Results 211 to 220 of about 65,547 (283)

Uremic toxin p‑cresyl sulfate enhances the calcification of aortic valvular interstitial cells via klotho/sirtuin‑1 signaling. [PDF]

Mol Med Rep
Li SJ, Cheng TY, Kao YH, Chen WY, Chung CC, Trang NN, Chen PH, Chen YJ.   +7 more
europepmc   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Hypoxia-Inducible Factor 1-α in Autoimmune Diseases-Insights from the Paradigm of Hashimoto's Thyroiditis: A Narrative Review. [PDF]

Med Sci (Basel)
Srb N, Milostić-Srb A, Sarić L, Holik D, Šapina M, Fureš R, Talapko J, Škrlec I, Katalinić D, Kovačić B.   +9 more
europepmc   +1 more source

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet, Marie Netchitaïlo, Fanny Fabre, Elise Belaidi, Claire Arnaud, Anne‐Laure Borel, Patrick Levy, Jean‐Louis Pépin, Renaud Tamisier   +8 more
wiley   +1 more source

Association of HIF1α, BNIP3, and BNIP3L with Hypoxia-Related Metabolic Stress in Metabolic Syndrome. [PDF]

Medicina (Kaunas)
Kıran TR, Keskin L, Erdem M, Güçtekin Z, İnceoğlu F.   +4 more
europepmc   +1 more source

The Complex Relation of Branched‐Chain Amino Acids and Inflammation in the Obesity and Diabetes Context

Obesity Reviews, EarlyView.
ABSTRACT In a scenario with increasing cases of obesity and diabetes worldwide, branched‐chain amino acids (BCAA) metabolism has become an important factor in the understanding of these pathologies. More recently, its chronic high plasma levels have been postulated, alongside glucose, inflammatory factors, and other molecules, as an important ...
Bernardo Starling‐Soares, Monique Macedo Coelho, Bruna Guerra Campolina, Camila Kümmel Duarte, Tatiani Uceli Maioli   +4 more
wiley   +1 more source

Expression Analysis of <i>VEGF</i>-Related Hub Genes and Pathways in Breast Cancer: A Comprehensive Bioinformatics Analysis. [PDF]

Iran J Med Sci
Khoshandam M, Rahmanian M, Hedayati Goudarzi MT, Soltaninejad H, Babashah S, Khoshandam M.   +5 more
europepmc   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

The Role and Mechanism of HIF-1α in Regulating A549 Alveolar Epithelial Cell Function Under Hypoxic Conditions. [PDF]

Can Respir J
Zhao W, Wang K, Kou Q, Feng Y, Song L, Wang T.   +5 more
europepmc   +1 more source

The role of constitutive nitric‐oxide synthase in regulation of IKKα after ultraviolet irradiation

Photochemistry and Photobiology, EarlyView.
cNOS enhances IKKα expression following UVB exposure by promoting promoter activation, transcriptional elongation, and Ets‐1 stabilization. These actions sustain IKKα levels, reduce UV‐induced skin carcinogenesis, and highlight cNOS as a key protective factor against solar UV damage.
Yuxi Zhou, Lingying Tong, Bernardo Bastidas, Tao Liu, Madison Wright, Muxiang Zhou, Shiyong Wu   +6 more
wiley   +1 more source