Results 101 to 110 of about 4,451 (204)

Predomination of hypervirulent ST283 and genetic diversity of levofloxacin resistance in multidrug-resistant, hypervirulent Streptococcus agalactiae in Thailand

Journal of Medical Microbiology
Introduction. Group B Streptococcus (GBS) is a multi-host pathogen causing pneumonia and meningitis in humans as well as streptococcal diseases in tilapia and mastitis in cattle. Thailand has experienced a significant increase in GBS infections that greatly impact health and economics. Gap statement.
Wajeeorn Ouancharee, Anusak Kerdsin, Hien Van Doan, Chanagun Chitmanat, Kiatichai Faksri, Aroonlug Lulitanond, Aroonwadee Chanawong, Nicha Charoensri   +7 more
openaire   +2 more sources

Mitochondria and the regulation of hypervirulence in the fatal fungal outbreak on Vancouver Island

, 2010
In our recent paper, we demonstrated that the hypervirulence exhibited by a lineage of the fatal fungal pathogen Cryptococcus gattii is associated with its mitochondrial gene expression and an unusual mitochondrial morphology.
Hansong Ma, Robin C. May, Ma, Hansong; id_orcid, May, Robin C.; id_orcid   +3 more
core   +1 more source

The anti-sigma factor TcdC modulates hypervirulence in an epidemic BI/NAP1/027 clinical isolate of Clostridium difficile [PDF]

, 2011
Nosocomial infections are increasingly being recognised as a major patient safety issue. The modern hospital environment and associated health care practices have provided a niche for the rapid evolution of microbial pathogens that are well adapted to ...
Mackin, Kate, Lyras, D., Revathi Govind, Carter, Glen P., Spencer, J., Glen P Carter, Julian I Rood, Mackin, Kate E., Antunes, Ana, Pauline M. Howarth, Kotsanas, D, Buckley, Anthony, Howarth, PM, Ana Antunes, Buckley, AM, Govind, Revathi, Kate E. Mackin, Howarth, P.M., Grant A Jenkin, Despina Kotsanas, Lyras, D, Rood, Julian I., Govind, R, Douce, Gillian R., Kotsanas, Despina, Kate E Mackin, Mackin, KE, Spencer, Janice, Rood, J.I., Rood, Julian, Carter, G.P., Gillian R Douce, Carter, GP, Jenkin, G.A., Carter, Glen, Buckley, A.M., Bruno Dupuy, Jenkin, Grant A., Grant A. Jenkin, Janice Spencer, Dena Lyras, Julian I. Rood, Jenkin, GA, Govind, R., Lyras, Dena, Koehler, T.M., Pauline M Howarth, Anthony M. Buckley, Dupuy, B., Rood, JI, Mackin, K.E., Spencer, J, Jenkin, Grant, Douce, G.R., Kotsanas, D., Anthony M Buckley, Glen P. Carter, Gillian R. Douce, Buckley, Anthony M., Howarth, Pauline, Antunes, A., Douce, GR, Antunes, A, Howarth, Pauline M., Dupuy, B, Douce, Gillian, Dupuy, Bruno   +66 more
core   +1 more source

Genetic Switch to Hypervirulence Reduces Colonization Phenotypes of the Globally Disseminated Group A Streptococcus M1T1 Clone

, 2020
Background. The recent resurgence of invasive group A streptococcal disease has been paralleled by the emergence of the M1T1 clone. Recently, invasive disease initiation has been linked to mutations in the covR/S 2-component regulator.
Streptococcus, Jid, • Clone, A Group
core  

Evolved Aztreonam Resistance Is Multifactorial and Can Produce Hypervirulence in Pseudomonas aeruginosa

, 2017
While much attention has been focused on acquired antibiotic resistance genes, chromosomal mutations may be most important in chronic infections where isolated, persistently infecting lineages experience repeated antibiotic exposure.
Rachel A. Harwood, Anina Ratjen, Sumedha Ravishankar, Pradeep K. Singh, Kathryn McLean, Adam Waalkes, Kelsi Penewit, Amir Rezayat, Gilbert E. Bautista, Patrick R. Secor, Joe J. Harrison, Stephen J. Salipante, Jayanthi Garudathri, Peter Jorth   +13 more
core   +2 more sources

A Step Forward in Hypervirulent Klebsiella pneumoniae Diagnostics

Emerging Infectious Diseases
Hypervirulent Klebsiella pneumoniae (hvKp) can cause life-threatening infections in healthy community members. HvKp infections often involve multiple sites, some of which are unusual for classical K. pneumoniae (cKp) infections, such as the central nervous system, eyes, and fascia.
Thomas A. Russo, Francois Lebreton, Patrick T. McGann   +2 more
openaire   +3 more sources

Multicenter Surveillance of Klebsiella pneumoniae: Resistance Shifts, CRKP Prevalence and Hypervirulent Evolution Trajectories in Hebei, China (2019-2023)

Infection and Drug Resistance
Kaiyue Xu,1,2,* Shiying Fan,3,* Ziye Liu,4,* Cuixin Qiang,1,5,6 Jiansheng Wang,7 Pu Qin,1,5,6 Ziyuan Mao,4 Ya Wu,2 Zhirong Li,1,5,6 Jianhong Zhao1,5,6 1Hebei Provincial Center for Clinical Laboratories, The Second Hospital of ...
Xu K, Fan S, Liu Z, Qiang C, Wang J, Qin P, Mao Z, Wu Y, Li Z, Zhao J   +9 more
doaj  

Prevalence and features of hypervirulent Klebsiella pneumoniae in respiratory specimens at a US hospital system

Infection and Immunity
Hypervirulent Klebsiella pneumoniae (hvKp) strains are considered to be relatively rare in the United States, but cases are increasingly reported. We prospectively and serially collected K. pneumoniae clinical isolates identified in respiratory specimens
Christi L. McElheny, Alina Iovleva, Nathalie Chen, Dominic Woods, Akansha Pradhan, Jonah L. Sonnabend, Aidan R. Matunis, Nathan J. Raabe, Janet S. Lee, Giraldina Trevejo-Nuñez, Daria Van Tyne, Yohei Doi   +11 more
doaj   +1 more source

The hypervirulent Type-1/Type-17 phenotype of Cryptococcus neoformans clinical isolates is specific to A/J mice

Infection and Immunity
Cryptococcus neoformans is a fungal pathogen that causes cryptococcal meningitis in immunocompromised individuals. Both host- and pathogen-specific factors are known to affect patient outcome, and recent studies showed that strain-specific differences in
Minna Ding, Katrina M. Jackson, Madeline Harris-Gordon, Thamotharampillai Dileepan, David B. Meya, Kirsten Nielsen   +5 more
doaj   +1 more source

Neutrophil function in hypervirulent Klebsiella pneumoniae infection [PDF]

The Lancet Microbe, 2022
Guan Yang, Qi Xu, Sheng Chen
openaire   +3 more sources