Results 191 to 200 of about 19,274 (215)
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Hypervirulence and pathogen fitness
Trends in Microbiology, 2003Historically, pathogenesis research has focused on the identification and characterization of virulence factors. More recently, 'anti-virulence' genes have been discovered. Mutations in these loci result in a hypervirulent phenotype, as measured by a lower lethal dose, a colonization advantage, reduced clearance or decreased survival time of the host ...
Amy K, Foreman-Wykert, Jeff F, Miller
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Indian Journal of Medical Microbiology
An emerging pathotype of Klebsiella pneumoniae, initially identified in Southeast Asian countries, has now spread to multiple countries, including India. These convergent strains, carrying both resistance and virulence determinants, are classified as multidrug-resistant Hypervirulent Klebsiella pneumoniae (MDR-HvKp).
Sanika Mahesh Kulkarni +7 more
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An emerging pathotype of Klebsiella pneumoniae, initially identified in Southeast Asian countries, has now spread to multiple countries, including India. These convergent strains, carrying both resistance and virulence determinants, are classified as multidrug-resistant Hypervirulent Klebsiella pneumoniae (MDR-HvKp).
Sanika Mahesh Kulkarni +7 more
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Seven hypervirulent ST380 Klebsiella pneumoniae septic localizations
Médecine et Maladies Infectieuses, 2017International ...
Hentzien, Maxime +5 more
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Primary osteomyelitis caused by hypervirulent Klebsiella pneumoniae
The Lancet Infectious Diseases, 2016Klebsiella pneumoniae is the most clinically relevant species of this genus, known to cause both community-acquired and nosocomial infections worldwide. In the past two decades, a distinct hypervirulent strain of K pneumoniae, characterised by its hypermucoviscous phenotype, has emerged as a clinically significant pathogen responsible for highly ...
Bonnie C, Prokesch +5 more
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Pediatric hypervirulent Klebsiella pneumoniae septic arthritis
Pediatrics International, 2016AbstractCases of infection with hypervirulent Klebsiella pneumoniae are gradually increasing in number, and cause life‐threatening community‐acquired infection even in immunocompetent patients. A 14‐year‐old boy developed septic hip arthritis due to hypervirulent K. pneumoniae (sequence type 23, serotype K1, magA positive). The patient initially seemed
Shun, Kishibe +11 more
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Biodiversity and hypervirulence of Listeria monocytogenes
Nature Genetics, 2016The integration of large, well-sampled collections of bacterial isolates with genomics and experimental methods provides opportunities for 'top-down' discovery of the genetic basis of phenotypes of interest. In a new report, the authors apply this approach to investigate the heterogeneity in manifestations of disease caused by Listeria monocytogenes ...
Yonatan H Grad, Sarah M Fortune
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Hypervirulent Klebsiella Pneumoniae Osteomyelitis in a Child
Pediatric Infectious Disease JournalAn 18-month-old boy presented with septic arthritis and osteomyelitis caused by Hypervirulent Klebsiella pneumoniae harboring cardinal virulence genes. The condition necessitated several surgical interventions, and a prolonged course of antibiotic therapy to effectively manage the severe infection and prevent complications, highlighting the challenges ...
Ryoichi Yamaki +6 more
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Genomic analysis of hypervirulent Klebsiella penumoniae
2023Hypervirulent Klebsiella pneumoniae is an important pathotype with enhanced virulence features,it usually causes life-threatening infections from community among young and healthy individuals. Liver abscess caused by hvKp has been increasingly reported in Asia, and is becoming a global disease during recent years.
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Emphysematous gastritis due to hypervirulent Klebsiella pneumoniae
The Lancet Infectious Diseases, 2022Naomi, Saeki +8 more
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Investigations of carbapenem resistant and hypervirulent Klebsiella pneumoniae
Acta Microbiologica et Immunologica HungaricaAbstractHypervirulent Klebsiella pneumoniae is an emerging pathogen that has gained attention due to its increased ability to cause infections even in healthy individuals. The aim of this study is to investigate virulence factors in K. pneumoniae strains isolated from clinical specimens and their association with carbapenem resistance.
El Mehdi Belouad +5 more
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