Results 91 to 100 of about 432,342 (201)

Sickle Mice Are Sensitive to Hypoxia/Ischemia-Induced Stroke but Respond to Tissue-Type Plasminogen Activator Treatment

open access: yes, 2017
Background and Purpose— The effects of lytic stroke therapy in patients with sickle cell anemia are unknown, although a recent study suggested that coexistent sickle cell anemia does not increase the risk of cerebral hemorrhage ...
Chia-Yi Kuan   +6 more
core   +1 more source

mRNA D(2) dopaminergic receptor expression after hypoxia-ischemia in rat immature brain

open access: yes, 2001
Previous studies have shown a reduction of dopaminergic D(2) receptors (D(2)R) in the striatum after hypoxia-ischemia in newborn rats. We show here an early and transient reduction of mRNA D(2)R in nonatrophic brains following hypoxia-ischemia.
Laugier, J   +6 more
core   +1 more source

Hypoxia-Ischemia in the Immature Brain and Mechanisms of Reducing Tissue Damage [PDF]

open access: yes, 2012
Cerebral hypoxia-ischemia in human infants presents a complex clinical problem in that no standardized treatment currently exists. With an understanding of the cellular and metabolic changes brought about during hypoxia-ischemia in the immature brain ...
Lehr, Faculty Advisor, Edgar   +2 more
core  

GFAP mRNA expression in mice after hypoxia-ischemia, assessed by quantitative rt-PCR.

open access: yes, 2013
Cortex from wild-type mice exposed to hypoxia-ischemia on P9, examined by quantitative rt-PCR immediately after (n = 6), 6 h (n = 4), 24 h (n = 3), 3d (n = 4), 7d (n = 4), and 21d (n = 4) after hypoxia-ischemia.
Maryam Faiz (365377)   +9 more
core   +1 more source

LncRNA GABPB1-IT1 is upregulated in ischemia-induced acute kidney injury and downregulates miR-204-5p to promote hypoxia-induced human renal proximal tubular epithelial cell apoptosis

open access: yesKidney & Blood Pressure Research
Introduction: The present study investigated the role of long non-coding RNA (lncRNA) GABPB1-IT1 in ischemia-induced acute kidney injury (AKI). Methods: The expression of GABPB1-IT1 in plasma of patients with ischemia-induced AKI and healthy controls ...
Fang Feng, Ru Zhang, Lihong Long
doaj   +1 more source

Effects of hypoxia and ischemia on autoregulation in postnatal intestine

open access: yes, 1991
Pressure-flow autoregulation was quantified within in vitro intestine from 3- and 35-day-old swine before and after lowering arterial PO2 (hypoxia) or lowering baseline blood flow by means of norepinephrine infusion (ischemia).
P. T. Nowicki   +2 more
core   +1 more source

Hemin as a protective agent in an in vitro model of hypoxia/reoxygenation-induced injury

open access: yesSAGE Open Medicine
Objective: Ischemia-reperfusion injury exacerbates myocardial damage and affects the prognosis of patients with ST-elevation myocardial infarction. This study investigates the potential cytoprotective effects of hemin in an in vitro cardiomyocyte model ...
Zuoyan Wang, Wei Liu
doaj   +1 more source

Hypoxia, ischemia [PDF]

open access: yesJournal of Neurochemistry, 2004
openaire   +1 more source

Preparation of Nanoparticles Loaded with Membrane-Impermeable Peptide AC3-I and Its Protective Effect on Myocardial Ischemia and Reperfusion

open access: yesPharmaceutics
Purpose: It is well known that inhibition of Ca2+/calmodulin-dependent protein kinase II (CaMKII) provides cardiac protection in cases of myocardial ischemia–reperfusion injury.
Yi Liu   +5 more
doaj   +1 more source

Hypoxic and ischemic effects on gene and protein expression levels of paracrine factors by human olfactory mucosa mesenchymal-like stem cells

open access: yesJournal of Neurorestoratology, 2016
Ting Yuan,1* Yi Zhuo,1* Chaying Su,2 Xuan Li,1 Da Duan,1 Lite Ge,1 Pei Wu,1 Hao Wang,1 Yujia Deng,1 Ming Lu1 1Department of Neurosurgery, Second Affiliated Hospital of Hunan Normal University (163 Hospital of the People’s Liberation Army), Changsha,
Yuan T   +9 more
doaj  

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