Results 21 to 30 of about 35,357 (236)

Long Non-Coding RNA MEG8 Suppresses Hypoxia-Induced Excessive Proliferation, Migration and Inflammation of Vascular Smooth Muscle Cells by Regulation of the miR-195-5p/RECK Axis

Frontiers in Molecular Biosciences, 2021
It has been recognized that rebalancing the abnormal proliferation and migration of vascular smooth muscle cells (VSMCs) helps relieve vascular injury.
Dexing Xu, Ruozhu Dai, Hao Chi, Wen Ge, Jingfeng Rong   +4 more
doaj   +1 more source

Eukaryotic initiation factor 5A2 mediates hypoxia-induced autophagy and cisplatin resistance

Cell Death and Disease, 2022
Hypoxia-induced cisplatin resistance is a major challenge during non-small cell lung cancer (NSCLC) treatment. Based on previous studies, we further explored the effect of eukaryotic initiation factor 5A2 (eIF5A2) in hypoxia-induced cisplatin resistance.
Guodong Xu, Hang Chen, Shibo Wu, Jiabin Chen, Shufen Zhang, Guofeng Shao, Lebo Sun, Yinyu Mu, Kaitai Liu, Qiaoling Pan, Ni Li, Xiaoxia An, Shuang Lin, Wei Chen   +13 more
doaj   +1 more source

Transforming Growth Factor-beta 1 Involved in the Pathogenesis of Endometriosis through Regulating Expression of Vascular Endothelial Growth Factor under Hypoxia

Chinese Medical Journal, 2017
Background: Endometriosis (EMs) is a common gynecological disorder characterized by endometrial-like tissue outside the uterus. Hypoxia induces the expression of many important downstream genes to regulate the implantation, survival, and maintenance of ...
Yue-Xin Yu, Yin-Ling Xiu, Xi Chen, Ya-Li Li   +3 more
doaj   +1 more source

Effects of Dietary Starch and Dextrin on Growth and Hypoxia Tolerance in Tiger Puffer (Takifugu rubripes)

Progress in Fishery Sciences, 2023
Fish meal and fish oil are important sources of protein and lipid in feeds. The lack of fish meal and fish oil supply has become an important limiting factor for the aquaculture industry.
Shuqing SONG, Yuexing ZHANG, Qiang MA, Houguo XU, Yuliang WEI, Mengqing LIANG   +5 more
doaj   +1 more source

Semaphorin 3A-hypoxia inducible factor 1 subunit alpha co-overexpression enhances the osteogenic differentiation of induced pluripotent stem cells-derived mesenchymal stem cells in vitro

Chinese Medical Journal, 2020
Abstract Background: Mesenchymal stem or stromal cells (MSCs) derived from the induced pluripotent stem cells (iPSCs) have uniform biological activity, which makes the clinical application of MSCs in bone repair possible.
Jing-Yi Li, Ting-Ting Wang, Chong Li, Zhi-Fang Wang, Shan Li, Li Ma, Li-Li Zheng, Li-Shao Guo   +7 more
openaire   +3 more sources

In vivo imaging of brain ischemia using an oxygen-dependent degradative fusion protein probe. [PDF]

PLoS ONE, 2012
Within the ischemic penumbra, blood flow is sufficiently reduced that it results in hypoxia severe enough to arrest physiological function. Nevertheless, it has been shown that cells present within this region can be rescued and resuscitated by restoring
Youshi Fujita, Takahiro Kuchimaru, Tetsuya Kadonosono, Shotaro Tanaka, Yoshiki Hase, Hidekazu Tomimoto, Masahiro Hiraoka, Shinae Kizaka-Kondoh, Masafumi Ihara, Ryosuke Takahashi   +9 more
doaj   +1 more source

DNA Micro-Array Gene Expression Profiling of Angiogenesis in Collagen Gel Culture

Clinical Medicine Insights: Cardiology, 2008
We examined angiogenesis-related gene expression profiles using collagen gel culture and a DNA chip. After isolation of total RNA from cultures before and after capillary tube formation, a mouse whole-genome array study was performed.
Masumi Akita, Keiko Fujita
doaj   +1 more source

In vitro and in vivo Evidence on Intra-tumor Injection of Allogeneic Serum for Immunotherapy in a Mouse Model of Colon Cancer

Iranian Journal of Allergy, Asthma and Immunology, 2022
It is believed that preformed antibodies are responsible for blood transfusion reactions and transplant rejections. In order to remove a tumor, the tissue must be rejected.
Erfan Basirat, Danial Dehghan, Ardeshir Abbasi, Nafiseh Pakravan   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Hypoxia-driven microRNA-27b underlies pathologic cardiac endoreplication in heart disease

Signal Transduction and Targeted Therapy
Heart disease is characterized by stress-induced endoreplication preceding pathological cardiomyocyte overgrowth, yet the upstream regulatory mechanisms linking tissue hypoxia to aberrant cellular growth remain incompletely defined.
Peter Mirtschink, Ting Yuan, Corinne Bischof, Minh Duc Pham, Chaonan Zhu, Akshay Ware, Yijie Mao, Meiqian Wu, Eva-Maria Rogg, Katharina Bottermann, Suam Gonzalez-Gonoggia, Corinne Berthonneche, Bettina Gercken, Eman Hagag, Katrin Strassburger, Samuel Sossalla, Sebastian N. Stehr, Wesley Abplanalp, Nicola Zamboni, Fabio Martelli, Thierry Pedrazzini, Markus Stoffel, Stefanie Dimmeler, Jaya Krishnan   +23 more
doaj   +1 more source