Abstract figure legend Photobiomodulation restores blood–brain barrier (BBB) integrity following hypoxic stress. A multicellular human BBB model comprising brain microvascular endothelial cells, astrocytes and pericytes was established in a transwell system and subjected to acute hypoxia.
Mirriam Domocos +4 more
wiley +1 more source
Exploring the Research Progress of Vascular Dementia and Key Regulatory Molecules: E2F1. [PDF]
Zhang F +5 more
europepmc +1 more source
A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby +3 more
wiley +1 more source
N-Acetylcysteine Reduces Tissue Injury Induced by Oxygen-Glucose Deprivation in an Organotypic Culture of Mouse Cerebral Cortex Slices. [PDF]
Villani C +3 more
europepmc +1 more source
Ketogenic Strategies in Neonatal Hypoxic-Ischemic Encephalopathy-The Road to Opening Up: A Scoping Review. [PDF]
Falsaperla R +7 more
europepmc +1 more source
Neuroprotective Effects of Furanoditerpenes from <i>Spongia (Spongia) Tubulifera</i> through Cyclophilin D Modulation against Ischemia/Reperfusion Injury in BV2 Microglial Cells. [PDF]
Castedo N +8 more
europepmc +1 more source
PARK7-Nrf2 axis mitigates NLRP3-driven inflammation to rescue neurovascular unit from hypoxia/reoxygenation-induced necroptosis. [PDF]
Xie Z +8 more
europepmc +1 more source
Spreading depolarization: A wave that precedes and drives cerebral ischemic cell death-Target for neuroprotection. [PDF]
Pensato U +6 more
europepmc +1 more source
HIF-1α mediated placental ischemic signaling in the development of early-onset preeclampsia. [PDF]
You K +5 more
europepmc +1 more source
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Autophagy in hypoxia-ischemia induced brain injury
The Journal of Maternal-Fetal & Neonatal Medicine, 2012Autophagy is an endogenous tightly regulated process responsible for the degradation of damaged and dysfunctional cellular organelles and protein aggregates. Emerging data indicate a strong and complex interaction among autophagy, apoptosis and necrosis. We studied these interactions in a neonatal model of hypoxia-ischemia (HI).
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