Results 181 to 190 of about 123,355 (307)

Urethral injury during vaginal delivery: Incidence, management and long‐term outcomes

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study examines the incidence, obstetric risk factors, surgical management, and long‐term outcomes of obstetric‐associated urethral injuries during vaginal deliveries. Methods A retrospective case series was conducted at a single, tertiary university‐affiliated medical center between January 2018 and December 2023.
Yoav Baruch, Ronen Gold, Yariv Stabholz, Michael Lavie, Yariv Yogev, Asnat Groutz   +5 more
wiley   +1 more source

A machine learning model integrating gut microbiota biomarkers for predicting neurological recovery after cerebral hypoxia-ischemia: a single-center study augmented with public data. [PDF]

Front Pharmacol
Kong L, Wang C.
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Human chorionic gonadotropin decreases cerebral cystic encephalomalacia and parvalbumin interneuron degeneration in a pro-inflammatory model of mouse neonatal hypoxia-ischemia. [PDF]

Sci Rep
Miller B, Crider A, Aravamuthan B, Galindo R.   +3 more
europepmc   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Neuroprotective effect of the combination therapy of melatonin and URB447 after neonatal hypoxia-ischemia. [PDF]

BMC Complement Med Ther
Chillida M, Alvarez FJ, de la Parte BH, Catalan A, Alvarez A, Alonso-Alconada D.   +5 more
europepmc   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Combined effects of <b>β</b>-hydroxybutyrate and therapeutic hypothermia in a neonatal hypoxia-ischemia model. [PDF]

J Cereb Blood Flow Metab
Fabres RB, Carvalho AVS, Silva Alós DKD, Machado DN, Spies FF, Cardoso DS, Vido MFC, Martini APR, Mattos MM, Antunes BP, Hoeper E, Venturin GT, Greggio S, Takada SH, Drobyshevsky A, de Fraga LS, Netto CA.   +16 more
europepmc   +1 more source

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

iNew Medicine, EarlyView.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong, Zhenyu Wang, Suyin Yang, Kaige Gao, Xin Yang, Min Tang   +5 more
wiley   +1 more source

Lipidomic Comparison of Detergent-Soluble and Detergent-Resistant Lipid Domains Isolated From Rat Cerebellum and the Effect of Hypoxia-Ischemia Using UPLC-HDMS^E. [PDF]

J Mass Spectrom
Krug SA, He M, Tang N, Bearer C, Kane MA.   +4 more
europepmc   +1 more source