Results 201 to 210 of about 12,344 (239)
Some of the next articles are maybe not open access.
The Hypocretins and their Role in Narcolepsy
CNS & Neurological Disorders - Drug Targets, 2009A series of discoveries spanning the last decade have uncovered a new neurotransmitter - hypocretin - and its role in energy metabolism, arousal, and addiction. Also, notably, a lack of hypocretin function has been unequivocally associated with the sleep disorder narcolepsy.
Daniel, Kroeger, Luis, de Lecea
openaire +2 more sources
Orexins (Hypocretins) and Adrenal Function
Hormone and Metabolic Research, 2004The recently discovered neuropeptides orexin A and B regulate feeding behavior, neuroendocrine and autonomic functions, and sleep-wakefulness by central mechanisms. The expression of orexins and orexin receptors in various peripheral organs and the presence of orexin A in blood indicate the existence of a peripheral orexin system.
O, Jöhren, N, Brüggemann, P, Dominiak
openaire +2 more sources
Reactive and predictive homeostasis: Roles of orexin/hypocretin neurons.
Neuropharmacology, 2019Homeostasis is the maintenance of a healthy physiological equilibrium in a changing world. Reactive (feedback, counter-regulatory) and predictive (feedforward, anticipatory) homeostatic control strategies are both important for survival.
D. Burdakov
semanticscholar +1 more source
Hypocretins in the Control of Sleep and Wakefulness
Current Neurology and Neuroscience Reports, 2010During the past 10 years since the discovery of hypocretins (Hcrt, also called orexins), the list of their physiologic implications has been growing, from their primary roles in the sleep-wake cycle and feeding to the control of the cardiovascular system, pain, locomotion, stress, and addiction as well as their involvement in psychiatric disorders such
Bonnavion, Patricia, de Lecea, Luis
openaire +3 more sources
Co-localization of hypocretin-1 and hypocretin-2 in the cat hypothalamus and brainstem
Peptides, 2002Hypocretin-1 (hcrt-1) and hypocretin-2 (hcrt-2) are two recently discovered hypothalamic neuropeptides. In the present study, using double immunofluorescent techniques, the co-localization of hcrt-1 and hcrt-2 was examined in neuronal soma and fibers/terminals located, respectively, in the cat hypothalamus and brainstem. In the hypothalamus, all hcrt-1
Jian-Hua, Zhang +3 more
openaire +2 more sources
The Lancet Neurology, 2015
Since their discovery in 1998, the neurotransmitter peptides hypocretin 1, or orexin A, and hypocretin 2, or orexin B, have been implicated in several neuronal systems, including sleep and wake cycles, neuroendocrine and locomotor function, autonomic regulation, feeding behaviour and energy homoeostasis, and also in the pathophysiology of narcolepsy ...
openaire +2 more sources
Since their discovery in 1998, the neurotransmitter peptides hypocretin 1, or orexin A, and hypocretin 2, or orexin B, have been implicated in several neuronal systems, including sleep and wake cycles, neuroendocrine and locomotor function, autonomic regulation, feeding behaviour and energy homoeostasis, and also in the pathophysiology of narcolepsy ...
openaire +2 more sources
2015
The main topic of this book stems from the discovery of two neuropeptides derived from the same precursor, conducted in parallel by two different groups (de Lecea et al. in Proc Natl Acad Sci USA 95:322–327, 1998; Sakurai et al. in Cell 92:573–585, 1998).
openaire +1 more source
The main topic of this book stems from the discovery of two neuropeptides derived from the same precursor, conducted in parallel by two different groups (de Lecea et al. in Proc Natl Acad Sci USA 95:322–327, 1998; Sakurai et al. in Cell 92:573–585, 1998).
openaire +1 more source