Results 81 to 90 of about 4,765 (201)

Eco‐Geography Reverses Dominant AMR Reservoirs in Klebsiella pneumoniae: Integron‐Rich Mobilomes and Cross‐Niche Connectivity

Advanced Science, Volume 13, Issue 42, 28 July 2026.
Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin, Biao Tang, Hao Xu, Jiajie Qian, Feifan Shi, Junhui Zhao, Xiaorui Mao, Xiaohe Hu, Ruishan Liu, Wenhong Liu, Xiawei Jiang, Beiwen Zheng, Guoping Zhao   +12 more
wiley   +1 more source

Occurrence of colistin-resistant hypervirulent Klebsiella variicola [PDF]

Journal of Antimicrobial Chemotherapy, 2018
A colistin-resistant mucoid Klebsiella strain was recovered from the blood of a patient in China. Hypervirulence has been reported in Klebsiella pneumoniae, but not in other Klebsiella spp. The strain was suspected to be hypervirulent and was therefore characterized.The strain was subjected to genome sequencing using both the short-read Illumina HiSeq ...
Yang Lu, Yu Feng, Alan McNally, Zhiyong Zong   +3 more
openaire   +2 more sources

Genomic dynamics of high-risk carbapenem-resistant Klebsiella pneumoniae clones carrying hypervirulence determinants in Egyptian clinical settings [PDF]

Background Ongoing studies have revealed the global prevalence of severe infections caused by the hypervirulent strains of Klebsiella pneumoniae (K. pneumoniae).
Shahira A. ElBanna, Cobo Díaz, José Francisco, Shawky, Sherine M., Shata, Ahmed H., Mohamed Elhadidy, Nehal Adel Abdelsalam, Atteya, Reham, Ahmed H. Shata, Elhadidy, Mohamed, José F. Cobo-Díaz, Mouftah, Shaimaa F, Sherine M. Shawky, ElBanna, Shahira A., Abdelsalam, Nehal Adel, Reham Atteya, Shaimaa F. Mouftah   +15 more
core   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Evaluation of the pathogenicity and virulence of three strains of Salmonella organisms in calves and pigs [PDF]

, 2010
Objective—To assess in pigs the pathogenicity and virulence of 3 strains of Salmonella spp capable of causing atypical salmonellosis in cattle. Animals—36 Holstein calves and 72 pigs experimentally infected with Salmonella spp Procedures—Representative ...
Brewer, Matt, Nalee Xiong, Kimber, Michael, Michael J. Kimber, Xiong, Nalee, Tim A. Day, Steve A. Carlson, Matt T. Brewer, Day, Tim, Alison E. Barnhill, Carlson, Steve, Barnhill, Alison   +11 more
core   +1 more source

Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic

, 2017
Reference strains are a key component of laboratory research, providing a common background allowing for comparisons across a community of researchers.
Tanurdzic, Milos, Arras, Samantha D. M., Carpenter, Alex C., Espinosa, Monica I., Fraser, James A., Ormerod, Kate L., Blundell, Ross D., Stowasser, Samantha R., Erpf, Paige E., Schulz, Benjamin L.   +9 more
core   +2 more sources

Local Thermal Adaptation in an Insect‐Transmitted Plant Pathogen: The Role of Virulence Trade‐Offs

Evolutionary Applications, Volume 19, Issue 7, July 2026.
ABSTRACT Little is known about local adaptation to temperature in bacterial pathogen populations in nature. For plant‐pathogenic bacteria, local thermal adaptation may influence the evolution of virulence, which has strong implications for disease management and mitigation.
Monica A. Donegan, Josephine Nuño, Ranlin Liu, Leonardo De La Fuente, Rodrigo P. P. Almeida   +4 more
wiley   +1 more source

Carbapenem Resistance and Hypervirulence in Pediatric Klebsiella pneumoniae Sepsis

Background: Klebsiella pneumoniae is a major etiological agent of pediatric sepsis.
Eman HM. Salem, Mohamed Ahmed Noureldin, Karim Abdelfattah Montasser, Dina Mohammed Abdel-Hady, Maysaa El Sayed Zaki   +4 more
core   +1 more source

Fusarium sacchari 14‐3‐3 Protein FsBmh1 Sequesters a Novel Elicitor FsEcm33 to Evade Host Immunity

Molecular Plant Pathology, Volume 27, Issue 7, July 2026.
When the elicitor FsEcm33 is sprayed onto Nicotiana benthamiana leaves, it enters the apoplast, triggering PAMP‐triggered immunity (PTI) that depends on NbRE02, NbBAK1, and NbSOBIR1. However, upon Fusarium sacchari infection, FsBmh1 binds FsEcm33 to prevent its localization on the cell surface, escaping PTI to allow colonization.
Yuejia Chen, Yuming Lin, Lixian Zhao, Gengzhong Cheng, Liuting Huang, Yueying Zhao, Zhien Wei, Yuanzhi Mao, Xiaoxi Feng, Xipu He, Baoshan Chen, Jisen Zhang, Ziting Yao, Chengwu Zou   +13 more
wiley   +1 more source

Mycoviruses as Biocontrol Agents: Potential Applications for Managing Pests and Diseases of Oilseed Rape (Brassica napus)

Physiologia Plantarum, Volume 178, Issue 4, July/August 2026.
ABSTRACT Oilseed rape (Brassica napus) production faces a wide range of biotic threats. Pests typically pose a greater threat than diseases to oilseed rape, yet both vary considerably across the major cultivating regions. Management strategies often rely heavily on the use of chemical pesticides which may have harmful effects on the environment, thus ...
Harry J. Aston, Robert H. A. Coutts, Yong‐Ju Huang, Ioly Kotta‐Loizou   +3 more
wiley   +1 more source