Results 41 to 50 of about 123,355 (307)
Tannic Acid Improves Renal Function Recovery after Renal Warm Ischemia–Reperfusion in a Rat Model
Biomolecules, 2020 Background and purpose: Ischemia−reperfusion injury is encountered in numerous processes such as cardiovascular diseases or kidney transplantation; however, the latter involves cold ischemia, different from the warm ischemia found in vascular ...
Louise Alechinsky +10 more
doaj +1 more source
Redox Biology, 2020 Hypertonia is pathognomonic of cerebral palsy (CP), often caused by brain injury before birth. To understand the early driving events of hypertonia, we utilized magnetic resonance imaging (MRI) assessment of early critical brain injury in rabbit fetuses (
Jeannette Vasquez-Vivar +6 more
doaj +1 more source
Early changes in brain structure correlate with language outcomes in children with neonatal encephalopathy. [PDF]
, 2017 Global patterns of brain injury correlate with motor, cognitive, and language outcomes in survivors of neonatal encephalopathy (NE). However, it is still unclear whether local changes in brain structure predict specific deficits.
Barkovich, A James +9 more
core +2 more sources
Neonatal Mice Lacking Neuronal Nitric Oxide Synthase Are Less Vulnerable to Hypoxic–Ischemic Injury
Neurobiology of Disease, 1996 We hypothesized that elimination of neuronal nitric oxide synthase (nNOS) by targeted disruption of the nNOS gene would result in amelioration of damage seen after hypoxia–ischemia in the developing brain since nitric oxide (NO) has been implicated in ...
Donna M. Ferriero +3 more
doaj +1 more source
Hypoxia-inducible factor: role in cell survival in superoxide dismutase overexpressing mice after neonatal hypoxia-ischemia. [PDF]
, 2019 BackgroundSixty percent of infants with severe neonatal hypoxic-ischemic encephalopathy die, while most survivors have permanent disabilities. Treatment for neonatal hypoxic-ischemic encephalopathy is limited to therapeutic hypothermia, but it does not ...
Ferriero, Donna M +2 more
core
Dying neurons in thalamus of asphyxiated term newborns and rats are autophagic. [PDF]
, 2014 OBJECTIVE: Neonatal hypoxic-ischemic encephalopathy (HIE) still carries a high burden by its mortality and long-term neurological morbidity in survivors. Apart from hypothermia, there is no acknowledged therapy for HIE, reflecting the lack of mechanistic
Adhami +56 more
core +1 more source
Delayed neural network degeneration after neonatal hypoxia‐ischemia [PDF]
Annals of Neurology, 2008 AbstractObjectiveClinical magnetic resonance studies show delayed and ongoing neurodegeneration after neonatal hypoxia‐ischemia (HI), but the mechanisms and timing of this neurodegeneration remain unclear. We used ex vivo diffusion tensor imaging (DTI) and brain neuropathology to determine whether selective injury to white matter tracts occurs after ...
Brian S, Stone +5 more
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Plasticity in the Neonatal Brain following Hypoxic-Ischaemic Injury [PDF]
, 2016 Hypoxic-ischaemic damage to the developing brain is a leading cause of child death, with high mortality and morbidity, including cerebral palsy, epilepsy, and cognitive disabilities.
Hristova, M, Rocha-Ferreira, E
core +7 more sources
Xa inhibitor edoxaban ameliorates hepatic ischemia-reperfusion injury via PAR-2-ERK 1/2 pathway.
PLoS ONEHepatic ischemia-reperfusion injury causes liver damage during surgery. In hepatic ischemia-reperfusion injury, the blood coagulation cascade is activated, causing microcirculatory incompetence and cellular injury.
Koki Maeda +11 more
doaj +1 more source