Results 121 to 130 of about 19,274 (215)

Molecular mechanisms responsible KPC-135-mediated resistance to ceftazidime-avibactam in ST11-K47 hypervirulent Klebsiella pneumoniae

Emerging Microbes and Infections
Ceftazidime-avibactam resistance attributable to the blaKPC-2 gene mutation is increasingly documented in clinical settings. In this study, we characterized the mechanisms leading to the development of ceftazidime-avibactam resistance in ST11-K47 ...
Qingyu Shi, Siquan Shen, Chengkang Tang, Li Ding, Yan Guo, Yang Yang, Shi Wu, Renru Han, Dandan Yin, Fupin Hu   +9 more
doaj   +1 more source

Laboratory Focus on Improving the Culture of Biosafety: Statewide Risk Assessment of Clinical Laboratories That Process Specimens for Microbiologic Analysis [PDF]

, 2018
The Wisconsin State Laboratory of Hygiene challenged Wisconsin laboratories to examine their biosafety practices and improve their culture of biosafety.
Batemman, Allen C., Beck, eric, Block, Timothy K., Bowles, Erin J., Dern, Richard, Kropp, Joshua L., Munson, Erik, Podzorski, Raymond P., Radke, Tyler, Siebers, Karen, Simmons, Brian, Smith, Mary A., Spray-Larson, Frances, Warshauer, David M.   +13 more
core   +1 more source

Nationwide surveillance of ribotypes and antimicrobial susceptibilities of toxigenic Clostridium difficile isolates with an emphasis on reduced doxycycline and tigecycline susceptibilities among ribotype 078 lineage isolates in Taiwan

Infection and Drug Resistance, 2018
Yuan-Pin Hung,1–3,* Pei-Jane Tsai,4,* Yuan-Ti Lee,5,6 Hung-Jen Tang,7 Hsiao-Ju Lin,1–3 Hsiu-Chuan Liu,1 Jen-Chieh Lee,2 Bo-Yang Tsai,4 Po-Ren Hsueh,8 Wen-Chien Ko2,9,10 1Department of Internal Medicine, Tainan Hospital, Ministry of Health and
Hung YP, Tsai PJ, Lee YT, Tang HJ, Lin HJ, Liu HC, Lee JC, Tsai BY, Hsueh PR, Ko WC   +9 more
doaj  

Overexpression and purification of YidRv gene from the hypervirulent Klebsiella pneumoniae, and the ability of the gene product in inducing a humoral response

Indonesian Journal of Biotechnology
The yidRv gene, isolated from the hypervirulent Klebsiella pneumoniae (hvKP), is a novel gene with an unknown function; however, it has exhibited high homology to the yidR, a gene recognized as potential vaccine candidate.
Tri Yudani Mardining Raras, Mauludy Jutta Ajrullah, Ellen Fenix Gunawan, Nadya Shafa Pramesti, Sumarno Reto Prawiro, Agustin Krisna Wardani, Is Helianti   +6 more
doaj   +1 more source

Emergence of Hypervirulent Ceftazidime/Avibactam-Resistant Klebsiella pneumoniae Isolates in a Chinese Tertiary Hospital

Infection and Drug Resistance, 2020
Dan Li,1,2,* Wenjian Liao,1,2,* Hai-hua Huang,3 Fang-ling Du,4 Dan-dan Wei,4 Yan-fang Mei,4 Dan Long,4 La-gen Wan,4 Yang Liu,4 Wei Zhang1 1Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Nanchang University, Nanchang ...
Li D, Liao W, Huang H, Du F, Wei D, Mei Y, Long D, Wan L, Liu Y, Zhang W   +9 more
doaj  

Hypervirulent Klebsiella pneumoniae in a South African tertiary hospital—Clinical profile, genetic determinants, and virulence in Caenorhabditis elegans

Frontiers in Microbiology
IntroductionA distinct strain of Klebsiella pneumoniae (K. pneumoniae) referred to as hypervirulent (hvKp) is associated with invasive infections such as pyogenic liver abscess in young and healthy individuals.
Likhona Dingiswayo, Olusesan Adeyemi Adelabu, Emmanuel Arko-Cobbah, Carolina Pohl, Nthabiseng Zelda Mokoena, Morne Du Plessis, Jolly Musoke, Jolly Musoke   +7 more
doaj   +1 more source

Characterization of Clostridium difficile 027 strains from an outbreak in a Portuguese hospital [PDF]

, 2012
C. difficile infection (CDI) is the cause of an intestinal disease mediated by two potent cytotoxins, TcdA and TcdB. Symptoms of CDI can range from asymptomatic colonization or mild diarrhea, to life-threatening inflammatory lesions such as ...
Antunes, Wilson, Henriques, Adriano O., Oleastro, Mónica, Pereira, Fátima, Rodrigues, João, Santos, Andrea, Serrano, Mónica   +6 more
core  

Hypervirulent knockout [PDF]

Genome Biology, 2001
openaire   +1 more source

Polymyxin-resistant hypervirulent Klebsiella pneumoniae clinical isolates from a tertiary hospital in China: molecular mechanisms, antimicrobial susceptibility, and virulent phenotypes

Frontiers in Microbiology
BackgroundPolymyxins are critical last-resort treatments for infections caused by multidrug-resistant (MDR) gram-negative bacteria, especially carbapenem-resistant isolates. Recently, there has been a continuous increase in reports of polymyxin-resistant
Xinyu Zhu, Jie Yan, Xiyun Lai, Tingjian Zou, Mengyuan Chen, Xiaofang Tang, Qiang Wang, Yuzhou He   +7 more
doaj   +1 more source

Cloning and Characterization of the Cell Wall Acting Enzyme CD1034 from the Pathogen Clostridium difficile [PDF]

, 2012
The manifestation of multidrug resistance in bacteria over the past several decades has resulted in one of the foremost challenges in the management of infectious diseases.
Suter, Zachary
core   +1 more source