Results 41 to 50 of about 432,342 (201)
Redox Biology, 2020 Hypertonia is pathognomonic of cerebral palsy (CP), often caused by brain injury before birth. To understand the early driving events of hypertonia, we utilized magnetic resonance imaging (MRI) assessment of early critical brain injury in rabbit fetuses (
Jeannette Vasquez-Vivar +6 more
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Roles of nitric oxide in brain hypoxia-ischemia
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1999 A large body of evidence has appeared over the last 6 years suggesting that nitric oxide biosynthesis is a key factor in the pathophysiological response of the brain to hypoxia-ischemia. Whilst studies on the influence of nitric oxide in this phenomenon initially offered conflicting conclusions, the use of better biochemical tools, such as selective ...
Bolaños, Juan P, Almeida, Angeles
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Neonatal Mice Lacking Neuronal Nitric Oxide Synthase Are Less Vulnerable to Hypoxic–Ischemic Injury
Neurobiology of Disease, 1996 We hypothesized that elimination of neuronal nitric oxide synthase (nNOS) by targeted disruption of the nNOS gene would result in amelioration of damage seen after hypoxia–ischemia in the developing brain since nitric oxide (NO) has been implicated in ...
Donna M. Ferriero +3 more
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Tannic Acid Improves Renal Function Recovery after Renal Warm Ischemia–Reperfusion in a Rat Model
Biomolecules, 2020 Background and purpose: Ischemia−reperfusion injury is encountered in numerous processes such as cardiovascular diseases or kidney transplantation; however, the latter involves cold ischemia, different from the warm ischemia found in vascular ...
Louise Alechinsky +10 more
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Neuroprotective effect of neuroglobin in hypoxia/ischemia
Сибирский научный медицинский журнал, 2021 Neuroglobin is a representative of the globin group, an oxygen-binding protein which is predominantly expressed in the nervous system. Despite the large amount of conducted research, its role is still poorly understood. It’s assumed that neuroglobin is able to regulate cell activity in health and disease:in health it provides oxygen homeostasis of ...
E. V. Uzlova, S. M. Zimatkin
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The role of endotoxin, the TNF family of cytokines and intracellular pH in perinatal hypoxic-ischemic brain injury [PDF]
, 2010 To explore the effect of endotoxin as a sensitising agent prior to neonatal hypoxiaischemia differing doses of endotoxin (E. coli lipopolysaccharide, LPS) were given to neonatal mice prior to hypoxia-ischemia, with sensitising effects noted at dosages ...
Kendall, G.
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Cardiac Shock Wave Therapy Attenuates H9c2 Myoblast Apoptosis by Activating the AKT Signal Pathway
Cellular Physiology and Biochemistry, 2014 Background: Previous studies have demonstrated that Cardiac Shock Wave Therapy (CSWT) improves myocardial perfusion and cardiac function in a porcine model of chronic myocardial ischemia and also ameliorates myocardial ischemia in patients with severe ...
Weiwei Yu +7 more
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Aging-associated Alteration in the Cardiac MIF-AMPK Cascade in Response to Ischemic Stress [PDF]
, 2008 An important role for a macrophage migration inhibitory factor (MIF)-AMP-activated protein kinase (AMPK) signaling pathway in ameliorating myocardial damage following ischemia/reperfusion has been described. An aging-associated reduction in AMPK activity
Lin Leng +7 more
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PLoS ONE, 2015 IntroductionHypoxia-ischemia (HI) is a major perinatal problem that results in severe damage to the brain impairing the normal development of the auditory system.
Francisco Jose Alvarez +9 more
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Neural Regeneration Research, 2016 Heat shock protein 70 (HSP70) maintains Ca2+ homeostasis in PC12 cells, which may protect against apoptosis; however, the mechanisms of neuroprotection are unclear.
Yuan Liu +6 more
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