Results 31 to 40 of about 1,559 (168)

Detection of virulence factors and antimicrobial susceptibility pattern of clinically significant Klebsiella pneumoniae isolates in a tertiary care hospital [PDF]

Microbes, Infection and Chemotherapy
Introduction: Klebsiella pneumoniae is associated with a variety of infections across all age groups, both in community and hospital settings. Many strains of K.
SMRITHI SURENDRANATH, Amritha Sabitha-Kurup, Reena John   +2 more
doaj   +2 more sources

Clinical and microbiological characteristics and occurrence of Klebsiella pneumoniae infection in Japan

International Journal of General Medicine, 2018
Mahoko Ikeda,1,2,* Miyuki Mizoguchi,1,* Yukie Oshida,3 Keita Tatsuno,1 Ryoichi Saito,4 Mitsuhiro Okazaki,5 Shu Okugawa,2 Kyoji Moriya1,2 1Department of Infection Control and Prevention, The University of Tokyo Hospital, Hongo, Bunkyo-ku, Tokyo, Japan ...
Ikeda M, Mizoguhi M, Oshida Y, Tatsuno K, Saito R, Okazaki M, Okugawa S, Moriya K   +7 more
doaj   +1 more source

Evaluation of ompK36 allele groups on clinical characteristics and virulence features of Klebsiella pneumoniae from bacteremia

Journal of Microbiology, Immunology and Infection, 2019
Background/purpose: This study investigated the implications of ompK36 allele groups on clinical and microbiological features of patients with Klebsiella pneumoniae bacteremia. Methods: A total of 80 K.
Fangling Du, Dan-dan Wei, La-Gen Wan, Xian-wei Cao, Wei Zhang, Yang Liu   +5 more
doaj   +2 more sources

Klebsiella pneumoniae sugar import suppresses hypermucoviscosity

Translation
Saroj Khadka, Laura A. Mike
doaj   +4 more sources

Two-Component Response Regulator OmpR Regulates Mucoviscosity through Energy Metabolism in Klebsiella pneumoniae

Microbiology Spectrum, 2023
Hypermucoviscosity is a hallmark of hypervirulent Klebsiella pneumoniae (hvKP). However, the molecular basis of its regulation is largely unknown. We hypothesize that hypermucoviscosity is modulated via two-component signal transduction systems (TCSs ...
Lijun Wang, Xueting Huang, Qian Jin, Jie Tang, Hua Zhang, Jing-Ren Zhang, Hui Wu   +6 more
doaj   +1 more source

Urine-mediated suppression of Klebsiella pneumoniae mucoidy is counteracted by spontaneous Wzc variants altering capsule chain length

mSphere, 2023
Klebsiella pneumoniae is a hospital-associated pathogen primarily causing urinary tract infections (UTIs), pneumonia, and septicemia. Two challenging lineages include the hypervirulent strains, causing invasive community-acquired infections, and the ...
Saroj Khadka, Brooke E. Ring, Ryan S. Walker, Lindsey R. Krzeminski, Drew A. Pariseau, Matthew Hathaway, Harry L. T. Mobley, Laura A. Mike   +7 more
doaj   +1 more source

Exploring the Antimicrobial Efficacy of Mesenchymal Stem Cell Secretome Against Klebsiella pneumoniae in Urinary Tract Infections. [PDF]

Clin Transl Sci
ABSTRACT Antimicrobial resistance (AMR) has become a global health crisis, with Klebsiella pneumoniae (K. pneumoniae) emerging as a major driver of AMR and a leading cause of urinary tract infections (UTIs). Mesenchymal stem cell (MSC)‐derived secretomes have gained attention for their antimicrobial properties.
Ali L, Sokhn ES, Khalil C, Saleh FA.
europepmc   +2 more sources

The small protein RmpD drives hypermucoviscosity in Klebsiella pneumoniae

mBio, 2020
ABSTRACT Klebsiella pneumoniae has a remarkable ability to cause a wide range of human diseases. It is divided into two broad classes: Classical strains that are a notable problem in healthcare settings due to multidrug resistance, and hypervirulent ( hv ) strains ...
Walker, Kimberly A., Treat, Logan P., Miller, Virginia L.   +2 more
openaire   +4 more sources

Functional Characterization of Plasmid-Borne rmpADC Homologues in Klebsiella pneumoniae

Microbiology Spectrum, 2023
Expression of the hypermucoviscosity (HMV) phenotype and capsular polysaccharide (CPS) biosynthesis in Klebsiella pneumoniae were reported to be encoded by genes located in the chromosomal rmp locus.
Xuemei Yang, Xiaoxuan Liu, Edward Wai-Chi Chan, Rong Zhang, Sheng Chen   +4 more
doaj   +1 more source

Microbiological and clinical characteristics of bacteraemia caused by the hypermucoviscosity phenotype ofKlebsiella pneumoniaein Korea [PDF]

Epidemiology and Infection, 2012
SUMMARYHypermucoviscous (HV) isolates ofKlebsiella pneumoniaehave been linked to virulence potential in experimental infections. We examined 33 isolates ofK. pneumoniaefrom patients with bacteraemia for the HV phenotype on agar culture, and determined their virulence potential by screening for capsular (K) serotype by polymerase chain reaction and the ...
S W, Jung, H J, Chae, Y J, Park, J K, Yu, S Y, Kim, H K, Lee, J H, Lee, J M, Kahng, S O, Lee, M K, Lee, J H, Lim, C H, Lee, S J, Chang, J Y, Ahn, J W, Lee, Y G, Park   +15 more
openaire   +3 more sources