Results 71 to 80 of about 3,484 (175)

Clinical Epidemiological Analysis of the Genotypic Spectrum and Mortality Risk in Carbapenem‐Resistant Klebsiella pneumoniae (CRKP) Infections

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Background Carbapenem‐resistant Klebsiella pneumoniae (CRKP) has become a global public health threat, with significantly increased morbidity and mortality among high‐risk inpatients. High‐risk genotypes of CRKP, primarily including K. pneumoniae carbapenemase (KPC), oxacillinase‐48–like (OXA‐48–like), New Delhi metallo‐β‐lactamase (NDM), imipenemase ...
Qiongfang Zhang, Ze Fang, Bo Fang, Hailing Zeng, Jiaojiao Xu, Muhammad Abu Bakr Shabbir   +5 more
wiley   +1 more source

Trends and Disparities in Clostridioides difficile Infection Mortality in the United States From 1999 to 2020: A Nationwide Perspective

Gastroenterology Research and Practice, Volume 2026, Issue 1, 2026.
Background Clostridioides difficile infection (CDI) is one of the most prevalent infections in the United States, with rising mortality and disease severity in the early 2000s, followed by a steady decline after 2010. This study analyzes national trends in CDI mortality across different demographic and regional groups from 1999 to 2020. Methods We used
Mohamed H. Eldesouki, Abdul-rahman Abusalim, Mohammad Kloub, Muhammed Umer, Mohamed Ahmed Ali, Ahmed Yasser Shaban, Ahmed Salem, Anas Almoghrabi, Jihad Slim, Yatinder Bains, Theodore Dacosta, Shweta Negi   +11 more
wiley   +1 more source

Defects in the Ferroxidase That Participates in the Reductive Iron Assimilation System Results in Hypervirulence in Botrytis Cinerea

mBio, 2020
The plant pathogen Botrytis cinerea is responsible for gray-mold disease, which infects a wide variety of species. The outcome of this host-pathogen interaction, a result of the interplay between plant defense and fungal virulence pathways, can be ...
Esteban Vasquez-Montaño, Gustavo Hoppe, Andrea Vega, Consuelo Olivares-Yañez, Paulo Canessa   +4 more
doaj   +1 more source

Nosocomial Klebsiella pneumoniae infection in a cardiac surgery hospital: clinical and microbiological features

Инфекция и иммунитет
Klebsiella pneumoniae dominates among the pathogens that cause healthcare-associated infections and closely associated with high mortality of patients undergoing heart surgery. K. pneumoniae spp.
M. V. Kuznetsova, V. S. Mihailovskaya, L. G. Kudryavtseva, V. I. Sergevnin   +3 more
doaj   +1 more source

Analysis of virulence profiles in clinical isolates of Klebsiella pneumoniae from renal abscesses: clinical significance of hypervirulent isolates

Frontiers in Cellular and Infection Microbiology
IntroductionKlebsiella pneumoniae can cause a wide range of infections. Hypervirulent K. pneumoniae (hvKp), particularly associated with the K1 and K2 capsular types, is an increasingly significant microorganism with the potential to cause invasive ...
Jaehyeon Lee, Jaehyeon Lee, Jeong-Hwan Hwang, Jeong-Hwan Hwang, Ji Hyun Yeom, Ji Hyun Yeom, Sik Lee, Sik Lee, Joo-Hee Hwang, Joo-Hee Hwang   +9 more
doaj   +1 more source

Transcriptomic Analysis Reveals Molecular Mechanisms Underpinning Mycovirus-Mediated Hypervirulence in Beauveria bassiana Infecting Tenebrio molitor

Journal of Fungi
Mycoviral infection can either be asymptomatic or have marked effects on fungal hosts, influencing them either positively or negatively. To fully understand the effects of mycovirus infection on the fungal host, transcriptomic profiling of four Beauveria
Charalampos Filippou, Robert H. A. Coutts, Ioly Kotta-Loizou, Sam El-Kamand, Alexie Papanicolaou   +4 more
doaj   +1 more source

Predomination of hypervirulent ST283 and genetic diversity of levofloxacin resistance in multidrug-resistant, hypervirulent Streptococcus agalactiae in Thailand

Journal of Medical Microbiology
Introduction. Group B Streptococcus (GBS) is a multi-host pathogen causing pneumonia and meningitis in humans as well as streptococcal diseases in tilapia and mastitis in cattle. Thailand has experienced a significant increase in GBS infections that greatly impact health and economics. Gap statement.
Wajeeorn Ouancharee, Anusak Kerdsin, Hien Van Doan, Chanagun Chitmanat, Kiatichai Faksri, Aroonlug Lulitanond, Aroonwadee Chanawong, Nicha Charoensri   +7 more
openaire   +2 more sources

Global dissemination of conjugative virulence plasmids co-harboring hypervirulence and multidrug resistance genes in Klebsiella pneumoniae

mSystems
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKp) has led to a high mortality rate in the clinical setting and garnered significant attention in the clinical and scientific communities.
Qi Xu, Ruanyang Sun, Xiaoxuan Liu, Heng Heng, Xuemei Yang, Miaomiao Xie, Chen Yang, Lianwei Ye, Edward Wai-Chi Chan, Rong Zhang, Sheng Chen   +10 more
doaj   +1 more source

Neutrophil function in hypervirulent Klebsiella pneumoniae infection [PDF]

The Lancet Microbe, 2022
Guan Yang, Qi Xu, Sheng Chen
openaire   +3 more sources

A Step Forward in Hypervirulent Klebsiella pneumoniae Diagnostics

Emerging Infectious Diseases
Hypervirulent Klebsiella pneumoniae (hvKp) can cause life-threatening infections in healthy community members. HvKp infections often involve multiple sites, some of which are unusual for classical K. pneumoniae (cKp) infections, such as the central nervous system, eyes, and fascia.
Thomas A. Russo, Francois Lebreton, Patrick T. McGann   +2 more
openaire   +3 more sources