Journal of Microbiology, Immunology and Infection, 2019 Background/purpose: This study investigated the implications of ompK36 allele groups on clinical and microbiological features of patients with Klebsiella pneumoniae bacteremia. Methods: A total of 80 K.
Fangling Du +5 more
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Detection and characterization of putative hypervirulent Klebsiella pneumoniae isolates in microbiological diagnostics [PDF]
Scientific Reports, 2023 Hypervirulent Klebsiella pneumoniae strains (hvKp) can cause invasive community-acquired infections in healthy patients of all ages. In this study, the prevalence of putative hvKp in a German tertiary center was investigated and hvKp were characterized ...
Bernd Neumann +12 more
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Distinct and shared impacts of virulence plasmids on the phenotype and transcriptome in convergent carbapenem-resistant and hypervirulent Klebsiella pneumoniae [PDF]
Microbiology SpectrumThe global rise of convergent carbapenem-resistant and hypervirulent Klebsiella pneumoniae (CR-hvKp) represents a major clinical challenge, yet the role of virulence plasmids (pVirs) in shaping bacterial physiology and pathogenicity remains incompletely ...
Mingju Hao +8 more
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Carbapenem-resistant Klebsiella pneumoniae from clinical infections: a multifactorial analysis of resistance, virulence, and biofilm potential [PDF]
Frontiers in Cellular and Infection MicrobiologyIntroductionKlebsiella pneumoniae has emerged as a major nosocomial pathogen, with hypermucoviscous and hypervirulent variants contributing to severe clinical outcomes. Understanding the interplay between antimicrobial resistance, virulence determinants,
Ramya Juliet, Ramesh Nachimuthu
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Detection of virulence factors and antimicrobial susceptibility pattern of clinically significant Klebsiella pneumoniae isolates in a tertiary care hospital [PDF]
Microbes, Infection and ChemotherapyIntroduction: Klebsiella pneumoniae is associated with a variety of infections across all age groups, both in community and hospital settings. Many strains of K.
SMRITHI SURENDRANATH +2 more
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International Journal of General Medicine, 2018 Mahoko Ikeda,1,2,* Miyuki Mizoguchi,1,* Yukie Oshida,3 Keita Tatsuno,1 Ryoichi Saito,4 Mitsuhiro Okazaki,5 Shu Okugawa,2 Kyoji Moriya1,2 1Department of Infection Control and Prevention, The University of Tokyo Hospital, Hongo, Bunkyo-ku, Tokyo, Japan ...
Ikeda M +7 more
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Microbiology Spectrum, 2023 Hypermucoviscosity is a hallmark of hypervirulent Klebsiella pneumoniae (hvKP). However, the molecular basis of its regulation is largely unknown. We hypothesize that hypermucoviscosity is modulated via two-component signal transduction systems (TCSs ...
Lijun Wang +6 more
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mSphere, 2023 Klebsiella pneumoniae is a hospital-associated pathogen primarily causing urinary tract infections (UTIs), pneumonia, and septicemia. Two challenging lineages include the hypervirulent strains, causing invasive community-acquired infections, and the ...
Saroj Khadka +7 more
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The small protein RmpD drives hypermucoviscosity in Klebsiella pneumoniae
mBio, 2020 ABSTRACT Klebsiella pneumoniae has a remarkable ability to cause a wide range of human diseases. It is divided into two broad classes: Classical strains that are a notable problem in healthcare settings due to multidrug resistance, and hypervirulent ( hv ) strains ...
Walker, Kimberly A. +2 more
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Functional Characterization of Plasmid-Borne rmpADC Homologues in Klebsiella pneumoniae
Microbiology Spectrum, 2023 Expression of the hypermucoviscosity (HMV) phenotype and capsular polysaccharide (CPS) biosynthesis in Klebsiella pneumoniae were reported to be encoded by genes located in the chromosomal rmp locus.
Xuemei Yang +4 more
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