Results 191 to 200 of about 13,389 (213)
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Biodiversity and hypervirulence of Listeria monocytogenes
Nature Genetics, 2016The integration of large, well-sampled collections of bacterial isolates with genomics and experimental methods provides opportunities for 'top-down' discovery of the genetic basis of phenotypes of interest. In a new report, the authors apply this approach to investigate the heterogeneity in manifestations of disease caused by Listeria monocytogenes ...
Yonatan H Grad, Sarah M Fortune
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Hypervirulent Klebsiella Pneumoniae Osteomyelitis in a Child
Pediatric Infectious Disease JournalAn 18-month-old boy presented with septic arthritis and osteomyelitis caused by Hypervirulent Klebsiella pneumoniae harboring cardinal virulence genes. The condition necessitated several surgical interventions, and a prolonged course of antibiotic therapy to effectively manage the severe infection and prevent complications, highlighting the challenges ...
Ryoichi Yamaki +6 more
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Indian Journal of Medical Microbiology
An emerging pathotype of Klebsiella pneumoniae, initially identified in Southeast Asian countries, has now spread to multiple countries, including India. These convergent strains, carrying both resistance and virulence determinants, are classified as multidrug-resistant Hypervirulent Klebsiella pneumoniae (MDR-HvKp).
Sanika Mahesh Kulkarni +7 more
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An emerging pathotype of Klebsiella pneumoniae, initially identified in Southeast Asian countries, has now spread to multiple countries, including India. These convergent strains, carrying both resistance and virulence determinants, are classified as multidrug-resistant Hypervirulent Klebsiella pneumoniae (MDR-HvKp).
Sanika Mahesh Kulkarni +7 more
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Getting hypervirulent Klebsiella pneumoniae on the radar screen
Current Opinion in Infectious Diseases, 2018Purpose of review Two pathotypes of Klebsiella pneumoniae cause human infections, classical (cKp) and hypervirulent (hvKp) K. pneumoniae. The present understanding of genetic elements, the need for an accurate test to identify hvKp, the clinical implications of infection, the knowledge gap on how and why hvKp colonization ...
John A, Sellick, Thomas A, Russo
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Clostridium difficile: Emergence of Hypervirulence and Fluoroquinolone Resistance
Infection, 2007Clostridium difficile is a well-known cause of sporadic and healthcare-associated diarrhea. Multihospital outbreaks due to a single strain and outbreaks associated with antibiotic selective pressure, especially clindamycin, have been well documented. Severe cases and fatalities from C. difficile are uncommon.
B, Razavi +2 more
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Current Management Strategies for Hypervirulent Klebsiella
Infectious Disease Clinics of North AmericaHypervirulent Klebsiella pneumoniae (HvKp) is a highly invasive pathotype causing severe, community-acquired infections, unlike nosocomial classic K pneumoniae. First reported in 1986, HvKp is linked to liver abscess, bacteremia, and endophthalmitis, driven by K1/K2 polysaccharide capsule, hypermucoviscous capsule production and siderophores.
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Primary osteomyelitis caused by hypervirulent Klebsiella pneumoniae
The Lancet Infectious Diseases, 2016Klebsiella pneumoniae is the most clinically relevant species of this genus, known to cause both community-acquired and nosocomial infections worldwide. In the past two decades, a distinct hypervirulent strain of K pneumoniae, characterised by its hypermucoviscous phenotype, has emerged as a clinically significant pathogen responsible for highly ...
Bonnie C, Prokesch +5 more
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Emphysematous gastritis due to hypervirulent Klebsiella pneumoniae
The Lancet Infectious Diseases, 2022Naomi, Saeki +8 more
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Emergence of a hypervirulent neonatal pathogen
The Lancet Infectious Diseases, 2014openaire +2 more sources