Results 71 to 80 of about 14,652 (219)

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Characterization of hypervirulent Klebsiella pneumoniae isolates in Belgium

European Journal of Clinical Microbiology & Infectious Diseases, 2022
Hypervirulent Klebsiella pneumoniae (hvKp) raised concern worldwide. We studied 22 hvKp clinical invasive isolates referred to the Belgian national reference laboratory between 2014 and 2020. Sixty-four percent of the isolates expressed K2 capsular serotype and belonged to 7 different MLST lineages, while 32% expressed K1 (all belonging to ST23) and ...
Anantharajah, Ahalieyah, Deltombe, Matthieu, de Barsy, Marie, Evrard, Stephanie, Denis, Olivier, Bogaerts, Pierre, Hallin, Marie, Miendje Deyi, Véronique Yvette, Piérard, Denis, Bruynseels, Peggy, Boelens, Jerina, Glupczynski, Youri, Huang, Te-Din   +12 more
openaire   +3 more sources

Molecular characterization of hybrid virulence plasmids in ST11-KL64 KPC-2-producing multidrug-resistant hypervirulent Klebsiella pneumoniae from China

Frontiers in Microbiology
IntroductionCarbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-HvKP) strains combining virulence and multidrug resistance (MDR) features pose a great public health concern. The aim of this study is to explore the evolutionary characteristics of
Fushan Zhang, Leyuan Li, Leyuan Li, Yuxin Zhao, Yuxin Zhao, Huiyue Dong, Huiyue Dong, Buhui Zhao, Buhui Zhao, Xiaoyu Zhao, Xiaoyu Zhao, Ziwei Xia, Ziwei Xia, Leizi Chi, Leizi Chi, Yan Wang, Yan Wang, Ruichao Li, Shangshang Qin, Shangshang Qin, Xiangjing Fu, Xiangjing Fu   +21 more
doaj   +1 more source

Serotypic and Genomic Diversity of Vibrio anguillarum in Rainbow Trout Farms in Turkey: Implications for Vibriosis Control and Vaccine Candidate Selection

Journal of Fish Diseases, Volume 49, Issue 10, October 2026.
ABSTRACT Outbreaks of vibriosis caused by Vibrio anguillarum are a persistent constraint on rainbow trout (Oncorhynchus mykiss) aquaculture. However, information on the population structure of field strains in Turkey has been lacking. Here, we report the first systematic serotypic, proteomic, and genomic characterization of 23 V.
Soner Altun, Muhammed Duman, Jesús L. Romalde, Nihed Ajmi, Gorkem Tasci, Cuneyt Ozakin, Nazmiye Ulku Tuzemen, Bekir Akça, Sebahattin Ergün, Sevdan Yılmaz, Izzet Burcin Saticioglu   +10 more
wiley   +1 more source

Additional file 3 of Comparative in silico characterization of Klebsiella pneumoniae hypervirulent plasmids and their antimicrobial resistance genes

, 2022
Additional file 3. Fig. 1. The ARGs cassettes surrounding class 1 integron in Klebsiella pneumoniae hypervirulent plasmids. Fig. 2.
Anam Naz (800890), Negin Bolourchi (11599557), Maryam Sohrabi (12754337), Farzad Badmasti (9327920)   +3 more
core   +1 more source

Whole genome sequencing reveals significant intra-hospital clonal transmission and a potential multidrug resistant and hypervirulent sequence cluster of Corynebacterium striatum

Emerging Microbes and Infections
With increasing reports about Corynebacteritum straitum, its role as an emerging human pathogen is been recognized. However, few studies have explored the genomic epidemiology of C. straitum in China.
Menglan Zhou, Jiawei Chen, Tingting Zhang, Lingli Liu, Jingjia Zhang, Wei Kang, Hongtao Dou, Dingding Li, Lina Guo, Ying Zhao, Yali Liu, Renyuan Zhu, Hongli Sun, Zhengyin Liu   +13 more
doaj   +1 more source

Revisiting the Molecular Roadmap for Sugar Crops: Genome Reading, Trait Writing and Variety Redesigning

Plant Biotechnology Journal, Volume 24, Issue 9, Page 5013-5040, September 2026.
ABSTRACT Sugar crops, including but not limited to sugarcane, sugar beet, sweet sorghum and stevia, are major sources of sugar production in the world. However, conventional breeding approaches, limited by long breeding cycles, low efficiency and restricted capacity to improve complex traits in sugar crops, are increasingly insufficient to address the ...
Peilin Wang, Qibin Wu, Wenzhi Wang, Prakash Lakshmanan, Yangrui Li, Khushi Muhammad, Yuguang Wang, Youxiong Que   +7 more
wiley   +1 more source

Hypervirulent Clostridium difficile ribotypes are CpG depleted

, 2018
Hypervirulent Clostridium difficile ribotypes are CpG ...
Vinay Kamuju (5711696), Santosh Kumar (106550), Wajihul Hasan Khan (5143376), Perumal Vivekanandan (698238)   +3 more
core   +1 more source

Carbapenem Resistance Conferred by OXA-48 in K2-ST86 Hypervirulent Klebsiella pneumoniae , France

, 2020
International audienceWe recovered 2 carbapenem-resistant K2-ST86 hypermucoviscous Klebsiella pneumoniae isolates from patients in France. The isolates had genetic attributes of hypervirulent K. pneumoniae but differed in ability to cause mouse lethality.
Beyrouthy, Racha, Robin, Frédéric, Bonnet, Richard, Dalmasso, Guillaume, Birer, Aurélien   +4 more
core   +1 more source

Occurrence of colistin-resistant hypervirulent Klebsiella variicola [PDF]

Journal of Antimicrobial Chemotherapy, 2018
A colistin-resistant mucoid Klebsiella strain was recovered from the blood of a patient in China. Hypervirulence has been reported in Klebsiella pneumoniae, but not in other Klebsiella spp. The strain was suspected to be hypervirulent and was therefore characterized.The strain was subjected to genome sequencing using both the short-read Illumina HiSeq ...
Yang Lu, Yu Feng, Alan McNally, Zhiyong Zong   +3 more
openaire   +2 more sources