Results 81 to 90 of about 13,389 (213)

Whole Genome Characterization of Klebsiella Strains in European Hedgehogs and Human Nosocomial Settings Identified Shared Sequence Types, Antimicrobial Resistance Genes and Plasmids

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Klebsiella pneumoniae is a pathogen associated with healthcare‐acquired infections and antimicrobial resistance (AMR) to beta‐lactams and carbapenems. Although wild animals are not typically exposed to antibiotics, they can harbour resistant strains. The European hedgehog (Erinaceus europaeus) is increasingly found in urban areas,
Biel Garcias, Chiara Seminati, Carolin M. Kobras, Samuel K. Sheppard, Rafael A. Molina‐López, Laila Darwich   +5 more
wiley   +1 more source

Sputum Gram stain of hypervirulent Klebsiella pneumoniae

Journal of General and Family Medicine, 2023
Hypervirulent Klebsiella pneumoniae has virulence genes relevant to capsule overproduction, which could lead to the finding of thick transparent area ("halo") in Gram stain. In sputum Gram stain, observation of a large Gram-negative rod with a thick capsule may not only indicate that it is K. pneumoniae but also that it is a highly virulent strain.
Yuji Nishihara, Takahito Nakamura, Yuki Suzuki, Kei Kasahara   +3 more
openaire   +3 more sources

Additional file 3 of Comparative in silico characterization of Klebsiella pneumoniae hypervirulent plasmids and their antimicrobial resistance genes

, 2022
Additional file 3. Fig. 1. The ARGs cassettes surrounding class 1 integron in Klebsiella pneumoniae hypervirulent plasmids. Fig. 2.
Anam Naz (800890), Negin Bolourchi (11599557), Maryam Sohrabi (12754337), Farzad Badmasti (9327920)   +3 more
core   +1 more source

Interplay Between Virulence Genes, Antimicrobial Resistance Profiles, and Biofilm Formation in Klebsiella pneumoniae Causing Urinary Tract Infections in North Lebanon

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
– Figure design (single panel) Central icon: K. pneumoniae cell Left panel – Virulence genes (icons): Adhesion: fimH, mrkD → strong biofilm Capsule/regulation: magA, rmpA Siderophores: entB, iucA → iron uptake Right panel – Outcomes: Biofilm strength (weak → strong gradient) Antibiotic resistance (ESBL, MDR) Bottom split: Hospital‐acquired → strong ...
Mazen Zaylaa, Rayan Farha, Jana Taleb, Amal Saad, Omar El Gharbawy, Ricardo Sarraf, Ibtihal Kassam, Chadi Hamdach, Nisrine Bissar   +8 more
wiley   +1 more source

Hypervirulent Clostridium difficile ribotypes are CpG depleted

, 2018
Hypervirulent Clostridium difficile ribotypes are CpG ...
Vinay Kamuju (5711696), Santosh Kumar (106550), Wajihul Hasan Khan (5143376), Perumal Vivekanandan (698238)   +3 more
core   +1 more source

Immune modulations and survival strategies of evolved hypervirulent Salmonella Typhimurium strains

, 2020
Background Evolving multidrug-resistance and hypervirulence in Salmonella is due to multiple host-pathogen, and non-host environmental interactions. Previously we had studied Salmonella adaptation upon repeated exposure in different in-vitro and in-vivo
Negi, Vidya Devi, Mishra, Abtar, Pradhan, Diana, Chakravortty, Dipshikha, Diana Pradhan, Pradhan, Jasmin, Rohan Dhiman, Abtar Mishra, Dhiman, Rohan, Dipshikha Chakravortty, Karmakar, Kapudeep, Jasmin Pradhan, Kapudeep Karmakar, Vidya Devi Negi   +13 more
core   +1 more source

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

MedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang, Jingfei Shi, Linlin Xu, Guangrui Zhao, Yue Chen, Lin Cheng, Xiaokang Li, Zhigang Sun, Shuhong Huang   +8 more
wiley   +1 more source

Molecular characterization of hybrid virulence plasmids in ST11-KL64 KPC-2-producing multidrug-resistant hypervirulent Klebsiella pneumoniae from China

Frontiers in Microbiology
IntroductionCarbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-HvKP) strains combining virulence and multidrug resistance (MDR) features pose a great public health concern. The aim of this study is to explore the evolutionary characteristics of
Fushan Zhang, Leyuan Li, Leyuan Li, Yuxin Zhao, Yuxin Zhao, Huiyue Dong, Huiyue Dong, Buhui Zhao, Buhui Zhao, Xiaoyu Zhao, Xiaoyu Zhao, Ziwei Xia, Ziwei Xia, Leizi Chi, Leizi Chi, Yan Wang, Yan Wang, Ruichao Li, Shangshang Qin, Shangshang Qin, Xiangjing Fu, Xiangjing Fu   +21 more
doaj   +1 more source

Carbapenem Resistance Conferred by OXA-48 in K2-ST86 Hypervirulent Klebsiella pneumoniae , France

, 2020
International audienceWe recovered 2 carbapenem-resistant K2-ST86 hypermucoviscous Klebsiella pneumoniae isolates from patients in France. The isolates had genetic attributes of hypervirulent K. pneumoniae but differed in ability to cause mouse lethality.
Beyrouthy, Racha, Robin, Frédéric, Bonnet, Richard, Dalmasso, Guillaume, Birer, Aurélien   +4 more
core   +1 more source

Multiplex visual nucleic acid detection via isothermal cascaded transcription of fluorescent RNA aptamers

VIEW, Volume 7, Issue 3, June 2026.
(1) Existing multiplex nucleic acid detection struggles to combine high sensitivity, visual readout, and instrument‐free use, which is vital for rapid infection and antibiotic resistance diagnosis. (2) We developed MAGIC, integrating isothermal cascaded amplification and fluorescent RNA aptamer transcription, achieving 10 aM sensitivity, 100% accuracy ...
Yu Tang, Na Luo, Binbin Xie, Jie Luo, Yaling Yuan, Junjie Fan, Zhiyong Liu, Haiyan Gao, Ming Chen, Kai Chang   +9 more
wiley   +1 more source