Results 181 to 190 of about 14,652 (219)

Revisiting definitions of hypervirulent and classical Klebsiella pneumoniae through virulence factors and disease phenotype. [PDF]

open access: yesCommun Med (Lond)
Lee AL   +9 more
europepmc   +1 more source

Prevalence of multidrug-resistant hypervirulent Klebsiella pneumoniae without defined hypervirulent biomarkers in Anhui, China: a new dimension of hypervirulence

open access: yesFrontiers in Microbiology, 2023
Klebsiella pneumoniae is an opportunistic pathogen that mainly causes nosocomial infections and hospital-associated pneumonia in elderly and immunocompromised people. However, multidrug-resistant hypervirulent K. pneumoniae (MDR-hvKp) has emerged recently as a serious threat to global health that can infect both immunocompromised and healthy ...
Baolin Sun, Yujie Li, Zhien He
exaly   +4 more sources

A promising bioconjugate vaccine against hypervirulent Klebsiella pneumoniae [PDF]

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Hypervirulent Klebsiella pneumoniae (hvKp) is globally disseminating as a community-acquired pathogen causing life-threatening infections in healthy individuals.
Christian Harding   +2 more
exaly   +2 more sources

Hypervirulent Klebsiella pneumoniae

New England Journal of Medicine, 2021
Hypervirulent Klebsiella pneumoniae A 45-year-old man presented with eye pain and fever. Imaging showed multiple organ abscesses.
Qiong, Zou, Yang, Li
openaire   +2 more sources

Emergence of a hypervirulent carbapenem-resistant Klebsiella pneumoniae isolate from clinical infections in China

open access: yesJournal of Infection, 2015
Objectives: Hypervirulent Klebsiella pneumoniae (hvKP) infections occur worldwide, but carbapenem-resistant hvKP strain has rarely been observed. Methods: A retrospective study was conducted in 28 cases of carbapenem-resistant K.
Henan Li, Wenen Liu
exaly   +2 more sources

Hypervirulence and pathogen fitness

Trends in Microbiology, 2003
Historically, pathogenesis research has focused on the identification and characterization of virulence factors. More recently, 'anti-virulence' genes have been discovered. Mutations in these loci result in a hypervirulent phenotype, as measured by a lower lethal dose, a colonization advantage, reduced clearance or decreased survival time of the host ...
Amy K, Foreman-Wykert, Jeff F, Miller
openaire   +2 more sources

Pathogenesis of Hypervirulent Fowl Adenovirus Serotype 4: The Contributions of Viral and Host Factors

open access: yesViruses, 2019
Since 2015, severe outbreaks of hepatitis-hydropericardium syndrome (HHS), caused by hypervirulent fowl adenovirus serotype 4 (FAdV-4), have emerged in several provinces in China, posing a great threat to poultry industry. So far, factors contributing to
Jun Zhao, Zeng Wang
exaly   +2 more sources

Hypervirulent Klebsiella pneumoniae detection methods: a minireview

Archives of Microbiology, 2023
Hypervirulent Klebsiella pneumoniae (hvKp), characterized by high virulence and epidemic potential, has become a global public health challenge. Therefore, improving the identification of hvKp and enabling earlier and faster detection in the community to support subsequent effective treatment and prevention of hvKp are an urgent issue. To address these
Qi-Bin, Zhang   +6 more
openaire   +2 more sources

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