Results 61 to 70 of about 13,871 (203)
Journal of Anatomy, EarlyView.Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann +8 more
wiley +1 more source
Annals of the New York Academy of Sciences, Volume 1545, Issue 1, Page 91-104, March 2025.An investigation into the electrophysiological properties of murine ventricular myocardium and stellate ganglia was conducted using the loose patch clamp technique at two distinct age points to assess aging‐mediated alterations in ionic currents. The voltage‐gated inward sodium current, quantified as maximum sodium current (INa(Max)), was reduced with ...
Bonn Lee +5 more
wiley +1 more source
Elevated cortisol concentration in preterm sheep fetuses impacts heart development
Experimental Physiology, EarlyView.Abstract The prepartum rise in cortisol promotes cardiac development and maturation. Here, we investigated the impact of elevated circulating cortisol during mid‐late gestation on cardiac growth and metabolism in fetal sheep. Saline or cortisol (2–3 mg in 4.4 mL/24 h) was infused into the fetal jugular vein from 109 to 116 days gestation (dG, term ...
Reza Amanollahi +9 more
wiley +1 more source
Frontiers in Physiology, 2015 Aquatic and semiaquatic mammals have the capacity of breath hold (apnea) diving. Northern elephant seals (Mirounga angustirostris) have the ability to perform deep and long duration dives; during a routine dive, adults can hold their breath for 25 min ...
Myrna eBarjau Perez-Milicua +3 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma +12 more
wiley +1 more source
Lesch-Nyhan syndrome: A case report
Journal of Indian Society of Pedodontics and Preventive Dentistry, 2008 Lesch-Nyhan syndrome, a rare inborn error of metabolism, is characterized by mental retardation and self-destructive behavior resulting in self-mutilation through biting and scratching.
Kale A, Shah K, Hallikerimath S
doaj
Selection of suitable endogenous reference genes for qPCR in kidney and hypothalamus of rats under testosterone influence. [PDF]
PLoS ONE, 2017 Real-time quantitative PCR (qPCR) is the most reliable and accurate technique for analyses of gene expression. Endogenous reference genes are being used to normalize qPCR data even though their expression may vary under different conditions and in ...
Khadijeh Gholami +4 more
doaj +1 more source
Food Science &Nutrition, Volume 13, Issue 6, June 2025.This study demonstrates that the aqueous extract of Baccaurea ramiflora leaves (BrLAE) possesses significant antioxidant and anti‐inflammatory properties. BrLAE treatment effectively reduced CFA‐induced paw edema, improved hematological and biochemical parameters, and downregulated pro‐inflammatory gene expression in Wistar rats.
Muhammad Nasir Hayat Malik +11 more
wiley +1 more source
Efficient gene targeting by homologous recombination in rat embryonic stem cells.
PLoS ONE, 2010 The rat is the preferred experimental animal in many biological studies. With the recent derivation of authentic rat embryonic stem (ES) cells it is now feasible to apply state-of-the art genetic engineering in this species using homologous recombination.
Stephen Meek +6 more
doaj +1 more source
Lesch-Nyhan Syndrome: Evaluation of a Modified Bite Device to Prevent Bite Injuries
Applied Sciences, 2020 Lesch-Nyhan syndrome (LNS) is a serious form of hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency, a hereditary purine metabolism disorder. The prevalence reported in the literature is 1/380,000 to 235,000 births.
Gaetano Ierardo +4 more
doaj +1 more source