Results 91 to 100 of about 19,274 (215)

Hypervirulent Klebsiella pneumoniae – clinical and molecular perspectives [PDF]

Journal of Internal Medicine, 2019
AbstractHypervirulent Klebsiella pneumoniae (hvKp) has emerged as a concerning global pathogen. hvKp is more virulent than classical K. pneumoniae (cKp) and capable of causing community‐acquired infections, often in healthy individuals. hvKp is carried in the gastrointestinal tract, which contributes to its spread in the community and healthcare ...
J. E. Choby, J. Howard‐Anderson, D. S. Weiss   +2 more
openaire   +2 more sources

Risk factors for recurrence in patients with Clostridium difficile infection due to 027 and non-027 ribotypes [PDF]

, 2018
Objectives: Our objective was to evaluate factors associated with recurrence in patients with 027+ and 027– Clostridium difficile infection (CDI). Methods: Patients with CDI observed between January and December 2014 in six hospitals were consecutively ...
Aceti, A., Andreoni, M., Antonelli, G., Carfagna, P., Cauda, R., Delle Rose, D., Falcone, M., Fantoni, M., Farcomeni, A., Fontana, C., Goldoni, P., Iraci, F., Mastroianni, C., Murri, R., Petrosillo, N., Raponi, G., Sanguinetti, M., Santino, I., Tiseo, G., Venditti, M.   +19 more
core   +1 more source

Antimycobacterial and Nitric Oxide Production Inhibitory Activities of Goyazensolide and Centratherin Isolated From Eremanthus crotonoides by High‐Speed Countercurrent Chromatography

Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.
ABSTRACT In this study, bioassay‐guided fractionation of the ethanolic extract from Eremanthus crotonoides leaves enabled the isolation of two bioactive sesquiterpene lactones, centratherin and goyazensolide, which were evaluated for their antimycobacterial and anti‐inflammatory properties.
Natalie Giovanna da Rocha Ximenes, Sanderson Dias Calixto, Thatiana Lopes Biá Ventura Simão, Elena B. Lassunskaia, Patrícia de Homobono de Brito Moura, Ivana Ramos Correa Leal, Michelle Frazão Muzitano, Shaft Corrêa Pinto   +7 more
wiley   +1 more source

A Case Series of Hypermucoid Klebsiella pneumoniae Liver Abscess in Caucasian Americans Without Travel History: An Epidemiologic Shift?

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Hypervirulent Klebsiella pneumoniae (hvKp) is an emerging cause of community‐acquired pyogenic liver abscess (PLA), classically described in East and Southeast Asia. We report two cases of hvKp‐associated PLA in Caucasian women of American origin with no history of international travel, animal exposure, or Asian food consumption. Both patients
Krishna Sai Kiran Sakalabaktula, Sameer Kumar Majety, Sri Ratna Divya Nanduri, Divya Durga, David Kreps, Devi Prasad Botu, Gopichand Muppana   +6 more
wiley   +1 more source

Effects of the COVID-19 pandemic on clinical manifestations and therapeutic outcomes in acute endophthalmitis

Journal of Mind and Medical Sciences
Endophthalmitis incidence and clinical characteristics was reported to change during Covid-19 pandemic, due to multiple influencing factors, such as prolonged lockdown periods, persistent immune suppression following Sars-Cov-2 infection, and mask ...
Ana Maria Dascalu, Sanda Jurja, Carmen Luminita Mocanu, Cristina Alexandrescu, Daniela Stana, Madalina Totir, Ece Ergin, Corneliu Tudor, Catalin Cicerone Grigorescu, Dragos Serban, Laurentiu Simion, Dan Dumitrescu, Andrei Marin, Catalin Teodor Constantinescu, Bogdan Mihai Cristea   +14 more
doaj   +1 more source

Comparative Whole-Genomic Analysis of an Ancient L2 Lineage Mycobacterium tuberculosis Reveals a Novel Phylogenetic Clade and Common Genetic Determinants of Hypervirulent Strains

Frontiers in Cellular and Infection Microbiology, 2018
Background: Development of improved therapeutics against tuberculosis (TB) is hindered by an inadequate understanding of the relationship between disease severity and genetic diversity of its causative agent, Mycobacterium tuberculosis.
Rahim Rajwani, Wing Cheong Yam, Ying Zhang, Yu Kang, Barry Kin Chung Wong, Kenneth Siu Sing Leung, Kingsley King Gee Tam, Ketema Tafess Tulu, Li Zhu, Gilman Kit Hang Siu   +9 more
doaj   +1 more source

Excess length of stay and mortality due to Clostridium difficile infection: a multi-state modelling approach. [PDF]

, 2014
BACKGROUND: The burden of healthcare-associated infections, such as healthcare-acquired Clostridium difficile (HA-CDI), can be expressed in terms of additional length of stay (LOS) and mortality. However, previous estimates have varied widely.
Cookson, B, Deeny, SR, Edmunds, WJ, Goldenberg, SD, Green, N, Jit, M, Robotham, JV, van Kleef, E   +7 more
core   +1 more source

Discovery of a Dual‐Target DNAzyme for Clostridioides difficile and Listeria monocytogenes Diagnostics

ChemistryEurope, Volume 4, Issue 3, March 2026.
A newly discovered fluorogenic DNAzyme, RFD‐CD3, enables rapid and sensitive detection of Clostridioides difficile and—unexpectedly—Listeria monocytogenes, making it the first dual‐responsive DNAzyme for two unrelated bacterial pathogens. Its strong catalytic efficiency, pH‐tolerant activity, and modular trans‐acting design position it as a promising ...
Soyeon Lee, Dingran Chang, Jimmy Gu, Bruno J. Salena, Yingfu Li   +4 more
wiley   +1 more source

Emergence of a novel sequence type carbapenem-resistant hypervirulent Klebsiella pneumoniae ST6417 harboring blaNDM-5 on the lncX3 plasmid

Microbiology Spectrum
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) is a significant pathogen causing major public health problems worldwide. This study characterized a novel sequence type 6417 (ST6471) CR-hvKP strain recovered from the blood of a male ...
Junnian Liu, Sue Yuan, Luhan Xuan, Yu Sun, Xinyu Zhang, Lu Qiao, Xuefei Du   +6 more
doaj   +1 more source

Comparative Genomic Analysis of Hypervirulence Carbapenem-Resistant Klebsiella pneumoniae from Inpatients with Infection and Gut Colonization, China

Infection and Drug Resistance, 2023
Wan He,1,* Changbu Wu,2,3,* Guanping Chen,2– 4 Guili Zhang,2,3 Zihan Zhao,2,3 Shu’an Wen,2,3 Yuan Zhou,2,3 Xue Deng,2,3 Yu Feng,2,3 Lan-Lan Zhong,2,3 Guo-Bao Tian,2– 4 Min Dai1 1School of Laboratory Medicine, Chengdu Medical College, Chengdu ...
He W, Wu C, Chen G, Zhang G, Zhao Z, Wen S, Zhou Y, Deng X, Feng Y, Zhong LL, Tian GB, Dai M   +11 more
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