Results 41 to 50 of about 1,024 (191)
Genome Sequencing and Analysis of the Hypocrellin-Producing Fungus Shiraia bambusicola S4201
Shiraia bambusicola has long been used as a traditional Chinese medicine and its major medicinal active metabolite is hypocrellin, which exhibits outstanding antiviral and antitumor properties.
Ning Zhao +6 more
doaj +1 more source
Shiraia bambusicola is a species of the monotypic genus Shiraia in the phylum Ascomycota. In China, it is known for its pharmacological properties that are used to treat rheumatic arthritis, sciatica, pertussis, tracheitis and so forth.
Xi Lin +5 more
core +1 more source
Background Adenosine 5′-triphosphate (ATP) plays both a central role as an intracellular energy source, and a crucial extracellular signaling role in diverse physiological processes of animals and plants.
Xin Ping Li +3 more
doaj +1 more source
Antimicrobial photodynamic therapy in Candida spp. biofilms: In vitro and in vivo protocols
This review addresses the critical challenges in translating in vitro antimicrobial photodynamic therapy protocols to in vivo models, with a particular focus on the hurdles of standardization. The vast diversity in photosensitizers and light parameters across different target cells and models requires a rigorous optimization process.
Lívia Mara Alves Figueiredo‐Godoi +2 more
wiley +1 more source
Background Fungal perylenequinones (PQs) are a class of photoactivated polyketide mycotoxins produced by plant-associated fungi. Hypocrellins, the effective anticancer photodynamic therapy (PDT) agents are main bioactive PQs isolated from a bambusicolous
Rui Xu +5 more
doaj +1 more source
Liposomal nanoconfinement converts the hemicyanine photosensitizer RhM from Type‐II to Type‐I photodynamic therapy (PDT) while enhancing photothermal therapy (PTT). The RhM‐R837@Lip nanoassembly efficiently generates superoxide (O2•−) and hydroxyl radicals (•OH) to kill tumor cells and achieve tumor ablation.
Minglu Zhang +14 more
wiley +1 more source
Solvent Dependence on the Intramolecular Excited-State Proton or Hydrogen Atom Transfer in Hypocrellin [PDF]
Hypocrellin and its analog, hypericin (Figure 1), are naturally occurring quinones that have been used for centuries as folk medicines in the orient and the occident and that have attracted much interest because of their light-induced toxicity toward the
Petrich, Jacob, English, D., Das, K.
core
Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan +5 more
wiley +1 more source
Perylenequinone Natural Products: Total Synthesis of Hypocrellin A [PDF]
An efficient and stereoselective total synthesis of the perylenequinone natural product hypocrellin A (1) is described. The key features include a potentially biomimetic 1,8-diketone aldol cyclization to set the centrochiral C7,C7'-stereochemistry, bis(trifluoroacetoxy)iodobenzene mediated oxygenation, a palladium-catalyzed decarboxylation, and an ...
Erin M, O'Brien +4 more
openaire +2 more sources
Approaches to Enhance Photodynamic Therapy of Lung Cancer: Potential Application of Nanoparticles
Bioactive ligand‐targeted nanocarriers can accommodate functionalization with numerous targeting ligands for effective delivery of photosensitizers (PSs) within targeted photodynamic therapy. Various targeting moieties including peptides, antibodies, carbohydrates, aptamers, proteins, and PS anticancer molecules can be attached to nanomaterials.
Nokuphila Winifred Nompumelelo Simelane +1 more
wiley +1 more source

