Results 51 to 60 of about 4,383 (214)

Neurocognitive improvement through plant food bioactives: A particular approach to Alzheimer's disease [PDF]

, 2017
Alzheimer’s disease (AD) is currently one of the most prevalent neurodegenerative disorders, directly related to increasing rates of morbidity and autonomy impairment between worldwide citizens. Social and demographical changes are direct contributors;
Ferreira, Isabel C.F.R., Martins, Natália   +1 more
core   +1 more source

Variation of Bioactive Secondary Metabolites in Turra from Wild Populations of Turkey

Natural Product Communications, 2008
The present study was conducted to determine the variation in the content of hyperforin, hypericin and pseudohypericin in Hypericum triquetrifolium Turra growing wild in four locations of Turkey.
Necdet Çamaş, Jolita Radušienė, Ali Kemal Ayan, Cüneyt Çırak, Valdimaras Janulis, Liudas Ivanauskas   +5 more
doaj   +1 more source

In vivo activity and pharmacokinetics of nemorosone on pancreatic cancer xenografts. [PDF]

PLoS ONE, 2013
Pancreatic cancer is one of the leading cancer-related causes of death in the western world with an urgent need for new treatment strategies. Recently, hyperforin and nemorosone have been described as promising anti-cancer lead compounds.
Robert J Wolf, Ralf A Hilger, Jörg D Hoheisel, Jens Werner, Frank Holtrup   +4 more
doaj   +1 more source

Nanoenabled Phytochemical Mining: Gold Nanoparticle‐Mediated Recovery of Low‐Polar Secondary Metabolites From Plant Extract

Small Structures, Volume 7, Issue 3, March 2026.
Green‐synthesized gold nanoparticles serve as tunable nanoadsorbents for selectively enriching low‐polarity secondary metabolites from Hypericum perforatum extracts. Structure‐ and polarity‐dependent interactions, optimized by solvent composition and incubation time, enable efficient recovery of phloroglucinols and xanthones for phytochemical ...
Matam Pradeep, Suman Kalyan Sahoo, Dibyendu Mondal, Gregory Franklin   +3 more
wiley   +1 more source

Catalytic enantioselective synthesis of quaternary carbon stereocentres. [PDF]

, 2014
Quaternary carbon stereocentres-carbon atoms to which four distinct carbon substituents are attached-are common features of molecules found in nature. However, before recent advances in chemical catalysis, there were few methods of constructing single ...
Overman, Larry E, Quasdorf, Kyle W
core  

Characterizing the Metabolic Fingerprint and Anti-inflammatory Activity of Hypericum gentianoides [PDF]

, 2008
In this paper we characterize the metabolic fingerprint and first reported anti-inflammatory activity of Hypericum gentianoides. H. gentianoides has a history of medical use by Native Americans, but it has been studied very little for biological activity.
Birt, Diane, Birt, Diane, Hammer, Kimberly, Hillwig, Matthew, Wurtele, Eve, Wurtele, Eve   +5 more
core   +3 more sources

The Efficacy of Combination Therapy With SWTX Capsule and Paroxetine for Depression: A Randomized Controlled Trial

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Depression, a leading global cause of disease burden, often shows limited response and notable adverse reactions to existing antidepressants. Exploring combination therapies is therefore crucial to enhance therapeutic efficacy and improve safety.
Yanting Fan, Rula Sa, Ruiting Ma, Lijun Tong   +3 more
wiley   +1 more source

Structural Determinants for the Antidepressant Activity of St. John’s Wort (Hypericum perforatum): A Combined Theoretical and Experimental Study

Physchem
This study presents a systematic investigation of the dynamic and structural characteristics of St. John’s wort (Hypericum perforatum) in alcoholic solutions using experimental and theoretical techniques.
Afrodite Tryfon, George Petsis, Panagiota Siafarika, Evanthia Soubasi, Angelos G. Kalampounias   +4 more
doaj   +1 more source

THE PHYTOCHEMICAL ANALYSIS AND ANTIOXIDANT CAPACITY DETERMINATION OF FIVE HYPERICUM SPECIES

Studia Universitatis Babes-Bolyai Chemia, 2022
Medicinal plants are a valuable source of lead compounds and novel drugs. The Hypericum L. species traditionally treats skin wounds, sciatica, and depression.
Adaeze Adejoke ADEHUWA-OLABODE, Asmita SAUTREAU, Laurian VLASE, Ana-Maria VLASE, Dana MUNTEAN   +4 more
doaj   +1 more source

Neuroprotective activity of Hypericum perforatum and its major components [PDF]

, 2016
Hypericum perforatum is a perennial plant, with worldwide distribution, commonly known as St. Johns wort. It has been used for centuries in traditional medicine for the treatment of several disorders, such as minor burns, anxiety, and mild to moderate ...
Abbott, Agostinis, Akiyama, Albert, Alia, Altun, Ankarcrona, Ansari, Arredondo, Arredondo, Asanuma, Bains, Ball, Barnes, Behl, Behl, Behnke, Benedi, Boots, Borrelli, Breyer, Brunet, Butterfield, Butterweck, Butterweck, Chatterjee, Cheung, Cheung, Cheung, Chu, Cohen, Dajas, De Vry, Deane, Dinamarca, Dok-Go, Dona, Dostalek, El-Sherbiny, Emerit, Ferko, Filomeni, Filomeni, Garcia-Alloza, Gartner, Gaster, Goll, Greeson, Haleagrahara, Hammerness, Heim, Henderson, Heo, Hollman, Holtzman, Hostanska, Inal, Inestrosa, Jang, Kaltschmidt, Kamalakkannan, Karioti, Karminsky, Khan, Khan, Khawaja, Klusa, Knuppel, Kraus, Kubin, La Casa, Lin, Linde, Linde, Liu, Liu, Liu, Lu, Luo, Martarelli, Martinez-Poveda, Martinez-Poveda, McNaught, Miskovsky, Mohanasundari, Molina, Motallebnejad, Muller, Muralikrishnan, Myhrstad, Nahrstedt, Nahrstedt, Nakayama, Nieminen, Ossola, Patocka, Pfrunder, Pietta, Piscitelli, Rahimi, Ramos, Rattanajarasroj, Reichling, Rink, Rothley, Russo, Saddiqe, Sanchez-Reus, Sasaki, Schempp, Schmider, Schulz, Schwarz, Sestili, Sherer, Silva, Silva, Silva, Silva, Silva, Silva, Singer, Smith, Song, Suematsu, Suntar, Suzuki, Talesa, Wagner, Wang, Wang, Wang, Wurglics, Xu, Yang, Zeng, Zhang, Zhang, Zhao, Zheng, Zou, Zou   +141 more
core   +3 more sources