Results 11 to 20 of about 432,342 (201)
Disruption of the Serotonergic System after Neonatal Hypoxia-Ischemia in a Rodent Model [PDF]
Neurology Research International, 2012 Identifying which specific neuronal phenotypes are vulnerable to neonatal hypoxia-ischemia, where in the brain they are damaged, and the mechanisms that produce neuronal losses are critical to determine the anatomical substrates responsible for ...
Kathryn M. Buller +2 more
doaj +2 more sources
Hypoxia-ischemia and retinal ganglion cell damage
Clinical Ophthalmology, 2008 Retinal hypoxia is the potentially blinding mechanism underlying a number of sight-threatening disorders including central retinal artery occlusion, ischemic central retinal vein thrombosis, complications of diabetic eye disease and some types of glaucoma. Hypoxia is implicated in loss of retinal ganglion cells (RGCs) occurring in such conditions.
Charanjit Kaur +2 more
openaire +5 more sources
Hypoxia–ischemia in the immature brain [PDF]
Journal of Experimental Biology, 2004 SUMMARYThe immature brain has long been considered to be resistant to the damaging effects of hypoxia and hypoxia–ischemia (H/I). However, it is now appreciated that there are specific periods of increased vulnerability, which relate to the developmental stage at the time of the insult.
Susan J, Vannucci, Henrik, Hagberg
openaire +2 more sources
Sex Vulnerabilities to Hypoxia-Ischemia at Birth.
JAMA Netw Open, 2023 This cross-sectional study examines the incidence of hypoxic ischemic encephalopathy in male vs female neonates.
Chalak LF, Pruszynski JE, Spong CY.
europepmc +3 more sources
Histology of Brain Trauma and Hypoxia-Ischemia [PDF]
Academic Forensic Pathology, 2018 Forensic pathologists encounter hypoxic-ischemic (HI) brain damage or traumatic brain injuries (TBI) on an almost daily basis. Evaluation of the findings guides decisions regarding cause and manner of death. When there are gross findings of brain trauma, the cause of death is often obvious.
Petra, Rahaman, Marc R, Del Bigio
openaire +2 more sources
Hypoxia/Ischemia and the Regulation of Neuroglobin and Cytoglobin Expression [PDF]
IUBMB Life, 2004 AbstractIn analogy to hemoglobin (Hb) and myoglobin (Mb), neuroglobin (Ngb) and cytoglobin (Cygb) are supposed to be involved in oxygen (O2) storage and delivery. The Cygb gene harbours both conserved HREs and mRNA stabilization sites, strongly suggestive of an oxygen‐dependent regulation.
Fordel, E. +4 more
openaire +3 more sources
A depletable pool of adenosine in area CA1 of the rat hippocampus [PDF]
, 2001 Adenosine plays a major modulatory and neuroprotective role in the mammalian CNS. During cerebral metabolic stress, such as hypoxia or ischemia, the increase in extracellular adenosine inhibits excitatory synaptic transmission onto vulnerable neurons via
Darren Caldwell +9 more
core +1 more source
Prednisolone as preservation additive prevents from ischemia reperfusion injury in a rat model of orthotopic lung transplantation [PDF]
, 2013 The lung is, more than other solid organs, susceptible for ischemia reperfusion injury after orthotopic transplantation. Corticosteroids are known to potently suppress pro-inflammatory processes when given in the post-operative setting or during ...
Haitham Mutlak +39 more
core +2 more sources
Photonic Technology for In Vivo Monitoring of Hypoxia–Ischemia
Advanced Science, 2022 AbstractSurveillance of physiological parameters of newborns during delivery triggers medical decision‐making, can rescue life and health, and helps avoid unnecessary cesareans. Here, the development of a photonic technology for monitoring perinatal asphyxia is presented and validated in vivo in a preclinical stage.
Ion Olaetxea +5 more
openaire +3 more sources
A population of immature cerebellar parallel fibre synapses are insensitive to adenosine but are inhibited by hypoxia [PDF]
, 2011 The purine adenosine plays an important role in a number of physiological and pathological processes and is neuroprotective during hypoxia and ischemia.
Mark J. Wall +3 more
core +1 more source