Results 31 to 40 of about 2,864 (178)
Bigel formulations of St. John’s wort extract in wound healing: toxicological aspects
Biotechnology & Biotechnological Equipment, 2023 This study aimed to investigate the toxicological profile of hyperforin (HP) in silico and to assess it in vivo after topical application of an HP-rich St. John’s wort (SJW) extract. The former analysis predicted low toxicity because of HP’s inability to
Yoana Sotirova +8 more
doaj +1 more source
Hyperforin induces senescence in endothelial and tumor cells [PDF]
, 2017 The limited life span of non-transformed somatic cells is largely due to the induction of replicative (telomere dependent) or premature (telomere independent)senescence.
Sabouri Khameneh, Haniyeh
core +1 more source
Gels, 2023 This study aimed to develop a semisolid vehicle for topical delivery of nanoencapsulated St. John’s wort (SJW) extract, rich in hyperforin (HP), and explore its wound-healing potential.
Yoana Sotirova +9 more
doaj +1 more source
Hyperforin: A lead for antidepressants
International Journal of Health Research, 2010 Depression is a complex but treatable disorder if diagnosed appropriately. However, despite the advances in the understanding of the molecular basis of this disorder and the vast range of medication, psychotherapy and electroconvulsive therapy, very safe and effective drug to treat this disease is still being sought.
Hussain, S, Ansari, Z, Arif, M
openaire +3 more sources
Zentrale cholinerge Wirkungen von Hyperforin, einem Inhaltsstoff des Johanniskrauts [PDF]
, 2002 Die vorliegende Arbeit beschreibt die Wirkung von Hyperforin, einem Johanniskraut-Inhaltsstoff, auf das zentrale cholinerge System. Da der HACU Na+-abhängig operiert und Hyperforin den transmembranären Na+-Gradienten verringert, wurde an Rattenkortex ...
Buchholzer, Marie-Luise
core +2 more sources
In vitro antitumor activity of Hyperforin in A375, FO1 and SKMEL-28 human melanoma cell lines
, 2022 noneGli effetti antitumorali dell'iperforina rispetto al suo uso più tradizionale come antidepressivo sono stati appena esplorati nelle cellule di melanoma.
ADDO, SOLOMON SAFORO
core
Anticancer and antibacterial activity of hyperforin and its derivatives
, 2014 Hyperforin is a natural phloroglucinol that has been known for the treatment of depression. Hyperforin displays also antibacterial, antiproliferant and antiangiogenic activity.
Rosato, Antonio +7 more
core +4 more sources
L., Crantz., L. and L.: Phytochemical and Morphological Studies
Natural Product Communications, 2006 Four species of Hypericum growing in Italy were characterized morphologically and chemically: Hypericum perforatum L., H. maculatum Crantz., H. calycinum L. and H. pulchrum L. The composition of secondary metabolites (phloroglucinols, naphthodianthrones,
Gelsomina Fico +3 more
doaj +1 more source
Antioxidants, 2020 In this paper we review the mechanisms of the antitumor effects of Hypericum perforatum L. (St. John’s wort, SJW) and its main active component hyperforin (HPF).
Marta Menegazzi +2 more
doaj +1 more source
Frontiers in Pharmacology, 2022 When confronted with non-psychotic mental disorders, pregnant women often refrain from using synthetic drugs and resort to herbal medicines such as St. John’s wort, California poppy, valerian, lavender, and hops. Nevertheless, these herbal medicines have
Deborah Spiess +6 more
doaj +1 more source