The effects of hyperglycaemic hypoxia on rectification in rat dorsal root axons [PDF]
, 1994 1. Electrotonic responses to 150 ms current pulses were recorded from isolated rat dorsal roots incubated for at least 3 h with either normal (5 mM) or high (25 mM) D-glucose solutions, and with either normal (25 mM) or low (5 mM) bicarbonate ...
U Schneider +5 more
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Disruption of the Serotonergic System after Neonatal Hypoxia-Ischemia in a Rodent Model
Neurology Research International, 2012 Identifying which specific neuronal phenotypes are vulnerable to neonatal hypoxia-ischemia, where in the brain they are damaged, and the mechanisms that produce neuronal losses are critical to determine the anatomical substrates responsible for ...
Kathryn M. Buller +2 more
doaj +1 more source
A population of immature cerebellar parallel fibre synapses are insensitive to adenosine but are inhibited by hypoxia [PDF]
, 2011 The purine adenosine plays an important role in a number of physiological and pathological processes and is neuroprotective during hypoxia and ischemia.
Mark J. Wall +3 more
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Analysis of GWAS-Derived Schizophrenia Genes for Links to Ischemia-Hypoxia Response of the Brain
Frontiers in Psychiatry, 2020 Obstetric complications (OCs) can induce major adverse conditions for early brain development and predispose to mental disorders, including schizophrenia (SCZ).
Rainald Schmidt-Kastner +7 more
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The Arginase Pathway in Neonatal Brain Hypoxia-Ischemia [PDF]
Developmental Neuroscience, 2018 Brain damage after hypoxia-ischemia (HI) occurs in an age-dependent manner. Neuroprotective strategies assumed to be effective in adults might have deleterious effects in the immature brain. In order to create effective therapies, the complex pathophysiology of HI in the developing brain requires exploring new mechanisms.
Jana Krystofova +4 more
openaire +4 more sources
miR-127 protects proximal tubule cells against ischemia/reperfusion : identification of Kinesin family member 3B as miR-127 target [PDF]
, 2012 Ischemia/reperfusion (I/R) is at the basis of renal transplantation and acute kidney injury. Molecular mechanisms underlying proximal tubule response to I/R will allow the identification of new therapeutic targets for both clinical settings.
Cuppen, E. +52 more
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Central and peripheral determinants of fatigue in acute hypoxia [PDF]
, 2011 This thesis was submitted for the degree of Docter of Philosophy and awarded by Brunel University on 24th March 2011.Fatigue is defined as an exercise-induced decrease in maximal voluntary force produced by a muscle. Fatigue may arise from central and/or
Goodall, Stuart
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The change in the hypoxia resistance at chronic cerebral ischemia
Бюллетень сибирской медицины, 2008 Hypoxia and its related oxidate stress are the direct cause of the neural damage due to chronic cerebral ischemia. Resistance to hypoxia and oxidate stress is the main marker of the human and brain adaptation to chronic ischemia.Hypoxia resistance and ...
Ye. A. Antipenko, A. V. Gustov
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Teràpia gènica amb hHGF en models de dany renal [PDF]
, 2010 La isquèmia renal és una de les principals causes del Fracas Renal Agut i en el context del trasplantament renal predisposa l’òrgan a un dany crònic i a una possible pèrdua de l’empelt. La cèl•lula epitelial tubular representa una de la unitats renals
Franquesa Bartolomé, Marcela +1 more
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KPNA2 promotes angiogenesis by regulating STAT3 phosphorylation
Journal of Translational Medicine, 2022 Purpose Angiogenesis is involved in many pathological and physiological processes and is mainly driven by hypoxia. Karyopherin subunit alpha 2 (KPNA2), a member of the nuclear transport protein family, was recently shown to be induced by hypoxia in ...
Yujie Jia +3 more
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