Results 41 to 50 of about 1,024 (191)

Genome Sequencing and Analysis of the Hypocrellin-Producing Fungus Shiraia bambusicola S4201

open access: yesFrontiers in Microbiology, 2020
Shiraia bambusicola has long been used as a traditional Chinese medicine and its major medicinal active metabolite is hypocrellin, which exhibits outstanding antiviral and antitumor properties.
Ning Zhao   +6 more
doaj   +1 more source

De Novo Transcriptome Assembly in Shiraia bambusicola to Investigate Putative Genes Involved in the Biosynthesis of Hypocrellin A

open access: yes, 2016
Shiraia bambusicola is a species of the monotypic genus Shiraia in the phylum Ascomycota. In China, it is known for its pharmacological properties that are used to treat rheumatic arthritis, sciatica, pertussis, tracheitis and so forth.
Xi Lin   +5 more
core   +1 more source

The signaling role of extracellular ATP in co-culture of Shiraia sp. S9 and Pseudomonas fulva SB1 for enhancing hypocrellin A production

open access: yesMicrobial Cell Factories, 2021
Background Adenosine 5′-triphosphate (ATP) plays both a central role as an intracellular energy source, and a crucial extracellular signaling role in diverse physiological processes of animals and plants.
Xin Ping Li   +3 more
doaj   +1 more source

Antimicrobial photodynamic therapy in Candida spp. biofilms: In vitro and in vivo protocols

open access: yesPhotochemistry and Photobiology, EarlyView.
This review addresses the critical challenges in translating in vitro antimicrobial photodynamic therapy protocols to in vivo models, with a particular focus on the hurdles of standardization. The vast diversity in photosensitizers and light parameters across different target cells and models requires a rigorous optimization process.
Lívia Mara Alves Figueiredo‐Godoi   +2 more
wiley   +1 more source

Contrasting regulation of live Bacillus cereus No.1 and its volatiles on Shiraia perylenequinone production

open access: yesMicrobial Cell Factories, 2022
Background Fungal perylenequinones (PQs) are a class of photoactivated polyketide mycotoxins produced by plant-associated fungi. Hypocrellins, the effective anticancer photodynamic therapy (PDT) agents are main bioactive PQs isolated from a bambusicolous
Rui Xu   +5 more
doaj   +1 more source

Liposomal Nanoconfinement Enables Type I Photodynamic Conversion for Synergistic Cancer Photothermal‐Immunotherapy

open access: yesAdvanced Science, Volume 13, Issue 23, 23 April 2026.
Liposomal nanoconfinement converts the hemicyanine photosensitizer RhM from Type‐II to Type‐I photodynamic therapy (PDT) while enhancing photothermal therapy (PTT). The RhM‐R837@Lip nanoassembly efficiently generates superoxide (O2•−) and hydroxyl radicals (•OH) to kill tumor cells and achieve tumor ablation.
Minglu Zhang   +14 more
wiley   +1 more source

Solvent Dependence on the Intramolecular Excited-State Proton or Hydrogen Atom Transfer in Hypocrellin [PDF]

open access: yes, 1997
Hypocrellin and its analog, hypericin (Figure 1), are naturally occurring quinones that have been used for centuries as folk medicines in the orient and the occident and that have attracted much interest because of their light-induced toxicity toward the
Petrich, Jacob, English, D., Das, K.
core  

Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan   +5 more
wiley   +1 more source

Perylenequinone Natural Products: Total Synthesis of Hypocrellin A [PDF]

open access: yesThe Journal of Organic Chemistry, 2009
An efficient and stereoselective total synthesis of the perylenequinone natural product hypocrellin A (1) is described. The key features include a potentially biomimetic 1,8-diketone aldol cyclization to set the centrochiral C7,C7'-stereochemistry, bis(trifluoroacetoxy)iodobenzene mediated oxygenation, a palladium-catalyzed decarboxylation, and an ...
Erin M, O'Brien   +4 more
openaire   +2 more sources

Approaches to Enhance Photodynamic Therapy of Lung Cancer: Potential Application of Nanoparticles

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 12, December 2025.
Bioactive ligand‐targeted nanocarriers can accommodate functionalization with numerous targeting ligands for effective delivery of photosensitizers (PSs) within targeted photodynamic therapy. Various targeting moieties including peptides, antibodies, carbohydrates, aptamers, proteins, and PS anticancer molecules can be attached to nanomaterials.
Nokuphila Winifred Nompumelelo Simelane   +1 more
wiley   +1 more source

Home - About - Disclaimer - Privacy