Results 251 to 260 of about 32,906,174 (307)

Hypoxia-Inducible Factor 1-Alpha (HIF-1α) and Cancer: Mechanisms of Tumor Hypoxia and Therapeutic Targeting. [PDF]

Cureus
Basheeruddin M, Qausain S.
europepmc   +1 more source

A Novel tRNA Half mt‐5’‐tiRNA‐Tyr Promotes Colorectal Cancer Proliferation via Inducing HARS2 Succinylation

Advanced Science, EarlyView.
A mitochondria‐derived tRNA half, mt‐5’‐tiRNA‐Tyr, is upregulated in colorectal cancer tissues and plasma and promotes tumor proliferation. It binds HARS2 and promotes CPT1A‐associated HARS2 K91 succinylation, disrupts HARS2–mt‐tRNA‐His association, impairs mitochondrial translation, enhances succinate‐linked metabolic reprogramming, and shows promise ...
Xinliang Gu, Danping Zhu, Xinwei Liu, Shangshang Hu, Xincheng Yang, Junjie Nie, Tao Xu, Yuqin Pan, Mu Xu, Huiling Sun, Shukui Wang   +10 more
wiley   +1 more source

Nanoscale Systems for Local Activation of Hypoxia-Inducible Factor-1 Alpha: A New Approach in Diabetic Wound Management. [PDF]

Int J Nanomedicine
Saber S, Abdelhady R, Elhemely MA, Elmorsy EA, Hamad RS, Abdel-Reheim MA, El-Kott AF, AlShehri MA, Morsy K, Negm S, Kira AY.   +10 more
europepmc   +1 more source

Dynamics simulations of hypoxia inducible factor-1 regulatory network in cancer using formal verification techniques. [PDF]

Front Mol Biosci
Azhar HMF, Saeed MT, Jabeen I.
europepmc   +1 more source

Remifentanil Ameliorates Lipopolysaccharide-Induced Neuroinflammation by Regulating the Phosphatidylinositol 3-Kinase/Serine-Threonine Protein Kinase/Hypoxia-Inducible Factor 1 Alpha Pathway. [PDF]

Pharmacol Res Perspect
Özcan MS, Aşcı H, Karabacak P, Özden ES, İmeci OB, Özmen Ö.   +5 more
europepmc   +1 more source

Hypoxia-Inducible Factor 1-Alpha (HIF-1α): An Essential Regulator in Cellular Metabolic Control. [PDF]

Cureus
Basheeruddin M, Qausain S.
europepmc   +1 more source

Erratum: Investigating the relationship between hypoxia, hypoxia-inducible factor 1, and the optical redox ratio in response to radiation therapy. [PDF]

Biophotonics Discov
Ivers JD, Puvvada N, Quick CM, Rajaram N.   +3 more
europepmc   +1 more source

Correlation Between Intravascular Platelet Aggregation in Tumors and Hypoxia-Inducible Factor 1 Alpha Expression in Epithelial Ovarian Cancer: Implications for Prognosis and Staging. [PDF]

Cancers (Basel)
Ryu JM, Jeong YY, Lee SJ, Choi YS.
europepmc   +1 more source

Hypoxia-inducible factor 1-alpha and lactate dehydrogenase-A axis in metabolic changes and aggression in esophageal squamous-cell carcinoma.

World J Gastrointest Oncol
Chen X, Liu HY, Zhou WB, Zhang LL, Huang J, Bao DW.   +5 more
europepmc   +1 more source

Dexamethasone inhibits the LPS-induced activation of hypoxia-inducible factor 1 alpha (HIF-1α) in macrophages independently of the DUSP1-p38-TTP-HIF-1α regulatory axis

Lockwood C, Daley KK, O’Neil JD, Heighes KJ, Clayton SA, Clark AR.   +5 more
europepmc   +1 more source