Results 211 to 220 of about 132,175 (264)

Hypoxia-Inducible Factors in Rheumatoid Arthritis: Central Pathogenic Roles and Therapeutic Opportunities. [PDF]

J Inflamm Res
Luo TT, He LX, Yin Q, Wang ZF, Zuo J.
europepmc   +1 more source

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source

The role of HIF-1α in innate immune mechanisms and autoimmunity: A double-edged sword. [PDF]

J Biol Chem
Chapple ML, Zaldumbide A, Fagundes RR.
europepmc   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

HIF1α Attenuated the Lung Ischemia-Reperfusion Injury by Activating the miR-485/Notch1 Signalling. [PDF]

J Cell Mol Med
Dai S, Wan X, Xia L, Xu L, Xie C, Wang G, Tang J.   +6 more
europepmc   +1 more source

Trophoblast adaptation to hypoxia: balance and dysfunction. [PDF]

Cell Commun Signal
Li Q, Wei X, Zhang Y, Zeng W, Lin Y.
europepmc   +1 more source

In Vitro Models of Sturge-Weber Syndrome: Strengths, Limitations, and Future Goals. [PDF]

Int J Mol Sci
Manney AB, Nemeth CL, Comi AM.
europepmc   +1 more source

THBS4 Regulates Pulmonary Hypertension via TGF-β/SMAD2 Signaling. [PDF]

Hypertension
Zeng J, Li D, Wang J, Wang R, Huang Z, Bai D, Liu X, Sun D, Fu G, Kang K, Liu X, Yang L, Zhao F, Luo L, Li R, Zhang Y, Gou D.   +16 more
europepmc   +1 more source

HIF-mediated hierarchical hypoxic adaptation, a novel paradigm in heart failure pathogenesis: is there a role for targeted therapies? [PDF]

Front Pharmacol
Yongjie L, Jingjing W, Yimeng S, Aolong W, Rui Y, Jianru W, Bin L, Yongxia W, Xinlu W, Mingjun Z.   +9 more
europepmc   +1 more source

mRNA overexpression of the hypoxia inducible factor 1 alpha subunit gene (HIF1A): An independent predictor of poor overall survival in chronic lymphocytic leukemia

Leukemia Research, 2017
The hypoxia inducible factor 1 (HIF1) is a heterodimeric transcription factor that ultimately regulates cellular responses to changes in oxygen tension. In this study, we examined the potential diagnostic and prognostic potential of the mRNA expression of HIF1 regulatory α-subunit (HIF1A) in chronic lymphocytic leukemia (CLL).
George Dimitriadis, Sotirios Papageorgiou, Diamantina Vasilatou   +2 more
exaly   +5 more sources