Na(+)/H (+) Exchangers and Intracellular pH in Perinatal Brain Injury. [PDF]
Encephalopathy consequent on perinatal hypoxia-ischemia occurs in 1-3 per 1,000 term births in the UK and frequently leads to serious and tragic consequences that devastate lives and families, with huge financial burdens for society.
Robertson, NJ, Uria-Avellanal, C
core +2 more sources
Systemic pro-inflammatory cytokine status following therapeutic hypothermia in a piglet hypoxia-ischemia model [PDF]
BACKGROUND: Inflammatory cytokines are implicated in the pathogenesis of perinatal hypoxia-ischemia (HI). The influence of hypothermia (HT) on cytokines after HI is unclear. Our aim was to assess in a piglet asphyxia model, under normothermic (NT) and HT
A Bartha +51 more
core +3 more sources
New horizons for newborn brain protection: enhancing endogenous neuroprotection. [PDF]
Intrapartum-related events are the third leading cause of childhood mortality worldwide and result in one million neurodisabled survivors each year. Infants exposed to a perinatal insult typically present with neonatal encephalopathy (NE).
Alonso-Alconada, D +4 more
core +2 more sources
Prenatal Hypoxia Ischemia Increases Male Rat Sexual Behavior
ABSTRACT Introduction Research consistently indicates an association between prenatal hypoxia-ischemia (HI) and mortality and chronic neurological diseases in newborns. HI can cause permanent effects, including mental retardation, motor impairment, learning disabilities, epilepsy, and cerebral palsy ...
Marcia M D, Ferraz +4 more
openaire +2 more sources
Regulation of Cellular Stress Signaling in Bladder Ischemia
Jing-Hua Yang,1 Yedan Li,2 Roya Azad,2 Kazem Azadzoi3 1Department of Surgery, Boston University School of Medicine, Boston, MA, USA; 2Department of Urology, VA Boston Healthcare System, Boston, MA, USA; 3Department of Urology and Department of Pathology,
Yang J, Li Y, Azad R, Azadzoi K
doaj
Early changes in pro-inflammatory cytokine levels in neonates with encephalopathy are associated with remote epilepsy. [PDF]
BackgroundNeonatal seizures are associated with adverse neurologic sequelae including epilepsy in childhood. Here we aim to determine whether levels of cytokines in neonates with brain injury are associated with acute symptomatic seizures or remote ...
Barkovich, A James +6 more
core
Hypoxia–ischemia plays a role in the physiological and pathological processes of various diseases and presents a common challenge for humans under extreme environmental conditions.
Wenxin Li, Guo Shao, Ruifang Qi
doaj +1 more source
THE ROLE OF NEUROGLOBIN IN CEREBRAL ISCHEMIA / HYPOXIA AND OTHER NEUROPATHOLOGY
The aim of the study was to summarize literature data on the localization, functions and role of neuroglobin in ischemia / hypoxia of the brain and neuropathology of different genesis.
Zimatkin S. M. +2 more
doaj +1 more source
Encefalopatía hipóxico-isquémica (EHI) neonatal : necrosis neuronal selectiva, no sólo necrosis y no tan selectiva [PDF]
El sistema nervioso central (SNC) en desarrollo responde a la injuria a través de procesos generales tales como la inflamación, la muerte celular o la necrosis tisular.
Jones, Marta
core
NMNAT3 is protective against the effects of neonatal cerebral hypoxia-ischemia [PDF]
Araki, Toshiyuki +6 more
core +2 more sources

