Results 101 to 110 of about 13,389 (213)

Comparative Whole-Genomic Analysis of an Ancient L2 Lineage Mycobacterium tuberculosis Reveals a Novel Phylogenetic Clade and Common Genetic Determinants of Hypervirulent Strains

Frontiers in Cellular and Infection Microbiology, 2018
Background: Development of improved therapeutics against tuberculosis (TB) is hindered by an inadequate understanding of the relationship between disease severity and genetic diversity of its causative agent, Mycobacterium tuberculosis.
Rahim Rajwani, Wing Cheong Yam, Ying Zhang, Yu Kang, Barry Kin Chung Wong, Kenneth Siu Sing Leung, Kingsley King Gee Tam, Ketema Tafess Tulu, Li Zhu, Gilman Kit Hang Siu   +9 more
doaj   +1 more source

Emergence of a novel sequence type carbapenem-resistant hypervirulent Klebsiella pneumoniae ST6417 harboring blaNDM-5 on the lncX3 plasmid

Microbiology Spectrum
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) is a significant pathogen causing major public health problems worldwide. This study characterized a novel sequence type 6417 (ST6471) CR-hvKP strain recovered from the blood of a male ...
Junnian Liu, Sue Yuan, Luhan Xuan, Yu Sun, Xinyu Zhang, Lu Qiao, Xuefei Du   +6 more
doaj   +1 more source

Comparative Genomic Analysis of Hypervirulence Carbapenem-Resistant Klebsiella pneumoniae from Inpatients with Infection and Gut Colonization, China

Infection and Drug Resistance, 2023
Wan He,1,* Changbu Wu,2,3,* Guanping Chen,2– 4 Guili Zhang,2,3 Zihan Zhao,2,3 Shu’an Wen,2,3 Yuan Zhou,2,3 Xue Deng,2,3 Yu Feng,2,3 Lan-Lan Zhong,2,3 Guo-Bao Tian,2– 4 Min Dai1 1School of Laboratory Medicine, Chengdu Medical College, Chengdu ...
He W, Wu C, Chen G, Zhang G, Zhao Z, Wen S, Zhou Y, Deng X, Feng Y, Zhong LL, Tian GB, Dai M   +11 more
doaj  

Dietary Probiotics Improve Growth, Immunity and Disease Resistance in Fish Against Aeromonas hydrophila Infection

Aquaculture, Fish and Fisheries, Volume 6, Issue 2, April 2026.
Probiotics offer a promising alternative to antibiotics for managing Aeromonas hydrophila infections in aquaculture. Dietary supplementation of probiotics increases fish health, growth performance, and immune responses, while reducing antibiotic reliance in fish farming.
Md. Ridwanul Islam, Md. Adnan Sajib, Nurunnahar Nadira, Alokesh Kumar Ghosh   +3 more
wiley   +1 more source

Case fatality associated with a hypervirulent strain in patients with culture-positive Clostridium difficile infection: a retrospective population-based study

, 2012
SummaryBackgroundClostridium difficile is a major infectious cause of healthcare-associated diarrhea. The epidemiology of C. difficile infection (CDI) is changing, with evidence of increased incidence and severity.
Tissari, Päivi, Aittoniemi, Janne, Syrjänen, Jaana, Vuento, Risto, Huttunen, Reetta   +4 more
core   +1 more source

Gut Commensal Klebsiella pneumoniae Extracellular Vesicles Shape a Liver Microenvironment Conducive to Gut‐Liver Bacterial Translocation and Pro‐Tumorigenic Processes

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT Bacterial extracellular vesicles (EVs) are emerging mediators of host–microbe communication; however, their role in human disease remains unclear. Here, we identify two bacterial small tRNAs (tsRNAs) enriched in gut commensal Klebsiella pneumoniae‐derived EVs (KpEVs) that are markedly elevated in the serum of patients with hepatocellular ...
Shogo Tsubaki, Sho Nashimoto, Rika Tanaka, Touya Toyomoto, Hiroyasu Tsutsuki, Ken Kato, Jun Nakayama, Kiminori Kimura, Kazuki Oshima, Yusuke Yamamoto, Takuji Okusaka, Minoru Esaki, Nobuhiro Kawai, Nobuyuki Ota, Yusuke Yoshioka, Takahiro Ochiya, Yoshimasa Saito, Tomohiro Sawa, Katsuto Hozumi, Juntaro Matsuzaki, Hitoshi Tsugawa   +20 more
wiley   +1 more source

Rhabdomyolysis secondary to hypervirulent Klebsiella pneumoniae infection: A case report

, 2022
Hypervirulent Klebsiella pneumoniae (hvKP) is recognized as a lifethreatening community‐acquired infection associated with pyogenic liver abscess. However, rhabdomyolysis secondary to hvKP infection is rare.
Taiju Miyagami, Toshio Naito, Keiko Taga, Naoko Niimi, Chieko Mitaka   +4 more
core   +1 more source

High prevalence of KPC-2-producing hypervirulent Klebsiella pneumoniae causing meningitis in Eastern China

, 2019
Min Xu,1,* Yiqi Fu,2,* Yunhui Fang,3 Hao Xu,3 Haishen Kong,3 Yanchao Liu,1 Yu Chen,1,3 Lanjuan Li3 1Key Laboratory of Clinical In Vitro Diagnostic Techniques of Zhejiang Province, Center of Clinical Laboratory, The First Affiliated Hospital, College of ...
Fang Y, Liu Y, Xu M, Fu Y, Chen Y, Xu H, Li L, Kong H   +7 more
core  

Genome assemblies: Horizontal transfer of pOXA-48 from a hypervirulent Klebsiella pneumoniae ST23/KL57 to Serratia marcescens

, 2023
Hypervirulent Klebsiella pneumonia isolates express a range of virulence factors, often encoded on virulence plasmids. Occasionally these hypervirulent lineages acquire antimicrobial resistance genes rendering them multidrug-resistant.
Maria-Anna Misiakou, Kristian Schønning, Henrik Hasman, Karen Leth Nielsen, Susanne Häussler, Marc Sørensen, Frederik Boëtius Hertz, Marie Helleberg   +7 more
core   +1 more source

Antibiotic Susceptibility Profile of Carbapenem-Resistant Klebsiella pneumoniae Isolated from Clinical Specimens in Iraq

Medical Journal of Babylon
Background: Infections caused by carbapenem-resistant Klebsiella pneumoniae (CR-Kp) isolates are a major threat to public health. Antibiotic misuse and overuse lead to the emergence of CR-Kp.
Ali A. Al-Shammari, Alaa H. Al-Charrakh
doaj   +1 more source