Results 31 to 40 of about 20,996 (180)
Design Challenges for GDPR RegTech [PDF]
, 2020 The Accountability Principle of the GDPR requires that an organisation can demonstrate compliance with the regulations. A survey of GDPR compliance software solutions shows significant gaps in their ability to demonstrate compliance. In contrast, RegTech
Brennan, Rob, Crane, Martin, Ryan, Paul
core +2 more sources
A black-box model for neurons [PDF]
, 2019 We explore the identification of neuronal voltage traces by artificial neural networks based on wavelets (Wavenet). More precisely, we apply a modification in the representation of dynamical systems by Wavenet which decreases the number of used functions;
Claumann, Carlos +3 more
core +1 more source
Protograph-Based LDPC Code Design for Shaped Bit-Metric Decoding [PDF]
, 2015 A protograph-based low-density parity-check (LDPC) code design technique for bandwidth-efficient coded modulation is presented. The approach jointly optimizes the LDPC code node degrees and the mapping of the coded bits to the bit-interleaved coded ...
Böcherer, Georg +2 more
core +3 more sources
The Scientific World Journal, 2010 The diabetes-associated human islet amyloid polypeptide (IAPP) is a 37-amino-acid peptide that forms fibrils in vitro and in vivo. Human IAPP fibrils are toxic in a similar manner to Alzheimer's amyloid-β (Aβ) and prion protein (PrP) fibrils.
Nathaniel G. N. Milton, J. Robin Harris
doaj +1 more source
Membrane permeabilization by Islet Amyloid Polypeptide
, 2009 Membrane permeabilization by Islet Amyloid Polypeptide (IAPP) is suggested to be the main mechanism for IAPP-induced cytotoxicity and death of insulin-producing -cells in type 2 diabetes mellitus (T2DM).
Engel, Maarten F.M.
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Pancreatic cancer-associated diabetes mellitus: an open field for proteomic applications. [PDF]
, 2005 Background: Diabetes mellitus is associated with pancreatic cancer in more than 80% of the cases. Clinical, epidemiological, and experimental data indicate that pancreatic cancer causes diabetes mellitus by releasing soluble mediators which interfere ...
BALDO G +11 more
core +1 more source
, 2005 We investigate the stimulus-dependent tuning properties of a noisy ionic conductance model for intrinsic subthreshold oscillations in membrane potential and associated spike generation.
A. Alonso +23 more
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Episodic synchronization in dynamically driven neurons [PDF]
, 2006 We examine the response of type II excitable neurons to trains of synaptic pulses, as a function of the pulse frequency and amplitude. We show that the resonant behavior characteristic of type II excitability, already described for harmonic inputs, is ...
B. Hutcheon +11 more
core +2 more sources
Upsala Journal of Medical Sciences, 2017 Background: Enhanced IAPP production may contribute to islet amyloid formation in type 2 diabetes. The objective of this study was to determine the effects of the saturated fatty acid palmitate on IAPP levels in human β-cells.
Camilla Krizhanovskii +4 more
doaj +1 more source
Islet Amyloid Polypeptide: A Partner in Crime With Aβ in the Pathology of Alzheimer's Disease
Frontiers in Molecular Neuroscience, 2020 Diabetes affects hundreds of millions of patients worldwide. Despite the advances in understanding the disease and therapeutic options, it remains a leading cause of death and of comorbidities globally.
Ana F. Raimundo +8 more
doaj +1 more source