromal anxiety. We identified the molecular mechanism of action that will alter the perception of lavender oil as a nonspecific ingredient of aromatherapy
Klugbauer, Norbert +5 more
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Hyperforin Potentiates Antidepressant-Like Activity of Lanicemine in Mice
Frontiers in Molecular Neuroscience, 2018 N-methyl-D-aspartate receptor (NMDAR) modulators induce rapid and sustained antidepressant like-activity in rodents through a molecular mechanism of action that involves the activation of Ca2+ dependent signaling pathways.
Bartłomiej Pochwat +11 more
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Antioxidants, 2020 In this paper we review the mechanisms of the antitumor effects of Hypericum perforatum L. (St. John’s wort, SJW) and its main active component hyperforin (HPF).
Marta Menegazzi +2 more
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