Results 91 to 100 of about 5,988 (207)

Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives. [PDF]

, 2006
p-Hydroxybenzoic acid derivatives (p-HBADs) are glycoconjugates secreted by all Mycobacterium tuberculosis isolates whose contribution to pathogenicity remains to be determined. The pathogenicity of three transposon mutants of M.
Aaron Rae, Avraham Liav, Brennan, Brian D. Robertson, Brigitte Gicquel, Briken, Charlab, Constant, Douglas B. Lowrie, Douglas B. Young, Flynn, Flynn, Frédéric Boudou, Gatfield, Germain Puzo, Gustavo Stadthagen, Hisert, Hunter, Iveta Bottova, Jackson, Jackson, Jérôme Nigou, Kaufmann, Launois, Mamadou Daffé, Manca, Mary Jackson, Michel Huerre, Nathalie Barilone, Nigou, Orme, Patricia Charles, Patricia Constant, Pearline Benjamin, Prod'hom, Puzo, Pérez, Pérez, Quesniaux, Rao, Reed, Ricardo E. Tascon, Roger S. Buxton, Rousseau, Ruth Griffin, Silva, Stadthagen, Stephen Coade, Tailleux, Thérèse Brando, Tsenova, Vachula, Vachula   +52 more
core   +1 more source

Metastatic infection of hypervirulent Klebsiella pneumoniae

IDCases
Hypervirulent Klebsiella pneumoniae(hvKp) has a unique ability to cause organ or life-threatening tissue invasive infection in multiple sites. This case highlights that classical hvKp resulted in multiple abscesses in every body site, especially in the necrotizing fasciitis and osteomyelitis.
Biying Zhang, Chao Liu, Yunfei Tang, Thomas A. Russo, Ming Lu   +4 more
openaire   +3 more sources

Whole-genome analysis of Exserohilum rostratum from an outbreak of fungal meningitis and other infections [PDF]

, 2014
Exserohilum rostratum was the cause of most cases of fungal meningitis and other infections associated with the injection of contaminated methylprednisolone acetate produced by the New England Compounding Center (NECC).
Brandt, Mary E., Changayil, Shankar, Engelthaler, David M., Frace, Michael A., Gade, Lalitha, Gillece, John D., Hilsabeck, Remy, Hurst, Steven, Keim, Paul, Litvintseva, Anastasia P., Lockhart, Shawn R., MacCannell, Duncan R., Roe, Chandler, Schupp, James M., Smith, David, Weil, M. Ryan   +15 more
core   +1 more source

TreC: A Critical Mediator of lysoPC‐Induced Hypervirulence in Streptococcus suis

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Streptococcus suis, a major zoonotic pathogen, employs diverse strategies to enhance virulence, yet the role of host‐derived metabolites in its pathogenicity remains underexplored. Here, we reveal a novel mechanism by which S. suis utilizes lysophosphatidylcholine (lysoPC), a host lipid signaling molecule, to enhance its virulence through treC ...
Xuefeng Cao, Jiajia Zheng, Song Xue, Qinyu Wei, Marc M. S. M. Wösten, Lianci Peng, Zhiwei Li, Rendong Fang, Anusak Kerdsin   +8 more
wiley   +1 more source

Hypervirulent Klebsiella pneumoniae – clinical and molecular perspectives [PDF]

Journal of Internal Medicine, 2019
AbstractHypervirulent Klebsiella pneumoniae (hvKp) has emerged as a concerning global pathogen. hvKp is more virulent than classical K. pneumoniae (cKp) and capable of causing community‐acquired infections, often in healthy individuals. hvKp is carried in the gastrointestinal tract, which contributes to its spread in the community and healthcare ...
J. E. Choby, J. Howard‐Anderson, D. S. Weiss   +2 more
openaire   +2 more sources

The Occurence of Colistin-Resistant Hypervirulent Klebsiellapneumoniae in China

Frontiers in Microbiology, 2018
Hypervirulent Klebsiella pneumoniae strains are usually susceptible to many antimicrobial agents including colistin. Here we report the isolation and characterization of several colistin-resistant hypervirulent K. pneumoniae clinical strains.
Yang Lu, Yang Lu, Yang Lu, Yu Feng, Yu Feng, Yu Feng, Alan McNally, Zhiyong Zong, Zhiyong Zong, Zhiyong Zong   +9 more
doaj   +1 more source

Dual glycosylation of wall teichoic acid modulates the O‐antigen pattern and virulence in serovar 4b Listeria monocytogenes

mLife, Volume 4, Issue 6, Page 638-650, December 2025.
Abstract Among the 14 serovars of Listeria monocytogenes (Lm), serovar 4b strains are the most predominant isolates linked to human listeriosis outbreaks‐a phenotype associated with their unique wall teichoic acid (WTA) decorated with galactose (Gal) and glucose (Glu).
Hao Yao, Yuting Wang, Ruochen Wang, Zhengnan Dong, Zhenhua Wu, Luyong Wang, Yuelan Yin, Xin'an Jiao   +7 more
wiley   +1 more source

Acquisition of the Sda1-encoding bacteriophage does not enhance virulence of the serotype M1 Streptococcus pyogenes strain SF370 [PDF]

, 2013
The resurgence of invasive disease caused by Streptococcus pyogenes (group A Streptococcus [GAS]) in the past 30 years has paralleled the emergence and global dissemination of the highly virulent M1T1 clone.
Ashbaugh CD, Aziz RK, Banks DJ, Beres SB, Canchaya C, Chiarot E, Cleary PP, Cole JN, Collin M, Cone LA, Kansal RG, Kazmi SU, Maamary PG, Maamary PG, Miyoshi-Akiyama T, Nauseef WM, Nizet V, Olsen RJ, Otto TD, Sullivan MJ, Sun H, Walker MJ   +21 more
core   +1 more source

2024 Bangladesh Floodwaters Harbour Regional Hotspots of Pathogens and Antimicrobial Resistance

Environmental Microbiology Reports, Volume 17, Issue 6, December 2025.
Metagenomic analysis of Bangladesh floodwaters reveals diverse pathogens (Klebsiella pneumoniae, Pseudomonas aeruginosa), antimicrobial resistance genes (blaOXA, ermB), and mobilizable plasmids (IncP1, Col440I), highlighting floodwaters as reservoirs for microbial hazards and AMR dissemination, with region‐specific risks demanding targeted public ...
Tanzim Rahman, Nure Sharaf Nower Samia, Shovan Basak Moon, Md. Shafiqul Islam, Zahid Hayat Mahmud, Md. Shahidul Kabir, Muhammad Manjurul Karim, Mustafizur Rahman, Mohammad Jubair   +8 more
wiley   +1 more source

Pathogenic Potential of Invasive Mucosa‐Associated Klebsiella pneumoniae Isolates in Ulcerative Colitis: Characterization of Virulence Factors and Inflammatory Response

Immunity, Inflammation and Disease, Volume 13, Issue 10, October 2025.
This study was conducted in 83 patients with ulcerative colitis (UC). Klebsiella pneumoniae isolates showed a higher prevalence of virulence genes (fimH, hcp, fyuA, irp1) compared to non‐UC controls. UC isolates exhibited increased adhesion (29% vs. 8%) and invasion (16% vs.
Ensieh Olamafar, Abbas Yadegar, Shabnam Shahrokh, Maryam Tajabadi Ebrahimi, Hamidreza Houri   +4 more
wiley   +1 more source