Results 111 to 120 of about 4,451 (204)

Genomic analyses identify nosocomial transmission of ST23 carbapenem-resistant hypervirulent Klebsiella pneumoniae mediated by a conjugative IncFIIK2 NDM-1 plasmid

Virulence
The World Health Organization has identified ST23 carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) as a critical public health threat.
Tao Chen, Xueting Wang, Luying Xiong, Yan Geng, Hui Ding, Yunbo Chen, Ping Shen, Yonghong Xiao   +7 more
doaj   +1 more source

Emergence of carbapenem-resistant hypervirulent Klebsiella pneumoniae [PDF]

The Lancet Infectious Diseases, 2018
Hong, Yao, Shangshang, Qin, Sheng, Chen, Jianzhong, Shen, Xiang-Dang, Du   +4 more
  +9 more sources

Insertion sequences accelerate genomic convergence of multidrug resistance and hypervirulence in Klebsiella pneumoniae via capsular phase variation

Background The convergence of resistance and hypervirulence in Klebsiella pneumoniae represents a significant public health threat, driven by the horizontal transfer of plasmids. Understanding factors affecting plasmid transfer efficiency is essential to
Gang Zhang, Jie Feng, Da-Wei Wei, Jiangqing Huang, Xueru Tian, Chao Wang, Yuqin Song, Yi Li, Linhuan Wu, Qi Chen   +9 more
core   +1 more source

Hypervirulent knockout [PDF]

Genome Biology, 2001
openaire   +1 more source

Genomic evolution and dissemination of non-conjugative virulence plasmid of ST65 carbapenem-resistant and hypervirulent Klebsiella pneumoniae strains in a Chinese hospital

Frontiers in Cellular and Infection Microbiology
BackgroundThe global rise in infections caused by hypervirulent and carbapenem-resistant K. pneumoniae (CR-hvKp) represents a growing public health threat.
Dongxing Tian, Dongxing Tian, Dongxing Tian, Mingqi Zhao, Lihua Liu, Shuhua Lu, Haixin Dong   +6 more
doaj   +1 more source

The surface protein HvgA mediates group B streptococcus hypervirulence and meningeal tropism in neonates

, 2010
Streptococcus agalactiae (group B streptococcus; GBS) is a normal constituent of the intestinal microflora and the major cause of human neonatal meningitis. A single clone, GBS ST-17, is strongly associated with a deadly form of the infection called late-
Trieu-Cuot, Patrick, Tazi, Asmaa, Patrick Trieu-Cuot, Bouaboud, Abdelouhab, Bellais, Samuel, Dramsi, Shaynoor, Michel-Yves Mistou, Claire Poyart, Lecuit, Marc, Tardieux, Isabelle, Poyart, Claire, Nicolas Dmytruk, Mechler, Charlotte, Olivier Disson, Samuel Bellais, Dmytruk, Nicolas, Mistou, Michel-Yves, Marc Lecuit, Asmaa Tazi, Shaynoor Dramsi, Huot Khun, Isabelle Tardieux, Disson, Olivier, Abdelouhab Bouaboud, Charlotte Mechler, Khun, Huot   +25 more
core   +1 more source

Draft genome sequence of Klebsiella pneumoniae KLEB-33: a convergent biofilm hyperforming multiresistant strain belonging to the emerging ST16 lineage harboring multiple hypervirulence genes

The emergence of convergent Klebsiella pneumoniae strains showing multiresistance, characteristic of nosocomial pathotypes and hypervirulent traits typical of community-acquired isolates, makes them important models for studying K.
Silva-Bea, Sergio, Rey, Sonia, Fernández, Javier, García-Meniño, Isidro, Romero, Manuel, Mora, Azucena, Hammerl, Jens A., Otero, Ana   +7 more
core   +1 more source

Evolution of hypervirulence in Klebsiella [PDF]

Nature Reviews Microbiology, 2015
openaire   +1 more source

Acquisition of a stable and transferable plasmid coharbouring hypervirulence and MDR genes with low fitness cost: Accelerating the dissemination of ST11-KL64 CR-HvKP

Objectives: This study aimed to delineate the ability of a plasmid, pS130–4, which harboured both hypervirulence and multidrug resistance genes, to disseminate within Klebsiella pneumoniae, as well as its potential formation mechanism.
Binghui Huo, DanDan Wei, Ping Li, ChunPing Wei, Qun Ren, QiSen Huang, Jiehui Qiu, Shanshan Huang, Yang Liu, LinPing Fan   +9 more
core   +1 more source

The oral cavity as a reservoir for resistance- and hypervirulence-associated genes of Klebsiella pneumoniae in hospitalized patients

IntroductionThis study investigated the epidemiology and distribution of carbapenem resistance and virulence genes in Klebsiella pneumoniae strains isolated from the oral cavity of hospitalized patients, highlighting their role as reservoirs in non ...
Djellali Belhadi, Touati, Abdelaziz, Ehricht, Ralf, Mostefaoui, Raouya, Fatma Zohra Zaidi, Karima Zenati, Elke Müller, Zaidi, Fatma Zohra, Stefan Monecke, Amira A. Moawad, M\ufcller, Elke, Diezel, Celia, Brandt, Christian, Mohamed Belmahdi, Braun, Sascha D., Zenati, Karima, Moawad, Amira A., Raouya Mostefaoui, Abdelaziz Touati, Ralf Ehricht, Belhadi, Djellali, Monecke, Stefan, Sascha D. Braun, Belmahdi, Mohamed, Christian Brandt, Celia Diezel   +25 more
core   +1 more source