Results 41 to 50 of about 2,864 (178)
Variation of Bioactive Secondary Metabolites in Turra from Wild Populations of Turkey
Natural Product Communications, 2008 The present study was conducted to determine the variation in the content of hyperforin, hypericin and pseudohypericin in Hypericum triquetrifolium Turra growing wild in four locations of Turkey.
Necdet Çamaş +5 more
doaj +1 more source
POTENTIAL ANTICLASTOGENIC EFFECT OF HYPERFORIN [PDF]
Military Medical Science Letters, 2013 Summary Hyperforin is a prenylated phloroglucinol derivative which occurs in the plant Hypericum perforatum L. It has several medicinally important properties (antidepressant, anti-inflammatory, proapoptotic, antibacterial and antiangiogenic). To enable its medicinal use, it is necessary to investigate its potential genotoxic effect on human cell lines.
Petronela Imreová +4 more
openaire +1 more source
Quantifying Hyperforin in St. Johns Wort
, 2021 Hyperforin is a known compound naturally produced by St. Johns Wort plants and has been proven to help treat mild depression. The purpose of this project was to determine optimal growing conditions for this plant to maximize efficiency of hyperforin ...
Forster, Chase
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In vivo activity and pharmacokinetics of nemorosone on pancreatic cancer xenografts. [PDF]
PLoS ONE, 2013 Pancreatic cancer is one of the leading cancer-related causes of death in the western world with an urgent need for new treatment strategies. Recently, hyperforin and nemorosone have been described as promising anti-cancer lead compounds.
Robert J Wolf +4 more
doaj +1 more source
Arbeiten zur enantioselektiven Totalsynthese von Hyperforin [PDF]
, 2020 Diese Dissertation beschäftigt sich mit der enantioselektiven Synthese von Hyperforin, einem Naturstoff aus der Familie der polycyclischen polyprenylierten Acylphloroglucinen (PPAPs).
Frey, Sebastian
core +1 more source
Hyperforin Exhibits Antigenotoxic Activity on Human and Bacterial Cells
Molecules, 2017 Hyperforin (HF), a substance that accumulates in the leaves and flowers of Hypericum perforatum L. (St. John’s wort), consists of a phloroglucinol skeleton with lipophilic isoprene chains. HF exhibits several medicinal properties and is mainly used as an
Petronela Imreova +10 more
doaj +1 more source
PhyschemThis study presents a systematic investigation of the dynamic and structural characteristics of St. John’s wort (Hypericum perforatum) in alcoholic solutions using experimental and theoretical techniques.
Afrodite Tryfon +4 more
doaj +1 more source
Cells, 2019 Transient receptor potential canonical channel-6 (TRPC6) is one of the Ca2+-permeable non-selective cation channels. TRPC6 is mainly expressed in dentate granule cell (DGC), which is one of the most resistant neuronal populations to various harmful ...
Ji-Eun Kim +4 more
doaj +1 more source
THE PHYTOCHEMICAL ANALYSIS AND ANTIOXIDANT CAPACITY DETERMINATION OF FIVE HYPERICUM SPECIES
Studia Universitatis Babes-Bolyai Chemia, 2022 Medicinal plants are a valuable source of lead compounds and novel drugs. The Hypericum L. species traditionally treats skin wounds, sciatica, and depression.
Adaeze Adejoke ADEHUWA-OLABODE +4 more
doaj +1 more source
, 2013 Closely related chemical structures of hyperforin (left) and nemorosone (right), two polycyclic polyprenylated acylphloroglucinols.
Jens Werner (135131) +4 more
core +1 more source