Results 91 to 100 of about 4,765 (201)

Interplay Between Virulence Genes, Antimicrobial Resistance Profiles, and Biofilm Formation in Klebsiella pneumoniae Causing Urinary Tract Infections in North Lebanon

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
– Figure design (single panel) Central icon: K. pneumoniae cell Left panel – Virulence genes (icons): Adhesion: fimH, mrkD → strong biofilm Capsule/regulation: magA, rmpA Siderophores: entB, iucA → iron uptake Right panel – Outcomes: Biofilm strength (weak → strong gradient) Antibiotic resistance (ESBL, MDR) Bottom split: Hospital‐acquired → strong ...
Mazen Zaylaa, Rayan Farha, Jana Taleb, Amal Saad, Omar El Gharbawy, Ricardo Sarraf, Ibtihal Kassam, Chadi Hamdach, Nisrine Bissar   +8 more
wiley   +1 more source

Metastatic infection of hypervirulent Klebsiella pneumoniae

IDCases
Hypervirulent Klebsiella pneumoniae(hvKp) has a unique ability to cause organ or life-threatening tissue invasive infection in multiple sites. This case highlights that classical hvKp resulted in multiple abscesses in every body site, especially in the necrotizing fasciitis and osteomyelitis.
Biying Zhang, Chao Liu, Yunfei Tang, Thomas A. Russo, Ming Lu   +4 more
openaire   +3 more sources

Convergence of Hypervirulence and Multidrug-Resistance in Burkholderia cepacia Complex Isolates from Patients with COVID-19 [PDF]

Mengjiao Du,1,2,* Cheng Chi,1,* LuYing Xiong,2 Jincheng Rong,1 Maoli Yi,1 Qi Zhao,1 Xiaohui Chi1 1Department of Medical Laboratory, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, People’s Republic of China ...
Xiong L, Zhao Q, Chi C, Yi M, Chi X, Rong J, Du M   +6 more
core  

Pathogenic Mechanisms of V. vulnificus and Its Role in the Development of Sepsis

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Sorafenib attenuates urethral scar formation by inhibiting β‐catenin signaling in fibroblasts, which downregulates the SLC7A11/GPX4 antioxidant axis and triggers ferroptosis. This β‐catenin–ferroptosis coupling effectively suppresses fibrogenesis, highlighting sorafenib as a promising drug‐repurposing candidate for urethral stricture.
Zhongying Yu, Xianzhong Zhu, Shijie Tang, Shubo Yang, Jinyu Li, Lianzhong Luo, Yan Tan, Jun Yin   +7 more
wiley   +1 more source

Genetic Switch to Hypervirulence Reduces Colonization Phenotypes of the Globally Disseminated Group A Streptococcus M1T1 Clone

, 2020
Background. The recent resurgence of invasive group A streptococcal disease has been paralleled by the emergence of the M1T1 clone. Recently, invasive disease initiation has been linked to mutations in the covR/S 2-component regulator.
Streptococcus, Jid, • Clone, A Group
core  

Facing Antimicrobial Resistance and Virulence in Streptococcus agalactiae During Late Pregnancy: Evaluation of Lactobacilli as a Supportive Approach

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Integrated phenotypic, genotypic, and functional characterization of clinical Streptococcus agalactiae (Group B streptococcus, GBS) isolates from maternal carriage. Combination of selected Lactobacillus species effectively antagonize S. agalactiae by limiting bacterial growth, preserving epithelial cell viability, and reducing pathogen adhesion ...
Astri D. Tagueha, Giulia Radocchia, Daniela Scribano, Matteo Lo Scalzo, Giacinto Panella, Serena Schippa, Giovanni Gherardi, Roberta Creti, Ilaria Marani, Giovanna Alfarone, Monica Imperi, Massimiliano Marazzato, Lucia Nencioni, Paola Checconi, Dolores Limongi, Anna Teresa Palamara, Cecilia Ambrosi   +16 more
wiley   +1 more source

Emergence and characteristics of hypervirulent Acinetobacter baumannii

BMC Infectious Diseases
OBJECTIVE: This study aimed to characterize hypervirulent Acinetobacter baumannii (Hv-AB) strains and elucidate their clinical and microbiological profiles in a hospital setting. METHODS: We conducted a retrospective analysis of 49 A. baumannii strains isolated from a Chinese hospital between July 2019 and June 2020. Strains were classified as Hv-AB or
Shi, Jianglong, Liu, Ren, Qiu, Jiehui, Wei, Chunping, Pan, Dejin, He, Zhiyong, Li, Yang, Xiang, Tianxin, Cheng, Na   +8 more
openaire   +2 more sources

Mitochondria and the regulation of hypervirulence in the fatal fungal outbreak on Vancouver Island

, 2010
In our recent paper, we demonstrated that the hypervirulence exhibited by a lineage of the fatal fungal pathogen Cryptococcus gattii is associated with its mitochondrial gene expression and an unusual mitochondrial morphology.
Hansong Ma, Robin C. May, Ma, Hansong; id_orcid, May, Robin C.; id_orcid   +3 more
core   +1 more source

Mycovirus induced hypervirulence of Leptosphaeria biglobosa enhances systemic acquired resistance to Leptosphaeria maculans in Brassica napus [PDF]

, 2019
Phoma stem canker (blackleg) is one of the most important diseases of winter oilseed rape (Brassica napus) world-wide and is caused by a complex that comprises at least two species: Leptosphaeria maculans and Leptosphaeria biglobosa. Screening a panel of
Kotta-Loizou, Ioly, Coutts, Robert, Fitt, Bruce, Shah, Unnati   +3 more
core   +1 more source

Table_1_Epidemiological characteristics and molecular evolution mechanisms of carbapenem-resistant hypervirulent Klebsiella pneumoniae.DOCX

, 2022
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP), a type of Klebsiella pneumoniae (KP) that exhibits hypervirulence and carbapenem resistance phenotypes, can cause severe infections, both hospital- and community-acquired infections.
Wen-Qi Zheng (13772863), Xi-Shan Cao (13772857), Jian-Xun Wen (13772860), Yu-Ling Han (13772851), Wen Zhao (302324), Jun-Rui Wang (2259076), Zhi-De Hu (617056), Xu-Hui Wen (13772854)   +7 more
core   +1 more source