Results 51 to 60 of about 1,024 (191)

Green‐Synthesised Nanoconjugates: Advancing Targeted Photodynamic Therapy for Lung Cancer

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
ABSTRACT Lung cancer is a type of cancer that develops around the airways or lungs and continues to be the leading cause of cancer‐related deaths worldwide. This has necessitated the need for innovative therapeutic strategies to overcome the limits of existing therapies such as surgery, chemotherapy and radiotherapy.
Njabulo Henry Sibanda, Anine Crous, Blassan P. George   +2 more
wiley   +1 more source

Perylenequinone Natural Products: Total Synthesis of Hypocrellin A

, 2016
An efficient and stereoselective total synthesis of the perylenequinone natural product hypocrellin A (1) is described. The key features include a potentially biomimetic 1,8-diketone aldol cyclization to set the centrochiral C7,C7′-stereochemistry, bis ...
Erin M. O’Brien (2328625), Barbara J. Morgan (2328628), Carol A. Mulrooney (1957894), Marisa C. Kozlowski (1314135), Patrick J. Carroll (1317183)   +4 more
core   +4 more sources

Sequencing and Functional Annotation of the Whole Genome of Shiraia bambusicola

G3: Genes, Genomes, Genetics, 2020
Shiraia bambusicola is a rare medicinal fungus found in China that causes bamboo plants to decay and die with severe infection. Hypocrellin, its main active ingredient, is widely used in several fields, such as medicine, agriculture, and food industry ...
Xiyi Ren, Yongxiang Liu, Yumei Tan, Yonghui Huang, Zuoyi Liu, Xuanli Jiang   +5 more
doaj   +1 more source

Roles of Oxygen and Photoinduced Acidification in the Light-Dependent Antiviral Activity of Hypocrellin A [PDF]

, 1995
Hypocrellin A displays photoinduced antiviral activity, in particular against the human immunodeficiency virus (HIV), as does its counterpart, hypericin. Although hypocrellin A, like hypericin, executes an excited-state intramolecular proton transfer, it
Carpenter, S., Wannemuehler, Yvonne, Petrich, Jacob, Fehr, Michael   +3 more
core  

Effects of hypocrellin A on expression of vascular endothelial growth factor and endothelin-1 in human umbilical endothelial cells

, 2007
Increased endothelin-1 (ET-1), vascular endothelial growth factor (VEGF) and activation of protein kinase C (PKC) are co-contributors to endothelial hyperpermeability in diabetes.
Seale, PJ, Dang, L, Qu, X
core   +1 more source

Emerging applications of rare‐earth fluoride nanocrystals in medicine and biotechnologies

Responsive Materials, Volume 3, Issue 4, November 2025.
Rare‐earth fluoride nanocrystals (REFNCs) exhibit high responsivity and can be used as multi‐modal agents in medicine and theranostics. This review summarizes recent advances in REFNCs, covering their synthesis, structures, luminescent properties, and applications in multi‐modal imaging and photodynamic therapy, highlighting their theranostic potential
Alain Tressaud, Zhichao Wang, Yuqi Tang, Quan Li   +3 more
wiley   +1 more source

Development and Application of Organic Sonosensitizers in Cancer Therapy

Aggregate, Volume 6, Issue 6, June 2025.
This review provides a comprehensive overview of organic sonosensitizers employed in cancer treatment, describing their underlying mechanisms and structure‐activity relationship in terms of sonodynamic therapy. The significance of nanotechnology and combination therapy with other oncological modalities (photothermal therapy, photodynamic therapy, etc.)
Yuhan Ding, Yuchen Yang, Omer Aras, Feifei An, Mengjiao Zhou, Yichao Chai   +5 more
wiley   +1 more source

Excited-State Processes in Polycyclic Quinones:  The Light-Induced Antiviral Agent, Hypocrellin, and a Comparison with Hypericin [PDF]

, 1996
Hypocrellin is a naturally occurring perylene quinone that possesses light-induced antiviral activity, most notably against the human immunodeficiency virus (HIV), as does the related molecule, hypericin.
Petrich, Jacob, English, D., Fehr, Michael, Das, K., Smirnov, Alexandre   +4 more
core  

Photodynamic potentiality of hypocrellin B and its lanthanide complexes

, 2008
The search for new photosensitizers with strong absorption bands, fast elimination from the body and high singlet oxygen generation quantum yield has been the subject of intensive research over the past two decades.
Vieira, N. D., Toffoli, D. J., Courrol, L. C. [UNIFESP], Gomes, L.   +3 more
core   +1 more source

Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers

Advanced NanoBiomed Research, Volume 5, Issue 6, June 2025.
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska, Andre G. Skirtach, Anna M. Kaczmarek   +2 more
wiley   +1 more source