Results 51 to 60 of about 3,484 (175)

Molecular epidemiology and genetic dynamics of carbapenem-resistant hypervirulent Klebsiella pneumoniae in China

Frontiers in Cellular and Infection Microbiology
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CRhvKP) poses a significant global health threat due to its enhanced virulence and resistance. This study analyzed 5,036 publicly available K.
Xiangchen Li, Xiangchen Li, Xiangchen Li, Sisi Chen, Sisi Chen, Yewei Lu, Yewei Lu, Weifeng Shen, Weifeng Shen, Weixin Wang, Weixin Wang, Junli Gao, Junli Gao, Junshun Gao, Junshun Gao, Pingyang Shao, Pingyang Shao, Zhuxian Zhou   +17 more
doaj   +1 more source

Facing Antimicrobial Resistance and Virulence in Streptococcus agalactiae During Late Pregnancy: Evaluation of Lactobacilli as a Supportive Approach

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Integrated phenotypic, genotypic, and functional characterization of clinical Streptococcus agalactiae (Group B streptococcus, GBS) isolates from maternal carriage. Combination of selected Lactobacillus species effectively antagonize S. agalactiae by limiting bacterial growth, preserving epithelial cell viability, and reducing pathogen adhesion ...
Astri D. Tagueha, Giulia Radocchia, Daniela Scribano, Matteo Lo Scalzo, Giacinto Panella, Serena Schippa, Giovanni Gherardi, Roberta Creti, Ilaria Marani, Giovanna Alfarone, Monica Imperi, Massimiliano Marazzato, Lucia Nencioni, Paola Checconi, Dolores Limongi, Anna Teresa Palamara, Cecilia Ambrosi   +16 more
wiley   +1 more source

Hypervirulent Klebsiella pneumoniae ST23: Hypervirulence Meets Antimicrobial Resistance

eMicrobe
Hypervirulent Klebsiella pneumoniae can cause community-acquired invasive infections such as pyogenic liver abscess and endophthalmitis in healthy individuals compared to the classical K. pneumoniae, causing opportunistic healthcare-associated infections. Globally, K.
Atsushi Togawa, L. Kristopher Siu
openaire   +1 more source

Sequence-Based Genomic Analysis Reveals Transmission of Antibiotic Resistance and Virulence among Carbapenemase-Producing Klebsiella pneumoniae Strains

mSphere, 2022
Carbapenemase-producing Klebsiella pneumoniae (CP-Kpn) are a major concern for nosocomial infections. We previously reported an intensive care unit (ICU) outbreak of CP-Kpn.
Yi Zhang, Chen Chen, Jing Wu, Jialin Jin, Tao Xu, Yang Zhou, Peng Cui, Jiazhen Chen, Shu Chen, Ning Jiang, Wenhong Zhang   +10 more
doaj   +1 more source

Hypervirulent Klebsiella pneumoniae Infections: A Systematic Review of Clinical, Microbiological, and Outcome Data From Reported Cases

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Distribution of organ involvement in reported hypervirulent Klebsiella pneumoniae cases. Studies restricted to isolated liver abscess cases were excluded. Percentages represent the proportion of cases with documented involvement of each anatomical site among cases with available data.
Nermin Sakru, Ender Cetinkaya, Feza Irem Aldi, Mervenur Inan, Canan Eryildiz   +4 more
wiley   +1 more source

Multiplex visual nucleic acid detection via isothermal cascaded transcription of fluorescent RNA aptamers

VIEW, Volume 7, Issue 3, June 2026.
(1) Existing multiplex nucleic acid detection struggles to combine high sensitivity, visual readout, and instrument‐free use, which is vital for rapid infection and antibiotic resistance diagnosis. (2) We developed MAGIC, integrating isothermal cascaded amplification and fluorescent RNA aptamer transcription, achieving 10 aM sensitivity, 100% accuracy ...
Yu Tang, Na Luo, Binbin Xie, Jie Luo, Yaling Yuan, Junjie Fan, Zhiyong Liu, Haiyan Gao, Ming Chen, Kai Chang   +9 more
wiley   +1 more source

Occurrence of colistin-resistant hypervirulent Klebsiella variicola [PDF]

Journal of Antimicrobial Chemotherapy, 2018
A colistin-resistant mucoid Klebsiella strain was recovered from the blood of a patient in China. Hypervirulence has been reported in Klebsiella pneumoniae, but not in other Klebsiella spp. The strain was suspected to be hypervirulent and was therefore characterized.The strain was subjected to genome sequencing using both the short-read Illumina HiSeq ...
Yang Lu, Yu Feng, Alan McNally, Zhiyong Zong   +3 more
openaire   +2 more sources

Neonatal Sepsis: The Impact of Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae

Frontiers in Medicine, 2021
The convergence of a vulnerable population and a notorious pathogen is devastating, as seen in the case of sepsis occurring during the first 28 days of life (neonatal period).
Subhankar Mukherjee, Shravani Mitra, Shanta Dutta, Sulagna Basu   +3 more
doaj   +1 more source

Genomic Insights Into Carbapenem‐Resistant Klebsiella pneumoniae in Pediatric Bloodstream Infections in Zhejiang, China (2019–2024)

Journal of Clinical Laboratory Analysis, Volume 40, Issue 10, May 2026.
The primary mechanism of carbapenem resistance identified in pediatric CRKP‐BSI strains was the production of Class B metalloenzymes. We report, for the first time, an outbreak of bloodstream infections in a neonatal ward caused by the dissemination of NDM‐1‐producing ST25 K. pneumoniae.
Mingming Zhou, Xiucai Zhang, Zhenjie Chen, Chao Fang, Shixing Liu, Jintao Xia, Yining Zhao, Chenmei Zhang, Hongqiang Shen   +8 more
wiley   +1 more source

Sputum Gram stain of hypervirulent Klebsiella pneumoniae

Journal of General and Family Medicine, 2023
Hypervirulent Klebsiella pneumoniae has virulence genes relevant to capsule overproduction, which could lead to the finding of thick transparent area ("halo") in Gram stain. In sputum Gram stain, observation of a large Gram-negative rod with a thick capsule may not only indicate that it is K. pneumoniae but also that it is a highly virulent strain.
Yuji Nishihara, Takahito Nakamura, Yuki Suzuki, Kei Kasahara   +3 more
openaire   +3 more sources