Interdisciplinary MedicinePhotodynamic and photothermal therapy have emerged as standard treatments for a range of tumors and microvascular diseases. However, a significant gap remains in the clinical availability of photosensitizers.
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Enhancing the Photosensitivity of Hypocrellin A by Perylene Diimide Metallacage-Based Host–Guest Complexation for Photodynamic Therapy [PDF]
Nano-Micro LettersHighlights A new type of metallacage was successfully fabricated and used as containers for hypocrellin-type photosensitizers, which prevented the self-aggregation of photosensitizers in aqueous solution.
Rongrong Li +9 more
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Hypocrellin-Mediated PDT: A Systematic Review of Its Efficacy, Applications, and Outcomes [PDF]
International Journal of Molecular SciencesPhotodynamic therapy (PDT) is a light-activated treatment that generates reactive oxygen species (ROS) to induce microbial cell death. As resistance to traditional antibiotics intensifies globally, PDT has emerged as a promising alternative or adjunctive
Rafał Wiench +2 more
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LED Light-Activated Hypocrellin B Induces Mitochondrial Damage of Ovarian Cancer Cells
International Journal of Photoenergy, 2012 Objective. Hypocrellin is a natural photosensitizer from a traditional Chinese herb. In the present study, our aim is to investigate the effect of LED light-activated hypocrellin B on mitochondria of ovarian cancer cells. Material and Methods.
Yuan Jiang +3 more
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Effect of Light-Activated Hypocrellin B on the Growth and Membrane Permeability of Gram-Negative Escherichia coli Cells [PDF]
International Journal of Photoenergy, 2014 Aim. To investigate the effect of light-activated hypocrellin B on the growth and membrane permeability of Gram-negative bacteria. Methods. Escherichia coli (E.
Yuan Jiang +4 more
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Rubroshiraia gen. nov., a second hypocrellin-producing genus in Shiraiaceae (Pleosporales) [PDF]
MycoKeys, 2019 Shiraiaceae is an important family in Pleosporales (Dothideomycetes), which includes medical fungi and plant pathogens. Two hypocrellin-producing taxa, Shiraia bambusicola and a novel genus Rubroshiraia gen.
Dong-Qin Dai +13 more
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Fermentation, 2021 Hypocrellin is a natural 3,10-xylene-4,9-anthracene derivative compound that originates from the stroma of Shiraia bambusicola (S. bambusicola) and Hypocrella bambusae with excellent photobiological activities.
Xiaoxiao Yan +4 more
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Drug-delivery and multifunction possibilities of hypocrellin photosensitizers [PDF]
Journal of Innovative Optical Health Sciences, 2015 Photodynamic therapy (PDT) has been a routine treatment of tumors and some microvascular diseases, but clinically available photosensitizers are still scarce.
Hong Deng, Jie Xie, Jingquan Zhao
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Phylogenetic Position of Shiraia-Like Endophytes on Bamboos and the Diverse Biosynthesis of Hypocrellin and Hypocrellin Derivatives [PDF]
Journal of Fungi, 2021 The main active ingredients of the fruiting bodies of Shiraia bambusicola and Rubroshiraia bambusae are Hypocrellins, belonging perylenequinones with potential photodynamic activity against cancer and microbial diseases.
Xin Tong +4 more
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Effects of 5-Azacytidine on Growth and Hypocrellin Production of Shiraia bambusicola [PDF]
Frontiers in Microbiology, 2018 Hypocrellins, fungal perylenequinones of Shiraia bambusicola are developed as important photodynamic therapy agents against cancers and viruses. Due to the limitation of the wild resources, the mycelium culture is a promising alternative for hypocrellin ...
Yan Jun Ma, Can Song Lu, Jian Wen Wang
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